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  1. Obesity is regarded a global public health crisis. It has been implicated in a variety of health problems, but when it comes to male fertility, how and to what extent obesity affects it are poorly understood.

    Authors: Pourya Raee, Zahra Shams Mofarahe, Hamid Nazarian, Mohammad-Amin Abdollahifar, Mahsa Ghaffari Novin, Shahin Aghamiri and Marefat Ghaffari Novin
    Citation: Basic and Clinical Andrology 2023 33:13
    Content type: Research article Published on:

  2. This study was conducted to investigate the therapeutic potential of the skin-derived precursor Schwann cells for the treatment of erectile dysfunction in a rat model of bilateral cavernous nerve injury.

    Authors: Xiaolei Ma, Wende Yang, Pan Nie, Zhenbin Zhang, Zehong Chen and Hongbo Wei
    Citation: Basic and Clinical Andrology 2023 33:11
    Content type: Research article Published on:

  3. This study aimed to compare the clinical outcomes of non-transecting urethroplasty and lingual mucosal urethroplasty in the treatment of iatrogenic bulbar urethral stricture.

    Authors: Wei Le, Denglong Wu, Chengdang Xu, Weidong Zhou and Chao Li
    Citation: Basic and Clinical Andrology 2023 33:12
    Content type: Research article Published on:

  4. Non-obstructive azoospermia (NOA) is considered to be the most severe form of male infertility. Before the emergence of surgical testicular sperm extraction and assisted reproductive technology, NOA patients c...

    Authors: Junjun Li, Fang Yang, Liang Dong, Degui Chang and Xujun Yu
    Citation: Basic and Clinical Andrology 2023 33:9
    Content type: Review article Published on:

  5. We investigated the association between premature ejaculation (PE) and the quality of residential environment from a new perspective to explore the influencing factors of PE, especially in four PE subtypes. We...

    Authors: Xi Liu, Tianle Zhu, Pan Gao, Jingjing Gao, Rui Gao, Hui Jiang and Xiansheng Zhang
    Citation: Basic and Clinical Andrology 2023 33:7
    Content type: Research article Published on:

  6. Erectile function depends on a complex interaction between demographic, metabolic, vascular, hormonal, and psychological factors that trigger erectile dysfunction (ED). In the present study we carried out a cr...

    Authors: Giuseppe Lisco, Vincenzo Triggiani, Nicola Bartolomeo, Maria Isabella Ramunni, Carla Pelusi, Giovanni De Pergola, Edoardo Guastamacchia, Emilio Jirillo and Vito Angelo Giagulli
    Citation: Basic and Clinical Andrology 2023 33:5
    Content type: Research article Published on:

  7. There are several approaches to the surgical treatment of the penile curvature conditionally divided into three large groups: tunica albuginea plication (TAP), corpus cavernosum rotation (CR), and transplantat...

    Authors: Vladimir Vorobev, Vladimir Beloborodov, Andrey Sherbatykh, Alexey Kalyagin, Olga Baklanova, Sergei Popov and Stepan Sidorov
    Citation: Basic and Clinical Andrology 2023 33:10
    Content type: Research article Published on:

  8. Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied.

    Authors: Xin Qian, Xing Tao, Yangyang Gong, Can Ran, Yougang Feng and Hongjian Liu
    Citation: Basic and Clinical Andrology 2023 33:3
    Content type: Research article Published on:

  9. Nicotinamide nucleotide transhydrogenase (NNT) gene deficiency has recently been shown to be involved in Primary Adrenal Insufficiency (PAI). NNT encodes an inner mitochondrial membrane protein that produces larg...

    Authors: Lucile Ferreux, Yasmine Boumerdassi, Emmanuel Dulioust, Xavier Bertagna, Florence Roucher-Boulez, Mathilde Bourdon, Nicolas Thiounn and Catherine Patrat
    Citation: Basic and Clinical Andrology 2023 33:17
    Content type: Case report Published on:

  10. Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide since its discovery in December 2019. Research published since the COVID-19 outbreak has focused on whether semen quality and reproductive hormo...

    Authors: Wenjun Zhang, Li Wang, Jiwei Sun, Linlin Cui, Haobo Zhang and Jingmei Hu
    Citation: Basic and Clinical Andrology 2023 33:4
    Content type: Research article Published on:

  12. The coronavirus disease 2019 (COVID-19) outbreak has had a widespread and profound impact on people’s mental health. The factors associated with mental symptoms among men diagnosed with infertility, a disease ...

    Authors: Zhe Zhang, Yu-Zhuo Yang, Hai-Tao Zhang, Yu Xi, Cun-Tong Wang, De-Feng Liu, Jia-Ming Mao, Hao-Cheng Lin, Wen-Hao Tang, Lian-Ming Zhao, Xian-Sheng Zhang, Yu-Tian Dai and Hui Jiang
    Citation: Basic and Clinical Andrology 2023 33:8
    Content type: Research article Published on:

  13. Despite the documented effects of the coronavirus disease 2019 (COVID-19) on spermatogenesis, the reversibility of these effects is uncertain. We aimed to assess the changes of sperm quality between the infect...

    Authors: Nasreldin Mohammed, Mostafa Kamel, Rabea Ahmed Gadelkareem, Mohammed Ali Zarzour, Adel Kurkar, Ahmed Mohammed Abdel-Moniem and Hosny Behnsawy
    Citation: Basic and Clinical Andrology 2023 33:2
    Content type: Research article Published on:

  14. Bisphenol A (BPA) is one of the most widely used synthetic chemicals worldwide. BPA as an endocrine disruptor affects the reproductive systems through estrogenic and antiandrogenic proprieties. Resveratrol (RE...

    Authors: Hossein Bordbar, Seyedeh-Saeedeh Yahyavi, Ali Noorafshan, Elham Aliabadi and Maryam Naseh
    Citation: Basic and Clinical Andrology 2023 33:1
    Content type: Research article Published on:

  15. Male fertility has gradually become a worldwide problem with limitations in the treatment. Alpha-lipoic acid, has been applied to improve the quality of sperm in clinical practice. However, there was currently...

    Authors: Liang Dong, Fang Yang, Junjun Li, Yulin Li, Xujun Yu and Xiaojin Zhang
    Citation: Basic and Clinical Andrology 2022 32:23
    Content type: Review article Published on:

  16. Because of limited differentiation to endothelium from mesenchymal stem cells, it has been strongly recommended to use endothelial progenitor cells for the regeneration of the damaged endothelium of corpora ca...

    Authors: Jae Heon Kim, Sang Hong Bak, Hee Jo Yang, Seung Whan Doo, Do Kyung Kim, Won Jae Yang, Seung U. Kim, Hong J. Lee and Yun Seob Song
    Citation: Basic and Clinical Andrology 2022 32:21
    Content type: Research article Published on:

  17. At present, there is a lack of standardized preparation methods of sperm antigen for the detection of antisperm antibody (AsAb). To screen sperm antigen mimotopes from a phage display random peptide library an...

    Authors: Jin-Chun Lu, Yan-Mei Ge, Yuan-Hua Xu, Shan-Shan Tang and Yuan-Jiao Liang
    Citation: Basic and Clinical Andrology 2022 32:22
    Content type: Research article Published on:

  18. Sperm cryopreservation is an effective method of fertility preservation for disease-related and social sperm freezing. In total, 662 subjects (range: 15–65 years-of-age; mean: 33.49 ± 8.79 years-of-age) were i...

    Authors: Wenhao Tang, Chenyao Deng, Jiangman Gao, Senlin Tian, Nan Wei, Bin Li, Jianfei Song, Liang Zhang, Han Wu and Hui Jiang
    Citation: Basic and Clinical Andrology 2022 32:18
    Content type: Research article Published on:

  19. Vasitis is a rare condition that may be challenging for the clinical practitioner. Sometimes it is misdiagnosed as incarcerated inguinal hernia; thus, patients end up receiving unnecessary surgery. Compared wi...

    Authors: Yi Hong Li, Zhon min Huang, Ji kuen Yu, Yi Sheng Lin, Chao Yu Hsu and Min Che Tung
    Citation: Basic and Clinical Andrology 2022 32:19
    Content type: Case report Published on:

  20. At present, L-carnitine (LC) and coenzyme Q10 (CoQ10), as used clinically to treat male infertility caused by asthenozoospermia (ASZ) is still mainly administered orally, but some patients with ASZ still show ...

    Authors: Chengren Gou, Zidong Zhou, Zongping Chen, Kun Wang, Congcong Chen, Bo Chen, Ningrui Pan and Xu He
    Citation: Basic and Clinical Andrology 2022 32:17
    Content type: Research article Published on:

  22. The seminal virome and its implications for fertility remain poorly understood. To date, there are no defined panels for the detection of viruses of clinical interest in seminal samples.

    Authors: Beatriz Helena Dantas Rodrigues de Albuquerque, Maryana Thalyta Ferreira Camara de Oliveira, Janaína Ferreira Aderaldo, Mychelle de Medeiros Garcia Torres and Daniel Carlos Ferreira Lanza
    Citation: Basic and Clinical Andrology 2022 32:16
    Content type: Review article Published on:

  23. Previous studies have reported that some patients with headless spermatozoa have poor semen quality, but there has been no published systematic analysis of semen quality in patients with different proportions ...

    Authors: Li-juan Ying, Lin Yu, Tingting Yang, Ying-bi Wu, Jin-yan Xu, Ye-lin Jia, Yan Zheng and Fuping Li
    Citation: Basic and Clinical Andrology 2022 32:20
    Content type: Research article Published on:

  24. To evaluate the stiffness of the tunica albuginea (TA), we used a new noninvasive diagnostic technique called shear wave elastography (SWE). We determined whether SWE values are correlated with the degree of p...

    Authors: Francesco Trama, Ester Illiano, Fabrizio Iacono, Antonio Ruffo, Giovanni di Lauro, Achille Aveta, Felice Crocetto, Celeste Manfredi and Elisabetta Costantini
    Citation: Basic and Clinical Andrology 2022 32:15
    Content type: Research article Published on:

  25. The possible effects of COVID-19 vaccines on reproductive health and male fertility in particular have been discussed intensely by the scientific community and the public since their introduction during the pa...

    Authors: Ziad H. Abd, Samir A. Muter, Ruya Abdulhadi M. Saeed and Omar Ammar
    Citation: Basic and Clinical Andrology 2022 32:13
    Content type: Research article Published on:

  26. Fournier’s gangrene (FG) is a necrotizing fasciitis caused by aerobic and anaerobic bacterial infection that involves genitalia and perineum. Males, in their 60 s, are more affected with 1.6 new cases/100.000/...

    Authors: Alessio Paladini, Giovanni Cochetti, Angelica Tancredi, Matteo Mearini, Andrea Vitale, Francesca Pastore, Paolo Mangione and Ettore Mearini
    Citation: Basic and Clinical Andrology 2022 32:12
    Content type: Case report Published on:

  27. Exposure of men and women to environmental reprotoxic agents is associated with impaired fertility and pregnancy rates after assisted reproductive treatment (ART). Nevertheless, such exposures are generally no...

    Authors: Nadia Nouiakh, Claire Sunyach, Sarah-Lyne Jos, Irène Sari-Minodier, Catherine Metzler-Guillemain, Blandine Courbiere, Florence Bretelle and Jeanne Perrin
    Citation: Basic and Clinical Andrology 2022 32:11
    Content type: Research article Published on:

  28. Cryptorchidism occurs frequently in children with cystic fibrosis. Among boys with cryptorchidism and abrogated mini-puberty, the development of the epididymis and the vas deferens is frequently impaired. This...

    Authors: Faruk Hadziselimovic, Gilvydas Verkauskas and Michael Stadler
    Citation: Basic and Clinical Andrology 2022 32:10
    Content type: Review article Published on:

  29. Excess weight and metabolic disorders have a negative impact on male reproductive functions. The mechanisms involved are numerous and complex and epigenetic mechanisms may also be involved, notably through the...

    Authors: Sarah Saget, Laurent Kappeler, Valérie Grandjean, Patricia Leneuve, Isabelle Berthaut, Céline Faure, Sébastien Czernichow, Chrystèle Racine, Rachel Lévy and Charlotte Dupont
    Citation: Basic and Clinical Andrology 2022 32:9
    Content type: Research article Published on:

  30. Infertility related to varicocele, infections, metabolic dysfunctions, oxidative stress and environmental toxicants is also associated with inflammatory processes that ultimately lead to the activation of the ...

    Authors: Marziyeh Tavalaee, Mohsen Rahmani, Joël R. Drevet and Mohammad Hossein Nasr-Esfahani
    Citation: Basic and Clinical Andrology 2022 32:8
    Content type: Review article Published on:

  31. Sarcoidosis is a multi-system disease characterized by the formation of non-caseating granulomas in various organs. The lungs remain the most frequently affected organ, whereas lesions in the genitourinary sys...

    Authors: Magdalena Ostrowska, Piotr Świniarski, Adam Ostrowski, Filip Ryszard Kowalski, Jan Adamowicz, Dariusz Grzanka, Tomasz Adam Drewa and Kajetan Juszczak
    Citation: Basic and Clinical Andrology 2022 32:7
    Content type: Case report Published on:

  32. Severe or complete asthenozoospermia is a rare entity that can lead to male infertility. In this study, we explored whether different extents of severe or complete asthenozoospermia could affect intracytoplasm...

    Authors: Tong Chen, Demin Fan, Xianlong Wang, Changlin Mao, Yaru Chu, Haobo Zhang, Wen Liu, Sentai Ding, Qingyong Liu, Mingzhen Yuan and Jiaju Lu
    Citation: Basic and Clinical Andrology 2022 32:6
    Content type: Research article Published on:

  33. Erectile dysfunction (ED) often occurs due to cavernous nerve injury (CNI) after colorectal surgery. Cell-based therapies have great potential for the treatment of CNI-related ED; however, it needs to be optim...

    Authors: Zhenbin Zhang, Pan Nie, Wende Yang, Xiaolei Ma, Zehong Chen and Hongbo Wei
    Citation: Basic and Clinical Andrology 2022 32:5
    Content type: Research article Published on:

  34. Penile schwannoma is a rare tumor. They commonly present as an asymptomatic, painless and slow growing mass. Other presentations include sexual dysfunction, most commonly dyspareunia, followed by erectile dysf...

    Authors: Chan Ming Tow, Jonathan Tang, Chan Ming Chun and Joe Lee King Chien
    Citation: Basic and Clinical Andrology 2022 32:4
    Content type: Case report Published on:

  35. A very small number of studies have indicated that azoospermia or negative testicular sperm extraction (TESE) outcomes are linked to depression or erectile dysfunction. However, the data are often weak, confli...

    Authors: Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN and Florence BOITRELLE
    Citation: Basic and Clinical Andrology 2022 32:3
    Content type: Research article Published on:

  36. Spermatogenesis in mammals is a heat-sensitive developmental pathway incompatible with the typical mammalian body temperature of 37 °C. It is thought that this is the reason why the testicles of most mammalian...

    Authors: Faruk Hadziselimovic
    Citation: Basic and Clinical Andrology 2022 32:2
    Content type: Review article Published on:

  37. The ischiocavernosus muscle (ICM) encompasses a pair of short pinnate muscles attached to the pelvic ring. The ICM begins at the ischial tuberosity and ends at the crus of the penis while covering the surface ...

    Authors: Chengren Gou, Tong Liu, Zongping Chen, Zidong Zhou, Tao Song, Kaiyi Mao, Congcong Chen and Bo Chen
    Citation: Basic and Clinical Andrology 2022 32:1
    Content type: Research article Published on:

  38. Hormones like testosterone play a crucial role in performance enhancement and muscle growth. Therefore, various attempts to increase testosterone release and testosterone concentration have been made, especial...

    Authors: Eduard Isenmann, Moritz Schumann, Hannah L. Notbohm, Ulrich Flenker and Philipp Zimmer
    Citation: Basic and Clinical Andrology 2021 31:32
    Content type: Short report Published on:

  40. Non-obstructive azoospermia (NOA) with history of cryptorchidism and idiopathic NOA are the most common forms of NOA without genetic aetiology. Of all patients with one of these two types of NOA, only a few wi...

    Authors: Jacques Singh Sangwan, Claire Petit, Romane Sainte Rose, Cynthia Frapsauce, Laura Dijols, Jean Marc Rigot and Fabrice Guérif
    Citation: Basic and Clinical Andrology 2021 31:30
    Content type: Research article Published on:

  41. Recent studies suggest that serum vitamin D may be associated with semen parameters. In the present cross-sectional study, we attempted to investigate the association between serum vitamin D levels and semen p...

    Authors: Hossein Hajianfar, Elham Karimi, Negar Mollaghasemi, Sheyda Rezaei and Arman Arab
    Citation: Basic and Clinical Andrology 2021 31:29
    Content type: Research article Published on:

  42. Several recent journal articles report that d-chiro-inositol (DCI), primarily known as insulin second messenger, influences steroidogenesis. In particular, new evidence is arising on DCI ability to regulate aroma...

    Authors: Maurizio Nordio, Philip Kumanov, Alfonsina Chiefari and Giulia Puliani
    Citation: Basic and Clinical Andrology 2021 31:28
    Content type: Research article Published on:

  43. Although chromosome rearrangements are responsible for spermatogenesis failure, their impact depends greatly on the chromosomes involved. At present, karyotyping and Y chromosome microdeletion screening are th...

    Authors: Farah Ghieh, Anne-Laure Barbotin, Julie Prasivoravong, Sophie Ferlicot, Béatrice Mandon-Pepin, Joanne Fortemps, Henri-Jean Garchon, Valérie Serazin, Clara Leroy, François Marcelli and François Vialard
    Citation: Basic and Clinical Andrology 2021 31:27
    Content type: Case report Published on:

  44. Although widely used, slow freezing considerably modifies the functions of human spermatozoa. Cryopreservation induces nuclear sperm alterations and cryo-capacitation, reducing the chances of pregnancy. Hypota...

    Authors: Hanae Pons-Rejraji, Solène Vorilhon, Asmaa Difrane, Sandra Dollet, Céline Bourgne, Marc Berger, Laure Chaput, Bruno Pereira, Cyril Bouche, Joël R. Drevet and Florence Brugnon
    Citation: Basic and Clinical Andrology 2021 31:26
    Content type: Research article Published on:

  45. The use of flow cytometry (FC) to evaluate sperm DNA fragmentation via deoxynucleotidyl transferase terminal fluorescein dUTP nick-end labeling (TUNEL) has shown inconsistencies compared with conventional fluo...

    Authors: Niloofar Sadeghi, Marziyeh Tavalaee, Abbas Kiani-Esfahani, Aron Moazamian, Parviz Gharagozloo, Robert J. Aitken, Joël R. Drevet and Mohammad Hossein Nasr-Esfahani
    Citation: Basic and Clinical Andrology 2021 31:23
    Content type: Research article Published on:

  46. Extracellular Vesicles (EVs) are membrane-limited particles containing proteins, lipids, metabolites and nucleic acids that are secreted by healthy and cancerous cells. These vesicles are very heterogeneous in...

    Authors: Anne-Sophie Neyroud, Régina Chiechio, Marina Yefimova, Maria Josè Lo Faro, Nathalie Dejucq-Rainsford, Sylvie Jaillard, Pascale Even-Hernandez, Valérie Marchi and Célia Ravel
    Citation: Basic and Clinical Andrology 2021 31:25
    Content type: Review article Published on:

  47. A direct association between metabolic syndrome (MetS) and sperm production/function has been proposed. In this cross-sectional study, we aimed to determine the impact of MetS on sperm survival. Men from infer...

    Authors: Minh Tam Le, Hiep Tuyet Thi Nguyen, Hong Nhan Thi Dang, Thai Thanh Thi Nguyen, Trung Van Nguyen and Quoc Huy Vu Nguyen
    Citation: Basic and Clinical Andrology 2021 31:22
    Content type: Research article Published on:

  48. Sperm cryopreservation, an effective method for preserving male fertility, is very advantageous for men suffering from cancer. Unfortunately, as both physicians and cancer patients are unaware of the possibili...

    Authors: Xiao Liu, Bo Liu, Shasha Liu, Yang Xian, Wenrui Zhao, Bin Zhou, Xiao Xiao, Li Wang, Xiaofang Zhu, Bizhen Shu, Min Jiang and Fuping Li
    Citation: Basic and Clinical Andrology 2021 31:24
    Content type: Research article Published on:

  49. Bromodomain-containing protein 7 (BRD7), a member of the bromodomain-containing protein family, plays important roles in chromatin modification and transcriptional regulation. A recent model of Brd7-knockout mice...

    Authors: Tianrong He, Mohan Liu, Dachang Tao, Xiangyou Leng, Zhaokun Wang, Shengyu Xie, Yangwei Zhang, Xinyue Zhang, Xiaolan Tan, Yunqiang Liu and Yuan Yang
    Citation: Basic and Clinical Andrology 2021 31:19
    Content type: Research article Published on:

  50. Whereas the initially strategy for the genetic analysis of male infertility was based on a candidate gene approach, the development of next-generation sequencing technologies (such as whole-exome sequencing (W...

    Authors: Farah Ghieh, Anne-Laure Barbotin, Clara Leroy, François Marcelli, Nelly Swierkowsky-Blanchard, Valérie Serazin, Béatrice Mandon-Pepin and François Vialard
    Citation: Basic and Clinical Andrology 2021 31:21
    Content type: Commentary Published on:
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Basic and Clinical Andrology

ISSN: 2051-4190