Fig. 2From: Epigenetic markers in the embryonal germ cell development and spermatogenesisGlobal DNA methylation changes during human embryonal development. Dashed line means the estimated (but still unknown) time points of the remethylation phase in arrested gonocytes. The full methylation pattern is established either until birth or before puberty, and is sustained to the end of spermatogenesis. Dots represent the most important steps of DNA methylation. PGCs – primordial germ cells, SSCs – spermatogonial stem cellsBack to article page