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  1. The use of flow cytometry (FC) to evaluate sperm DNA fragmentation via deoxynucleotidyl transferase terminal fluorescein dUTP nick-end labeling (TUNEL) has shown inconsistencies compared with conventional fluo...

    Authors: Niloofar Sadeghi, Marziyeh Tavalaee, Abbas Kiani-Esfahani, Aron Moazamian, Parviz Gharagozloo, Robert J. Aitken, Joël R. Drevet and Mohammad Hossein Nasr-Esfahani

    Citation: Basic and Clinical Andrology 2021 31:23

    Content type: Research article

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  2. Extracellular Vesicles (EVs) are membrane-limited particles containing proteins, lipids, metabolites and nucleic acids that are secreted by healthy and cancerous cells. These vesicles are very heterogeneous in...

    Authors: Anne-Sophie Neyroud, Régina Chiechio, Marina Yefimova, Maria Josè Lo Faro, Nathalie Dejucq-Rainsford, Sylvie Jaillard, Pascale Even-Hernandez, Valérie Marchi and Célia Ravel

    Citation: Basic and Clinical Andrology 2021 31:25

    Content type: Review article

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  3. A direct association between metabolic syndrome (MetS) and sperm production/function has been proposed. In this cross-sectional study, we aimed to determine the impact of MetS on sperm survival. Men from infer...

    Authors: Minh Tam Le, Hiep Tuyet Thi Nguyen, Hong Nhan Thi Dang, Thai Thanh Thi Nguyen, Trung Van Nguyen and Quoc Huy Vu Nguyen

    Citation: Basic and Clinical Andrology 2021 31:22

    Content type: Research article

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  4. Sperm cryopreservation, an effective method for preserving male fertility, is very advantageous for men suffering from cancer. Unfortunately, as both physicians and cancer patients are unaware of the possibili...

    Authors: Xiao Liu, Bo Liu, Shasha Liu, Yang Xian, Wenrui Zhao, Bin Zhou, Xiao Xiao, Li Wang, Xiaofang Zhu, Bizhen Shu, Min Jiang and Fuping Li

    Citation: Basic and Clinical Andrology 2021 31:24

    Content type: Research article

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  5. Bromodomain-containing protein 7 (BRD7), a member of the bromodomain-containing protein family, plays important roles in chromatin modification and transcriptional regulation. A recent model of Brd7-knockout mice...

    Authors: Tianrong He, Mohan Liu, Dachang Tao, Xiangyou Leng, Zhaokun Wang, Shengyu Xie, Yangwei Zhang, Xinyue Zhang, Xiaolan Tan, Yunqiang Liu and Yuan Yang

    Citation: Basic and Clinical Andrology 2021 31:19

    Content type: Research article

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  6. Whereas the initially strategy for the genetic analysis of male infertility was based on a candidate gene approach, the development of next-generation sequencing technologies (such as whole-exome sequencing (W...

    Authors: Farah Ghieh, Anne-Laure Barbotin, Clara Leroy, François Marcelli, Nelly Swierkowsky-Blanchard, Valérie Serazin, Béatrice Mandon-Pepin and François Vialard

    Citation: Basic and Clinical Andrology 2021 31:21

    Content type: Commentary

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  7. Asthenozoospermia is a usual male infertility factor, characterized by decreased semen quality. It has been revealed that antioxidants improve sperm function, enhance endogenous antioxidant activities, and pro...

    Authors: Reza Asadpour, Morteza Taravat, Maryam Rahbar, Mohammadrasoul Khoshniyat and Gholamreza Hamidian

    Citation: Basic and Clinical Andrology 2021 31:20

    Content type: Research article

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  8. During the last decades, the abuse of anabolic androgenic steroids (AASs) has become popular among professional and recreational athletes. The abuse of AASs leads to decreased levels of sex hormones, but the a...

    Authors: Jasmina Sretenovic, Jovana Joksimovic Jovic, Ivan Srejovic, Vladimir Zivkovic, Katarina Mihajlovic, Milica Labudovic-Borovic, Svetlana Trifunovic, Verica Milosevic, Dejan Lazic, Sergey Bolevich, Vladimir Jakovljevic and Zoran Milosavljevic

    Citation: Basic and Clinical Andrology 2021 31:17

    Content type: Research article

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  11. Testicular sperm extraction (TESE) is the method of choice for recovering spermatozoa in patients with azoospermia. However, the lack of reliable biomarkers makes it impossible to predict sperm retrieval outco...

    Authors: Hamza Benderradji, Julie Prasivoravong, François Marcelli, Anne-Laure Barbotin, Sophie Catteau-Jonard, Carole Marchetti, Catherine Guittard, Philippe Puech, Valérie Mitchell, Jean-Marc Rigot, Arnauld Villers, Pascal Pigny and Clara Leroy

    Citation: Basic and Clinical Andrology 2021 31:15

    Content type: Research article

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  12. The testis represents one place where the progenitor of vitamin D is converted into its active form. Loss of one testis was suggested to result in reduced vitamin D serum levels. Vitamin D deficiency would rep...

    Authors: Klaus-Peter Dieckmann, Osama Andura, Uwe Pichlmeier, Klaus Martin Otte, Hendrik Isbarn and Christian Wülfing

    Citation: Basic and Clinical Andrology 2021 31:14

    Content type: Research article

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    The Correction to this article has been published in Basic and Clinical Andrology 2021 31:18

  13. Androgen deficiency affects men in the adulthood, causing several harmful effects at the reproductive and behavioural levels. Since aromatase is an enzyme that catalyses the conversion of androgens to estrogen...

    Authors: Giovanni Monastra, Mónica Vazquez-Levin, Maria Salome Bezerra Espinola, Gabriele Bilotta, Antonio Simone Laganà and Vittorio Unfer

    Citation: Basic and Clinical Andrology 2021 31:13

    Content type: Research article

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  14. Sperm growth and maturation are correlated with the expression levels of Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1), a widely expressed protein in the human testicles. The decrease in LRWD1...

    Authors: Jui-Hsiang Hung, Han-Yi Cheng, Yung-Chieh Tsai, Hsien-An Pan, Hany A. Omar, Chien-Chih Chiu, Yin-Mei Su, Yung-Ming Lin and Yen-Ni Teng

    Citation: Basic and Clinical Andrology 2021 31:12

    Content type: Research article

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  15. Diet, one of the components of lifestyle, has been believed to have associations with erectile dysfunction (ED). However, whether there is an association between plant-based diet and ED is remains to be explor...

    Authors: Yi Lu, Jiaqi Kang, Zhongjia Li, Xiao Wang, Kang Liu, Kechong Zhou, Wei Wang and Chen Shen

    Citation: Basic and Clinical Andrology 2021 31:11

    Content type: Research article

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  16. Over the last years, there has been an increasing concern about a global decline in men’s fertility. Specifically, some evidence indicates that sperm quality has decreased over the last years. However, reports...

    Authors: Lucía Rosa-Villagrán, Natalibeth Barrera, José Montes, Carlos Riso and Rossana Sapiro

    Citation: Basic and Clinical Andrology 2021 31:8

    Content type: Research article

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  17. Spermatogenesis is a complex process regulated by a multitude of genes. The identification and characterization of male-germ-cell-specific genes is crucial to understanding the mechanisms through which the cel...

    Authors: Hela Bellil, Farah Ghieh, Emeline Hermel, Béatrice Mandon-Pepin and François Vialard

    Citation: Basic and Clinical Andrology 2021 31:9

    Content type: Review article

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  18. Occludin protein is the primary assembling protein of TJs and the structural basis for tight junction formation between Sertoli cells in the spermatogenic epithelium. The expression of miR-122-5p and occludin ...

    Authors: Limin Liu, Maoying Zhu, Xiaoli Liu, Lumin Fei, Jianyun Shen and Deyu Chen

    Citation: Basic and Clinical Andrology 2021 31:7

    Content type: Research article

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  19. Ferroptosis is an iron-dependent cell death that is distinct from apoptosis. Based on excessive amounts of iron and reactive oxygen species in varicocele (VCL) rats, we hypothesize that ferroptosis might be in...

    Authors: Erfaneh Shaygannia, Mohammad H. Nasr-Esfahani, Fattah Sotoodehnejadnematalahi and Kazem Parivar

    Citation: Basic and Clinical Andrology 2021 31:10

    Content type: Research article

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  20. Gonadotropin releasing hormone agonist (GnRHa) treatment following surgery to correct cryptorchidism restores mini-puberty via endocrinological and transcriptional effects and prevents adult infertility in mos...

    Authors: Faruk Hadziselimovic, Gilvydas Verkauskas and Michael B. Stadler

    Citation: Basic and Clinical Andrology 2021 31:6

    Content type: Review article

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  21. Penile prothesis (PP) is the gold-standard treatment of drug-refractory erectile dysfunction (ED). While postoperative outcomes have been widely described in the literature, there are few data about patient sa...

    Authors: Valentine Frydman, Ugo Pinar, Maher Abdessater, William Akakpo, Pietro Grande, Marie Audouin, Pierre Mozer, Emmanuel Chartier-Kastler, Thomas Seisen and Morgan Roupret

    Citation: Basic and Clinical Andrology 2021 31:4

    Content type: Research article

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  22. Premature ejaculation (PE) is a multifactorial problem with a complicated aetiology that has detrimental effects on female partners’ sexual function. However, there is a lack of studies on the relationship bet...

    Authors: Hu Li, Pan Gao, Jingjing Gao, Xu Wu, Guodong Liu, Yutian Dai, Hui Jiang and Xiansheng Zhang

    Citation: Basic and Clinical Andrology 2021 31:5

    Content type: Research article

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  23. In a previous report, we investigated whether the size of male genitalia similarly exposed to serum testosterone during aging could change with age and found that penile length almost stopped increasing during...

    Authors: Hiroshi Ikegaya, Motofumi Suzuki, Hiroki Kondou, Taketo Kawai, Yusuke Sato, Tadaichi Kitamura and Haruki Kume

    Citation: Basic and Clinical Andrology 2021 31:3

    Content type: Research article

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  24. Spermatic cord torsion (SCT) is a surgical emergency. Any delay in diagnosis or treatment may compromise the vital and functional prognosis of the testicle. The orchiectomy rate remains very high in the litera...

    Authors: Fasnéwindé Aristide Kabore, Klovis Klifford Kabore, Moussa Kabore, Brahima Kirakoya, Clotaire Yameogo, Bienvenue Désiré Ky and Barnabé Zango

    Citation: Basic and Clinical Andrology 2021 31:2

    Content type: Research article

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  25. Approximately 2–10% of patients with varicocele complain of pain. Varicocelectomy for testicular pain is a surgical choice when conservative therapy fails to relieve the pain. Different variables have been rep...

    Authors: Abdullah Al-Gadheeb, Hossam S. El-Tholoth, Abdulaziz Albalawi, Abdulmajeed Althobity, Mussa AlNumi, Tala Alafraa and Amr Jad

    Citation: Basic and Clinical Andrology 2021 31:1

    Content type: Research article

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  26. Idiopathic central precocious puberty (ICPP) is supposed to be non-existent in a context of testicular destruction that is typically present in Klinefelter syndrome (KS). Herein, we describe a rare case of ICP...

    Authors: Salwan Maqdasy, Bertrand Barres, Gaelle Salaun, Marie Batisse-Lignier, Celine Pebrel-Richard, Kelvin H. M. Kwok, André Labbé, Philippe Touraine, Florence Brugnon and Igor Tauveron

    Citation: Basic and Clinical Andrology 2020 30:19

    Content type: Case report

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  27. Erectile dysfunction (ED) has a negative impact on ones’ relationships with poor quality of life as inevitable result. The effects of ED maybe worse in developing countries setting like Tanzania because men’s ...

    Authors: Kenan B. Nyalile, Emmanuel H. P. Mushi, Epiphania Moshi, Beatrice J. Leyaro, Sia E. Msuya and Orgeness Mbwambo

    Citation: Basic and Clinical Andrology 2020 30:20

    Content type: Research article

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  28. In 1999, despite a longstanding use, the WHO manual for the examination of human semen finally proposed to assay several biochemical components of the seminal plasma for a functional exploration of the male ac...

    Authors: Safouane M. Hamdi, Erick Sanchez, Delphine Garimbay and Stéphanie Albarede

    Citation: Basic and Clinical Andrology 2020 30:18

    Content type: Research article

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  29. Patients with proximal penile prosthetic cylindrical complications (PPPCC) can be treated with a direct crural technique without using the original traditional approach. In this article we present our novel di...

    Authors: Ahmed S. Zugail, Maher Abdessater, Abdulmajeed Althobity, Johnny Boustany, Mabel Nuernberg, Abdalla Alhammadi and Sébastien Beley

    Citation: Basic and Clinical Andrology 2020 30:17

    Content type: Research article

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  30. The prevalence of low semen quality and the incidence of testicular cancer have been steadily increasing over the past decades in different parts of the World. Although these conditions may have a genetic or e...

    Authors: Rita Rahban and Serge Nef

    Citation: Basic and Clinical Andrology 2020 30:16

    Content type: Review article

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  31. Germline mosaicism is considered to be a rare event. However, its occurrence is underestimated due to the limited availability of germ cells. The genomic variations that underlie this phenomenon comprise singl...

    Authors: Celine Chalas, Aline Receveur, Nelly Frydman, Nathalie Massin, Gerard Tachdjian, Veronique Drouineaud, Alexandra Benachi, Catherine Patrat and Francois Michael Petit

    Citation: Basic and Clinical Andrology 2020 30:14

    Content type: Research article

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  32. Varicocele is one of the most common causes of reversible male infertility, and 15% of the varicocele patients with normal semen analysis are diagnosed as infertile. According to the current guidelines, varico...

    Authors: Ponco Birowo, J. Rahendra Wijaya, Widi Atmoko and Nur Rasyid

    Citation: Basic and Clinical Andrology 2020 30:15

    Content type: Review article

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  33. Clomiphene citrate has been proposed as pre-treatment for infertile men with non-obstructive, testicular azoospermia (NOA) before surgery for testicular sperm extraction (TESE), especially when serum testoster...

    Authors: Daniela Fietz, Adrian Pilatz, Thorsten Diemer, Florian Wagenlehner, Martin Bergmann and Hans-Christian Schuppe

    Citation: Basic and Clinical Andrology 2020 30:13

    Content type: Case report

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  34. The Sperm Chromatin Structure Assay (SCSA®), in addition to identifying the DNA Fragmentation Index (DFI) also identifies High DNA satiability (HDS), supposed to reflect the nuclear compaction of spermatozoa. ...

    Authors: Z. Mohammadi, M. Tavalaee, P. Gharagozloo, J. R. Drevet and M. H. Nasr-Esfahani

    Citation: Basic and Clinical Andrology 2020 30:12

    Content type: Research article

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  35. Little is known about the histology of contralateral descended testes in boys with unilaterally absent testis. We investigated whether absence of one testis is associated with abnormal tissue architecture of t...

    Authors: Faruk Hadziselimovic, Gilvydas Verkauskas, Beata Vincel, Gunthild Krey and Zacharias Zachariou

    Citation: Basic and Clinical Andrology 2020 30:11

    Content type: Research article

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  36. Benign prostatic hyperplasia (BPH) is one of the most common reproductive disorders in both male dogs and men. Finasteride, a synthetic inhibitor of the enzyme 5α-reductase, is widely used as medical treatment...

    Authors: Daniel S. R. Angrimani, Luana C. Bicudo, Nuria Llamas Luceño, Bruno R. Rui, Matheus F. Silva, João D. A. Losano, Bart Leemans, Ann Van Soom and Camila I. Vannucchi

    Citation: Basic and Clinical Andrology 2020 30:9

    Content type: Research article

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  37. SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) metamorphosed our medical practice. In early June 2020, more than 6,400,000 COVID-19 (coronavirus-19 disease) cases were diagnosed across the world ...

    Authors: S. Hamdi, M. Bendayan, E. Huyghe, J.-C. Soufir, E. Amar, R. El Osta, I. Plotton, C. Delalande, J. Perrin, C. Leroy, A. Bouker, H. Pons, H. Lejeune, G. Robin and F. Boitrelle

    Citation: Basic and Clinical Andrology 2020 30:10

    Content type: Letter to the Editor

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  38. Cryptorchidism (CPT) is an important cause of male infertility. Rubus apetalus is a medicinal plant with a powerful antioxidant potential. We investigated the effects of aqueous and methanolic extracts of R. apet...

    Authors: Désiré Alumeti Munyali, Aimé Césaire Tetsatsi Momo, Georges Romeo Bonsou Fozin, Patrick Brice Deeh Defo, Yannick Petnga Tchatat, Boris Lieunang and Pierre Watcho

    Citation: Basic and Clinical Andrology 2020 30:8

    Content type: Research article

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  39. Hard-flaccid syndrome is gaining increased interest among male sexual dysfunctions in the last years. It is poorly understood and defined. Most of the information comes from online forums. This paper is a revi...

    Authors: Maher Abdessater, Anthony Kanbar, William Akakpo and Sebastien Beley

    Citation: Basic and Clinical Andrology 2020 30:7

    Content type: Review article

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  40. The Inflatable penile prostheses (IPP) are used as definitive treatment for severe erectile dysfunction. Removal of an IPP can be challenging, especially for the non-andrologists and junior urologists. The cla...

    Authors: Abdalla Alhammadi, Maher Abdessater, Abdulmajeed Althobity, Anthony Kanbar, Walid Sleiman, Bertrand Guillonneau, Ahmed Zugail and Sebastien Beley

    Citation: Basic and Clinical Andrology 2020 30:6

    Content type: Research article

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  41. Poor sleep has been linked to a number of adverse health outcomes. Recent studies suggest that late bedtimes, short or long sleep durations, and poor sleep quality may impair semen quality. No study has previo...

    Authors: Julius Edward Miller Hvidt, Ulla Breth Knudsen, Robert Zachariae, Hans Jakob Ingerslev, Marie Tholstrup Philipsen and Yoon Frederiksen

    Citation: Basic and Clinical Andrology 2020 30:5

    Content type: Research article

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  42. Cisplatin (CP) is an extremely effective anticancer agent widely used to treat various cancer types, however, the potential side effects include testicular dysfunction. This study was to investigate, using a r...

    Authors: Tetsuya Kohsaka, Itaru Minagawa, Masashi Morimoto, Takuya Yoshida, Tomohiro Sasanami, Yoshitaka Yoneda, Naoki Ikegaya and Hiroshi Sasada

    Citation: Basic and Clinical Andrology 2020 30:3

    Content type: Research article

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  43. Following publication of the original article [1], the authors reported that the author given names and family names had been transposed. The author names in this correction article are presented correctly.

    Authors: Fanny Jumeau, Julien Sigala, Francisco-Jose Fernandez-Gomez, Sabiha Eddarkaoui, Sophie Duban-Deweer, Luc Buée, Hélène Béhal, Nicolas Sergeant and Valérie Mitchell

    Citation: Basic and Clinical Andrology 2020 30:4

    Content type: Correction

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    The original article was published in Basic and Clinical Andrology 2018 28:10

  44. Even after decades of research men still lack reliable and reversible contraceptive methods comparable to female methods of contraception. Traditional methods of male contraception present a high failure rate ...

    Authors: Barkha Khilwani, Ayesha Badar, Abdul S. Ansari and Nirmal K. Lohiya

    Citation: Basic and Clinical Andrology 2020 30:2

    Content type: Review article

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  45. The development of a canine-specific method of immunocontraception is one of the non-invasive controlling strategies for humanely decreasing the dog population. This study was aimed to investigate the potentia...

    Authors: Atefeh Esmailnejad, Behrooz Nikahval, Asghar Mogheiseh, Romina Karampour and Sanaz Karami

    Citation: Basic and Clinical Andrology 2020 30:1

    Content type: Research article

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  46. Cryptorchidism is a frequent endocrinopathy in boys that has been associated with an increased risk of developing testicular cancer and infertility. The condition is curable by combined surgery and hormonal tr...

    Authors: Faruk Hadziselimovic, Gilvydas Verkauskas, Beata Vincel and Michael B. Stadler

    Citation: Basic and Clinical Andrology 2019 29:18

    Content type: Research article

    Published on:

  47. Numerous tests have been proposed to evaluate sperm DNA integrity. To assess the sperm chromatin dispersion (SCD) test in an andrology laboratory, twenty-five men attending Clermont-Ferrand (France) University...

    Authors: Cécile Grèze, Aline Guttmann, Hanae Pons-Rejraji, Marie-Paule Vasson, Jacqueline Lornage, Lemlih Ouchchane and Florence Brugnon

    Citation: Basic and Clinical Andrology 2019 29:17

    Content type: Research article

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  48. Imidacloprid, a neonicotinoid insecticide, has been associated to severe reproductive toxicity in mammals. Although some preventive measures have been reported, curative strategies are yet to be explored. The ...

    Authors: Aimé Césaire Momo Tetsatsi, Pepin Alango Nkeng-Effouet, Désiré Munyali Alumeti, Georges Roméo Fozin Bonsou, Albert Kamanyi and Pierre Watcho

    Citation: Basic and Clinical Andrology 2019 29:16

    Content type: Research article

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  49. Sleep related painful erection (SRPE) is a rare parasomnia consisting of nocturnal penile tumescence accompanied by pain that awakens the individual. Normal non-painful erections are experienced when awake. No...

    Authors: Maher Abdessater, Anthony Kanbar, Ahmed S. Zugail, Abdalla Al hammadi, Bertrand Guillonneau and Sebastien Beley

    Citation: Basic and Clinical Andrology 2019 29:15

    Content type: Review article

    Published on:

  50. Melatonin has significant antioxidant and hepatoprotective effects in normal and oxidative stress conditions. The aim of the present study was to assess the effects of melatonin on antioxidant, hepatic, and re...

    Authors: Asghar Mogheiseh, Farzaneh Koohi, Saeed Nazifi, Aidin Shojaee Tabrizi, Pegah Taheri and Sina Salavati

    Citation: Basic and Clinical Andrology 2019 29:14

    Content type: Research article

    Published on:

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Basic and Clinical Andrology is the official journal of the French Society of Andrology (SALF).

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Basic and Clinical Andrology

ISSN: 2051-4190