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  1. Varicocele is a condition characterized by dilated, tortuous veins within the pampiniform venous plexus of the scrotal sac. Presence of varicocele is associated with an increased risk of alteration of semen pa...

    Authors: Elie Bou Nasr, Mouath Binhazzaa, Thierry Almont, Pascal Rischmann, Michel Soulie and Eric Huyghe

    Citation: Basic and Clinical Andrology 2017 27:11

    Content type: Research article

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  2. Mammalian reproduction is one of the most complex and fascinating biological phenomenon, which aims to transfer maternal and paternal genetic material to the next generation. At the end of oogenesis and sperma...

    Authors: Itai Gat and Raoul Orvieto

    Citation: Basic and Clinical Andrology 2017 27:9

    Content type: Review article

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  3. Oestrogens and 1α,25(OH)2-vitamin D3 (1,25-D3) are steroids that can provide effects by binding to their receptors localised in the cytoplasm and in the nucleus or the plasma membrane respectively inducing genomi...

    Authors: Ana Paula Zanatta, Vanessa Brouard, Camille Gautier, Renata Goncalves, Hélène Bouraïma-Lelong, Fátima Regina Mena Barreto Silva and Christelle Delalande

    Citation: Basic and Clinical Andrology 2017 27:10

    Content type: Review article

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  4. Male infertility is a devastating problem that affects many couples worldwide. However, the molecular mechanisms and causes of idiopathic male infertility remain unclear. Circulating cell-free nucleic acids ha...

    Authors: Anne Boissière, Anna Gala, Alice Ferrières-Hoa, Tiffany Mullet, Solenne Baillet, Amaël Petiton, Antoine Torre and Samir Hamamah

    Citation: Basic and Clinical Andrology 2017 27:7

    Content type: Review article

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  5. Development of a non-hormonal long-acting reversible contraceptive for men could have a significant impact on reducing unintended pregnancies. Vasalgel™ is a high molecular weight polymer consisting of styrene...

    Authors: Donald Waller, David Bolick, Elaine Lissner, Christopher Premanandan and Gary Gamerman

    Citation: Basic and Clinical Andrology 2017 27:8

    Content type: Research article

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  6. Options for male contraception are limited. The purpose of this study was to use a nonhuman primate model to evaluate Vasalgel™, a high molecular weight polymer being developed as a contraceptive device for men.

    Authors: Angela Colagross-Schouten, Marie-Josee Lemoy, Rebekah I. Keesler, Elaine Lissner and Catherine A. VandeVoort

    Citation: Basic and Clinical Andrology 2017 27:4

    Content type: Research article

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  7. Several studies suggest a decrease in sperm quality in men in the last decades. Therefore, the aim of this work was to assess the influence of male factors (sperm quality and paternal age) on the outcomes of c...

    Authors: Aurélie Chapuis, Anna Gala, Alice Ferrières-Hoa, Tiffany Mullet, Sophie Bringer-Deutsch, Emmanuelle Vintejoux, Antoine Torre and Samir Hamamah

    Citation: Basic and Clinical Andrology 2017 27:2

    Content type: Research article

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  8. Since the 1970s, international research on male contraception has been actively pursued. Hormonal and non-hormonal methods (thermal, chemical) have been tested, leading to clinical trials of interest to thousa...

    Authors: Jean-Claude Soufir

    Citation: Basic and Clinical Andrology 2017 27:3

    Content type: Review article

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  9. Sperm cells are remarkably complex and highly specialized compared to somatic cells. Their function is to deliver to the oocyte the paternal genomic blueprint along with a pool of proteins and RNAs so a new ge...

    Authors: A. Champroux, J. Torres-Carreira, P. Gharagozloo, J. R. Drevet and A. Kocer

    Citation: Basic and Clinical Andrology 2016 26:17

    Content type: Review article

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  10. While the semen analysis has traditionally been relied upon to differentiate fertile and infertile men, its utility has been questioned in the current era of assisted reproductive technologies. The desire for ...

    Authors: Phil Vu Bach and Peter N. Schlegel

    Citation: Basic and Clinical Andrology 2016 26:15

    Content type: Review article

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  11. The human papilloma virus (HPV) infections were addressed with two FDA-approved HPV vaccines: quadrivalent and bivalent vaccine. The objective of this manuscript is to determine the safety of the HPV vaccine.

    Authors: Mohamed Macki and Ali A. Dabaja

    Citation: Basic and Clinical Andrology 2016 26:16

    Content type: Research article

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  12. The evaluation of prepubertal gonadal Leydig cells secretion requires gonadotropin stimulation. Urinary hCG (human chorionic gonadotropin) is currently unavailable in many countries, however, recombinant hCG (...

    Authors: Leticia Ribeiro Oliveira, Thais Kataoka Homma, Renata Reis Woloszynek, Vinícius Nahime Brito and Carlos Alberto Longui

    Citation: Basic and Clinical Andrology 2016 26:13

    Content type: Research article

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  13. According to our literature analysis, there are no data focused on spermatozoa emotional representations in childless men and data on the emotional repercussions of a diagnosis of infertility on men are still ...

    Authors: N. Swierkowski-Blanchard, L. Alter, S. Salama, C. Muratorio, M. Bergere, M. Jaoul, F. Vialard, M. Bailly, J. Selva and F. Boitrelle

    Citation: Basic and Clinical Andrology 2016 26:12

    Content type: Short report

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  14. Congenital malformations of the seminal vesicle are uncommon, and most of them are cystic malformations. If an insult occurs between the 4th and the 13 h gestational week, the embryogenesis of the kidney, uret...

    Authors: Amine Slaoui, Souhail Regragui, Abdelouahad Lasri, Tarik Karmouni, Khalid El Khader, Abdellatif Koutani and Ahmed Ibn Attya

    Citation: Basic and Clinical Andrology 2016 26:10

    Content type: Case report

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  15. Male infertility related to professional reprotoxic exposure has been assessed in several studies. Collaboration between occupational physicians and patients can yield information about the preventive measures...

    Authors: Amélie Christiaens, Irène Sari-Minodier, Sophie Tardieu, Oana Ianos, Sébastien Adnot, Blandine Courbiere and Jeanne Perrin

    Citation: Basic and Clinical Andrology 2016 26:9

    Content type: Research article

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  16. Although the presence of spermatozoa with an abnormally large head is rare, it is associated with low fertility or even total infertility. We reviewed the literature on assisted reproductive technology (ART) s...

    Authors: Bruno Guthauser, Xavier Pollet-Villard, Florence Boitrelle and Francois Vialard

    Citation: Basic and Clinical Andrology 2016 26:8

    Content type: Review article

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  17. Obesity is an increasing public health problem, with two-thirds of the adult population in many Western countries now being either overweight or obese. Male obesity is associated with late onset hypogonadism, ...

    Authors: Kelton Tremellen

    Citation: Basic and Clinical Andrology 2016 26:7

    Content type: Commentary

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  18. NRD convertase, also termed Nardilysin, is a Zn++ metalloendopeptidase that specifically cleaves the N-terminus of arginine and lysine residues into dibasic moieties. Although this enzyme was found located within...

    Authors: D. Segretain, J. Gilleron, J. N. Bacro, M. Di Marco, D. Carette and G. Pointis

    Citation: Basic and Clinical Andrology 2016 26:5

    Content type: Research article

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  19. Vasectomy is currently the only long-acting contraceptive option available for men, despite increasing demand and potentially significant positive impacts on human health of additional male contraceptive optio...

    Authors: Donald Waller, David Bolick, Elaine Lissner, Christopher Premanandan and Gary Gamerman

    Citation: Basic and Clinical Andrology 2016 26:6

    Content type: Research article

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  20. Except for testicular cancer and Hodgkin’s disease, baseline data on semen quality in case of cancers as well as systemic pathologies of the young adult are scarce or based on low sample size.

    Authors: Jacques Auger, Nathalie Sermondade and Florence Eustache

    Citation: Basic and Clinical Andrology 2016 26:3

    Content type: Research article

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  21. For several decades, testosterone and its synthetic derivatives have been used with anabolic and androgenic purposes. These substances were first restricted to professional bodybuilders, but become more and mo...

    Authors: Rabih El Osta, Thierry Almont, Catherine Diligent, Nicolas Hubert, Pascal Eschwège and Jacques Hubert

    Citation: Basic and Clinical Andrology 2016 26:2

    Content type: Review article

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  22. Endothelial dysfunction and microvascular damage play a crurical role in the pathogenesis of erectile dysfunction (ED). Insulin-like growth factor-1 (IGF-1) is one of the growth factors that have a wide range ...

    Authors: Alper Otunctemur, Emin Ozbek, Suleyman Sahin, Levent Ozcan, Murat Dursun, Emre Can Polat, Mustafa Cekmen, Ozgur Doga Ozsoy, Mustafa Erkoc, Eyup Danis and Muammer Bozkurt

    Citation: Basic and Clinical Andrology 2016 26:1

    Content type: Research article

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  23. The annulus is a ring-shaped structure located beneath the plasma membrane that connects the midpiece and the principal piece of mammalian sperm flagellum. It has been suggested that the annulus acts as a morp...

    Authors: Thassadite Dirami, Baptiste Rode, Jean-Philippe Wolf, Gérard Gacon, Emmanuel Dulioust and Aminata Touré

    Citation: Basic and Clinical Andrology 2015 25:10

    Content type: Short report

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  24. Poor semen quality is one of the main causes of infertility. We have generated a set of monoclonal antibodies to human sperm and used them to investigate sperm quality. Some of these antibodies found differenc...

    Authors: Jana Capkova, Hasmik Margaryan, Alena Kubatova, Petr Novak and Jana Peknicova

    Citation: Basic and Clinical Andrology 2015 25:11

    Content type: Research article

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  25. Treatment of differentiated thyroid cancer usually consists of a total thyroidectomy followed by one or several courses of radioiodine (131I). 131I is known to have deleterious effects on radiation sensitive tiss...

    Authors: Camille Esquerré-Lamare, François Isus, Nathalie Moinard and Louis Bujan

    Citation: Basic and Clinical Andrology 2015 25:8

    Content type: Research article

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  26. To investigate the levels of testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prostate-specific antigen (PSA) in prostate cancer patients before and after the switch from degarel...

    Authors: Yoshiyuki Miyazawa, Haruo Kato, Seiji Arai, Yosuke Furuya, Yoshitaka Sekine, Masashi Nomura, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito and Kazuhiro Suzuki

    Citation: Basic and Clinical Andrology 2015 25:7

    Content type: Research article

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  27. To compare sperm parameters and intracytoplasmic sperm injection (ICSI) outcomes for testicular spermatozoa frozen on the day of the biopsy (DO) with those frozen after 24 h of in vitro culture (D1).

    Authors: Laurent Desch, Céline Bruno, Charlène Herbemont, Frédéric Michel, Shaliha Bechoua, Sophie Girod, Paul Sagot and Patricia Fauque

    Citation: Basic and Clinical Andrology 2015 25:6

    Content type: Research article

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  28. In couples presenting with retrograde ejaculation refractory to medical treatment, the first choice of fertility treatment should be Assisted Reproductive Techniques using rapidly purified spermatozoa retrieve...

    Authors: Melanie Philippon, Gilles Karsenty, Benjamin Bernuz, Blandine Courbiere, Thierry Brue, Jacqueline Saïas-Magnan and Jeanne Perrin

    Citation: Basic and Clinical Andrology 2015 25:5

    Content type: Research article

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  29. The Editors of Basic and Clinical Andrology would like to thank all of our reviewers who have contributed to the journal in Volume 24 (2014) and whose valuable support is fundamental to its success.

    Authors: Roger Mieusset

    Citation: Basic and Clinical Andrology 2015 25:4

    Content type: Reviewer acknowledgement

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  30. To assess the cognitive and sexual/hormonal functioning of prostate cancer patients treated with a luteinizing hormone-releasing hormone (LH-RH) agonist, and the relationships thereof with adrenal and residual...

    Authors: Kohei Okamoto, Yositaka Sekine, Masashi Nomura, Hidekazu Koike, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito and Kazuhiro Suzuki

    Citation: Basic and Clinical Andrology 2015 25:3

    Content type: Research article

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  31. To examine human microRNA expression in fertile men and subsequently to compare expression patterns of miRNAs in fertile and infertile men, specifically men with Sertoli Cell Only (SCO) histopathology.

    Authors: Ali A Dabaja, Anna Mielnik, Brian D Robinson, Matthew S Wosnitzer, Peter N Schlegel and Darius A Paduch

    Citation: Basic and Clinical Andrology 2015 25:2

    Content type: Research article

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  32. India is characterized by the presence of a large number of endogamous castes, tribes and religions, having second largest concentration of tribal population in the World with differed genetic ethnicity, lifes...

    Authors: Shivaprasad Holenarasipura Sathyanarayana and Suttur Srikanta Naik Malini

    Citation: Basic and Clinical Andrology 2015 25:1

    Content type: Research article

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  33. Elephantiasis of the external genitalia is characterized by lymphedema and thickening of the subcutaneous tissues. This gives the skin an appearance similar to a pachyderm skin. This pathology is invalidating ...

    Authors: Brahima Kirakoya, Barnabé Zango, Abdoul Karim Paré, Aristide Fasnéwendé Kaboré and Clotaire Yaméogo

    Citation: Basic and Clinical Andrology 2014 24:16

    Content type: Case report

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  34. Intracytoplasmic Sperm Injection (ICSI) is an Assisted Reproduction Technique (ART) which offers the chance to conceive to patients presenting very low sperm counts (cryptozoospermia/severe oligozoospermia). S...

    Authors: Julien Bessonnat, Sophie Brouillet, Sarah Sintzel, Pierre Gillois, Ulrike Bergues, Caroline Boutte-Busquet, Claire Thomas-Cadi and Sylviane Hennebicq

    Citation: Basic and Clinical Andrology 2014 24:15

    Content type: Research article

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  35. Phthalates provide one of the most documented example evidencing how much we must be cautious when using the traditional paradigm based on extrapolation of experimental data from rodent studies for human healt...

    Authors: René Habert, Gabriel Livera and Virginie Rouiller-Fabre

    Citation: Basic and Clinical Andrology 2014 24:14

    Content type: Review article

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  36. Male patients with chronic kidney disease often exhibit the biological and clinical hallmarks of an abnormal hypothalamo–pituitary–gonadal axis. It is known that dialysis does not reverse this impaired endocri...

    Authors: Safouane M Hamdi, Marie Walschaerts, Louis Bujan, Lionel Rostaing and Nassim Kamar

    Citation: Basic and Clinical Andrology 2014 24:11

    Content type: Research article

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  37. The value of varicocele repair and the latter's impact on semen parameters are still subject to debate.

    Authors: Julie Prasivoravong, François Marcelli, Laurent Lemaître, Pascal Pigny, Nassima Ramdane, Marie-Claire Peers, Valérie Mitchell and Jean-Marc Rigot

    Citation: Basic and Clinical Andrology 2014 24:9

    Content type: Research article

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  38. Mucopolysaccharidosis type IH (MPS IH) is a rare autosomal recessive lysosomal storage disorder. Haematopoietic stem cell transplantation (HSCT) has been proposed for the treatment of MPS IH patients and offer...

    Authors: Jean-Pierre Milazzo, Amandine Bironneau, Jean-Pierre Vannier, Agnes Liard-Zmuda, Bertrand Macé and Rives Nathalie

    Citation: Basic and Clinical Andrology 2014 24:8

    Content type: Case report

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  39. Andrology is the study of male reproductive health, its associated medicines, and biology, including functions and diseases that are specific to men, especially with regard to the reproductive organs. This con...

    Authors: Khalid Al Aboud, Daifullah Al Aboud, Sameer Munshi and Ali assiry Halawi

    Citation: Basic and Clinical Andrology 2014 24:7

    Content type: Short report

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  40. Spermatozoa are the smallest and most cyto-differentiated mammalian cells. From a somatic cell-like appearance at the beginning of spermatogenesis, the male germ cell goes through a highly sophisticated proces...

    Authors: Anais Noblanc, Ayhan Kocer and Joël R Drevet

    Citation: Basic and Clinical Andrology 2014 24:6

    Content type: Review article

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Basic and Clinical Andrology is the official journal of the French Society of Andrology (SALF).

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