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Résultats fonctionnels de la radiofréquence par Prostiva© dans le traitement de l’hypertrophie bénigne de la prostate (HBP) non compliquée résistante aux traitements médicamenteux

Functional results of radiofrequency by Prostiva© in the treatment of uncomplicated benign prostatic hypertrophy (BPH) resistant to drug treatments

Basic and Clinical Andrology volume 22, pages 227–232 (2012)Cite this article

Résumé

Objectif

Évaluer prospectivement les résultats fonctionnels de la thermothérapie prostatique par radiofréquence (Prostiva©) sur la gêne urinaire et la vie sexuelle dans le cadre du traitement d’une hypertrophie bénigne de la prostate (HBP) symptomatique non compliquée résistante aux traitements médicamenteux.

Patients et méthodes

Les patients répondant aux critères d’éligibilité à ce traitement édités selon la HAS ont été traités dans notre unité d’urologie. Ils ont été convoqués de façon systématique à un mois pour un examen clinique et paraclinique (débit urinaire maximum [Qmax], résidu postmictionnel [RPM], International Prostate Symptom Score [IPSS]). Ils ont été contactés en décembre 2009 et soumis à un hétéroquestionnaire téléphonique portant sur des scores de gêne urinaire (IPSS), de qualité de vie (question 8 de l’IPSS), d’évaluation des fonctions sexuelles (IIEF, DAN SEX), et d’évaluation subjective du traitement (échelle de Likert).

Résultats

De décembre 2006 à janvier 2009, 20 patients (âge médian: 63 ans) ont été traités par Prostiva©. Quatre patients ont présenté une rétention aiguë d’urine dans le postopératoire immédiat nécessitant un sondage vésical en urgence. Nous avons réalisé l’évaluation systématique de l’ensemble des patients à un mois et en décembre 2009. Le suivi médian était de 20,6 mois (valeurs maximales [12–37 mois]). On a constaté une amélioration significative de l’IPSS (−6,7 points; IC95= [−10,3; −3,1]), une amélioration des fonctions sexuelles, des scores de qualité de vie, et un sentiment d’amélioration globale des symptômes urinaires (+ 1,08 = amélioré sur l’échelle de Likert). Quatre patients ont été considérés comme des échecs du Prostiva©: trois patients ayant repris un traitement médicamenteux, un patient ayant bénéficié d’une résection de la prostate.

Conclusion

Notre étude monocentrique réalisée chez des patients sélectionnés selon les critères de l’HAS a conforté les résultats de la littérature avec des résultats positifs sur la gêne urinaire, une faible morbidité et une amélioration de la qualité de vie déclarée. Elle a démontré l’innocuité de la thermothérapie sur la sexualité des patients et mieux encore, l’impact positif du traitement sur la qualité des érections et la satisfaction des rapports.

Abstract

Objective

To assess prospectively on objective and subjective parameters functional outcomes of prostatic thermotherapy by radiofrequency (Prostiva©) on urinary discomfort and sexual life in the treatment of uncomplicated symptomatic and resistant to drug treatment benign prostatic hypertrophy (BPH).

Patients and methods

Patients with eligibility criteria for this treatment published by HAS have been treated in our urology unit. They were called at one month for a clinical examination and analysis of objective data (maximum urine flow [Qmax], post-voiding residual, international prostate score symptom [IPSS]). They were contacted in December 2009 and submitted to a questionnaire on urinary symptoms (IPSS), quality of life (question 8 of IPSS), assessment of sexual function (IIEF, DAN SEX) and subjective assessment of treatment (Likert score).

Results

From December 2006 to January 2009, 20 patients (median age: 63 years) were treated with Prostiva©. Four patients had acute retention of urine in the immediate postoperative needing a urinary catheterization in emergency. We made a systematic evaluation of all patients at one month and in December 2009. The median follow-up was 20.6 months (12–37 months). There was a significant improvement of IPSS (−6.7 points; IC95= [−10.3; −3.1]), an improvement of sexuality functions, quality of life data, and a sense of global improvement of urinary symptoms (+ 1.8 = improved on the Likert score). Four patients were considered as failures: three patients resumed drug therapy, one patient received a prostate resection.

Conclusion

Our single centre study performed in selected patients according to the criteria of HAS consolidated the results of published studies. Results were positive on urinary symptoms, with a low morbidity and a positive subjective evaluation on symptoms. It demonstrated the safety of thermotherapy on patients’ sexuality and even better, the positive impact of the treatment on erections and satisfaction relations.

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Authors and Affiliations

  1. Service d’urologie, centre hospitalier Victor Dupouy d’Argenteuil, 69 rue du Lieutenant-Colonel Prudhon, F-95107, Argenteuil, France

    J. Jean-Baptiste

  2. Service d’urologie, hôpital Saint-Louis, 10 avenue Claude Vellefaux, F-75010, Paris, France

    P. Meria & F. Desgrandchamps

Authors
  1. J. Jean-Baptiste
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  2. P. Meria
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  3. F. Desgrandchamps
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Correspondence to J. Jean-Baptiste.

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Jean-Baptiste, J., Meria, P. & Desgrandchamps, F. Résultats fonctionnels de la radiofréquence par Prostiva© dans le traitement de l’hypertrophie bénigne de la prostate (HBP) non compliquée résistante aux traitements médicamenteux. Basic Clin. Androl. 22, 227–232 (2012). https://doi.org/10.1007/s12610-012-0197-9

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Basic and Clinical Andrology

ISSN: 2051-4190