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Fig. 9 | Basic and Clinical Andrology

Fig. 9

From: Implantation of skin-derived precursor Schwann cells improves erectile function in a bilateral cavernous nerve injury rat model

Fig. 9

Skin-derived precursors Schwann cells prevented the fibrosis process in corpus cavernosum by downregulating the transforming growth factor/Smad2/3 pathway. A Immunohistochemical staining for TGF-β1 (brown) in penile cross section tissues specimen. B Immunohistochemical staining for p-Smad2/3 (brown) in penile cross section tissues specimen. C, D Quantitative analysis of the AOD value of the TGF-β1 and p-Smad2/3. All the data were depicted as mean ± standard deviation from 5 animals per group. ***p < 0.001; the student’s unpaired t-test was used for two-group comparisons; multiple-group comparisons were carried out by one-way ANOVA followed by the S–N-K test. TGF-β1: transforming growth factor-β1; AOD: Average optical density

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Basic and Clinical Andrology

ISSN: 2051-4190