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Table 3 Effect of different treatments on the diameter of the seminiferous tubes, seminiferous epithelium thickness and peri-vascular fibrosis

From: Rubus apetalus (Rosaceae) improves spermatozoa characteristics, antioxidant enzymes and fertility potential in unilateral cryptorchid rats

Groups

Diameter of the seminiferous

tubes (μm)

Germ cell thickness (μm)

Peri-vascular fibrosis (μm)

Right testis

Left testis

Right testis

Left testis

Right testis

Left testis

2 weeks

N

653.63 ± 12.30

656.73 ± 12.73

229.87 ± 7.07

234.35 ± 5.24

16.63 ± 1.82

16.12 ± 1.81

SO

652.21 ± 12.30

662.39 ± 10.23

230.86 ± 8.72

238.20 ± 8.78

16.41 ± 1.87

16.52 ± 1.72

DW

436.64 ± 12.89#,c

663.31 ± 10.80

0 #, c, ¤

234.26 ± 6.46

48.30 ± 2.76 #, c, ¤

16.87 ± 2.31

VIT E

461.91 ± 12.30

683.26 ± 11.63

0 #, c, ¤

277.43 ± 10.08**

33.91 ± 1.41***

14.52 ± 1.03

AE 12

441.76 ± 9.76

681.67 ± 8.80

0 #, c, ¤

331.69 ± 8.88***

28.06 ± 2.87***

13.33 ± 1.00

AE 60

481.91 ± 8.05**

696.91 ± 8.85

0 #, c, ¤

331.21 ± 11.59***

27.76 ± 2.03***

12.46 ± 0.91

ME 12

480.46 ± 9.18***

667.91 ± 10.37

0 #, c, ¤

358.79 ± 12.71***

25.01 ± 0.95***

14.60 ± 1.40

ME 60

498.59 ± 9.49***

669.76 ± 12.89

0 #, c, ¤

373.02 ± 12.91***

24.94 ± 1.17***

11.46 ± 1.19

4 weeks

N

659.93 ± 9.32

658.1 ± 7.52

228.83 ± 8.50

236.49 ± 9.39

15.65 ± 2.650

16.58 ± 2.68

SO

655.41 ± 12.09

661.36 ± 11.68

229.41 ± 9.13

240.87 ± 10.48

16.64 ± 1.31

16.30 ± 1.01

DW

387.51 ± 7.37#, c, ¤

658.29 ± 9.76

0#, c, ¤

227.03 ± 7.29

40.10 ± 3.26#, c, ¤

16.02 ± 1.02

VIT E

476.63 ± 11.65***

674.2 ± 12.97*

0#, c, ¤

273.39 ± 6.41

34.98 ± 1.09***

16.40 ± 0.63

AE 12

444.09 ± 9.03***

690.06 ± 6.86

0#, c, ¤

335.89 ± 11.20*

27.58 ± 0.95***

12.03 ± 2.23

AE 60

464.37 ± 12.63***

721.57 ± 11.76

0#, c, ¤

382.97 ± 12.14*

26.74 ± 1.06***

12.01 ± 0.95

ME 12

446.34 ± 12.46***

668.67 ± 12.637

0#, c,, ¤

380.61 ± 9.22

{24.27 ± 2.16***

16.61 ± 0.93

ME 60

481.49 ± 10.19***

707.69 ± 11.54

0#, c, ¤

383.66 ± 10.85*

20.16 ± 1.68***

13.34 ± 1.15

8 weeks

N

662.31 ± 9.46

659.86 ± 7.65

241.26 ± 6.65

244.38 ± 7.87

17.20 ± 1.73

17.17 ± 1.59

SO

630.13 ± 4.30

661.63 ± 7.31

236.36 ± 4.50

237.20 ± 4.66

16.27 ± 1.23

16.21 ± 1.35

DW

363.46 ± 9.73#, c, ¤

663.89 ± 10.90

0#, c, ¤

234.83 ± 7.48

45.29 ± 3.84#, c, ¤

16.33 ± 1.63

VIT E

470.23 ± 10.45***

667.16 ± 8.36

0#, c, ¤

279.73 ± 7.37***

34.53 ± 1.54***

16.82 ± 1.38

AE 60

491.01 ± 5.56***

683.04 ± 6.33

0#, c, ¤

411.59 ± 3.81***

23.90 ± 1.76***

12.89 ± 0.97

ME 60

495.87 ± 8.04***

740.66 ± 9.71

0#, c, ¤

428.69 ± 7.48***

29.60 ± 1.30***

13.94 ± 1.16

  1. All values are expressed as mean ± SEM. Number of rats per group = 5
  2. Abbreviations: N normal, SO sham operated, DW distilled water, VIT E vitamin E, AE aqueous extract, ME methanolic extract
  3. #: p < 0.001 compared to normal; c: p < 0.001 compared to sham operated; *p<0.05; **p<0.01; ***p<0.001 compared to DW; ¤: p < 0.001 compared to left testis (same group); ¤: p < 0.001 compared to left testis (same group)