Is BRD7 associated with spermatogenesis impairment and male infertility in humans? A case-control study in a Han Chinese population

Table 4 Comparison of sperm products among different genotypes of the rare variants

Rs	Genotype	No. subjects	Median of SC (25th–75th percentile) (n × 10⁶/ml)	P-values	Median of TSC (25th–75th percentiles) (n × 10⁶/ejaculate)	P-values
rs116422109	TT	1152	49.14(18.53–79.62)	0.899	159.40(52.12–274.13)	0.902
rs116422109	TC	16	38.63(7.74–81.67)		155.42(20.28–311.51)
rs202057136	AA	1157	49.09(18.36–79.96)	0.829	159.40(51.94–274.89)	0.908
rs202057136	AG	11	47.27(25.32–71.43)		132.04(56.75–227.02)
rs115302634	AA	1159	49.14(18.40–79.68)	0.445	159.57(51.96–275.03)	0.532
rs115302634	AG	9	44.46(21.31–81.98)		129.40(47.00–200.77)
rs188183810	CC	1165	49.19(18.55–79.89)	0.273	166.14(64.62–279.00)	0.745
rs188183810	CT	3	27.28(7.58–56.64)		71.67(5.02–271.81)

P-values were calculated using Mann-Whitney U test. SC Sperm concentration, TSC Total sperm count

ISSN: 2051-4190