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Table 3 Clinical and sexual parameters of subjects with PE + DM and normal group based on Androgen receptor (GGC)n repeats

From: Longer trinucleotide repeats of androgen receptor are associated with higher testosterone and low oxytocin levels in diabetic premature ejaculatory dysfunction patients

Subjects with PE + DM n = 250

Control subjects n = 125

 

GGC Long stretches (≥26) n = 42

GGC Medium stretches (22–25) n = 110

GGC short stretches (≤21) n = 98

GGC Long stretches (≥26) n = 31

GGC Medium stretches (22–25) n = 79

GGC short stretches (≤21) n = 40

Clinical Parameter

 Age (years)

45 (35–55)

43.5 (32–58)

45 (30–60)

45 (30–60)

46 (32–60)

45 (30–60)

 BMI (Kg/m2)

32.45 (30.8–34.1)

32.25 (30.5–34.0)

31 (30–32)

31.25 (28.9–33.6)

30.8 (27.9–33.7)

31.9 (28.85–35.01)

 Blood Sampling Time (8–10 Am)

9.50 (9.00–10

9.57 (9.15–10)

8.72 (8.15–9.30)

9.00 (8.00–10)

8.65 (8.00–9.30)

8.80 (8.30–9.30)

 Diabetes duration (years)

9.3 (4.21–14.56)

7.85(2.2–13.5)

8.30 (4.5–12.1)

9.67 (6.37–12.98)

8.4 (4.4–12.5)

7.5 (3.3–11.8)

 HbA1C (%)

7.05 (6.2–7.9)*

7.2 (6.4–8.00)*

7.1 (6.3–7.9)*

4.2 (3.9–4.6)

4.1 (3.7–4.5)

4.1 (3.4–4.9)

Hormonal Assays

 Oxytocin (pg/ml)

79.1 (51.9–106.3)

82.85 (65.9–99.8)

83.8 (68.4–97.8)

79.35 (76.5–82.2)

80 (78.9–81.1)

79.5 (77.9–81.2)

 Prolactin (ng/ml)

5.00 (4.01–5.98)

5.11 (4.34–5.95)

5.01 (4.1–6.00)

7.2 (5.6–8.99)

7.1 (5.8–8.50)

6.95 (4.9–8.96)

 Total Testosterone (ng/ml)

4.9 (3.8–5.9)

4.8 (4.4–5.36)

4.8 (3.8–5.8)

5.1 (3.4–6.9)

4.1 (3.9–4.4)

4.9 (4.1–5.8)

 TSH (mIU/L)

2.7 (2.5–2.9)

2.5 (2.1–2.9)0

3.0 (2.5–3.5)

2.9 (2.1–3.8)

3.1 (2.5–3.8)

2.9 (2.1–3.8)

Premature Ejaculation Assessments

 PEDT

22.5 (20–25.1)*

21.9 (17.8–26)*

21.3 (16.8–25.9)*

7.7 (6.57–9.00)

7.4 (6.8–8.19)

7.6 (6.2–9.00)

 Self-estimated IELT (s)

168 (156–180)*

170 (165–175)*

168 (158–178)*

344 (201–488)

342 (224–460)

343 (250–436)

Depression Assessments

 BDI-II

49 (40–58)*

48 (38–58)*

51 (42–60)*

10 (7–13)

11 (9–13)

11 (9–13)

Sexual Assessments

 EF

29.5 (29–30)

29.5 (29–30)

27 (26–28)

27 (26–28)

26.5 (26–27)

26.5 (26–27)

 OR

3 (1–5)

3 (1–5)

5 (3–7)

5 (3–7)

6 (3–9)

6 (3–9)

 SD

7 (6–8)

8 (7–9)

5 (1–9)

5 (1–9)

6 (4–8)

6 (4–8)

 OS

4.5 (3–6)

4.5 (3–6)

6 (4–8)

6 (4–8)

4.5 (3–6)

4.5 (3–6)

 IS

3 (1–5)*

3 (1–5)*

6 (4–8)

7 (6–8)

6 (3–9)

6 (3–9)

 IIEF-15- Score

47 (40–54)

48 (41–55)

49 (39–60)

50 (40–60)

49 (39–59)

49 (39–59)

  1. PE Premature Ejaculatory dysfunction; DM Diabetes mellitus type II; BMI Body mass index; TSH Thyroid stimulating hormone; PEDT Premature ejaculation diagnostic tool; IELT Intravaginal ejaculatory latency time; BDI-II Beck’s Depression Inventory-II; EF Erectile function; OR Orgasmic function; SD Sexual desire; OS Overall satisfaction; IS Intercourse satisfaction; IIEF-15 International index of Erectile Dysfunction-15
  2. Data is presented as median (Interquartile range). Values in (*) p < 0.05 are comparison with the entire control