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Fig. 4 | Basic and Clinical Andrology

Fig. 4

From: Male obesity is associated with sperm telomere shortening and aberrant mRNA expression of autophagy-related genes

Fig. 4

Comparison of relative STL, and autophagy-related mRNAs expression between study groups. A Obesity is associated with significant telomere shortening (p = 0.0117). B-F Comparison of relative mRNA expression between study groups showing significant upregulation of Beclin1 (p = 0.0002) (B), ULK1 (p < 0.0001) (D), and BCL2 (p = 0.0101) (F) in the group with obesity. AMPKa1 (p = 0.7892) (C) and BAX (p = 0.4463) (E) expression levels did not vary significantly across study groups. All data are presented as Mean ± SEM. The independent sample t-test with Welch’s correction was conducted (*P < 0.05, ** P < 0.01, and *** P < 0.001). Abbreviations: STL Sperm Telomere Length, AMPK AMP-activated Protein Kinase, ULK1 Unc-51-Like Kinase 1, BCL2 B-cell Lymphoma 2, BAX BCL2-Associated X

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Basic and Clinical Andrology

ISSN: 2051-4190