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Varicocèle et infertilité masculine

Male infertility and varicocele

Basic and Clinical Andrology volume 22, pages 29–35 (2012)Cite this article

Résumé

Introduction

La responsabilité de l’homme dans l’infertilité du couple est établie par plusieurs travaux. Le but de ce travail est de rapporter les aspects cliniques, spermiologiques de la varicocèle et d’évaluer les résultats de la varicocélectomie rétropéritonéale à ciel ouvert.

Patients et méthodes

Il s’agit d’une étude rétrospective évaluant les résultats de la varicocélectomie rétropéritonéale à ciel ouvert, dans le service d’urologie-andrologie du centre hospitalier et universitaire Aristide-Le-Dantec de Dakar, Sénégal. Nous nous sommes intéressés aux patients suivis pour infertilité du couple, porteurs de varicocèle et chez la (les) partenaire(s) de qui aucune autre cause d’infertilité n’a été décelée. Pour l’évaluation des résultats, nous avons comparé les moyennes des paramètres spermatiques pré-et postopératoires en utilisant le test Z (test de comparaison de deux moyennes sur deux séries appariées). Une différence était considérée comme significative si p inférieur ou égal à 0,05.

Résultats

Cinq cent quatorze dossiers ont été retenus au cours de l’exploitation sur une période de six ans (janvier 2005–décembre 2010). L’âge moyen de nos patients était de 36,5 ± 7,3 ans. L’infertilité était primaire dans 62,4 %. L’exploitation des spermogrammes préopératoires a permis de noter que l’oligozoospermie sévère (33,7 %) était associée à des degrés divers à une asthénozoospermie et à une thératozoospermie. Ces patients étaient suivis avec un recul moyen de 22 mois (6–48 mois). L’amélioration des paramètres spermatiques était significative, concernant la concentration et la mobilité des spermatozoïdes. Le taux de grossesses naturelles obtenu dans la série était de 20,8 %. Aucun cas de grossesse naturelle n’a été noté dans le groupe des patients présentant une azoospermie, mais une induction de la spermatogenèse a été notée dans 20,5 % des cas. Près de deux grossesses sur trois (64 %) ont été notées durant les 12 premiers mois postopératoires.

Conclusion

Le traitement chirurgical de la varicocèle permet d’améliorer les paramètres spermatiques, ce qui non seulement permet l’obtention de grossesses naturelles mais également de simplifier les techniques d’Assistance Médicale à la Procréation (AMP) prévues grâce aux nouveaux paramètres.

Abstract

Introduction

Male responsibility in couple infertility has been established in several studies. The purpose of this research was to report varicocele clinical and spermatic aspects and assess the outcomes of open retroperitoneal varicocelectomy.

Patients and methods

Our study is a retrospective assessment of the outcomes of open retroperitoneal varicocelectomy at the urology department of Aristide Le Dantec teaching hospital (Senegal). Our focus is on patients with varicocelectomy facing couple infertility (inability for sexually active couples who are not using contraceptive methods to obtain a pregnancy over a year), patients among which no other infertility cause was revealed in their partner or partners in polygamist households. To assess the results, we compared the averages of preoperative and postoperative spermatic parameters by using the Z test (comparison test of two averages on two mated series). A difference was regarded as significant if P ≤ 0.05.

Results

Five hundred and fourteen cases were examined over 6 years (January 2005–December 2010). The average age of the patients was 36.5 ± 7.3 years. The infertility was primary in 62.4%. The analysis of the preoperative spermograms revealed that severe oligozoospermia (33.7%) was the most common abnormalities in the sperm cells concentrations. The abnormalities in the sperm cells concentrations were variously connected with an asthenozoospermia and to a theratozoospermia. The patients were monitored with an average hindsight of 22 months (6–48 months). The improvement of the parameters was more significant on the concentration and the mobility of sperm cells. The natural pregnancy rate obtained in our study was 20.8%. The registered pregnancies were more important in the group IV (48%). No case of natural pregnancy was noted in the group I but an induction of the spermatogenesis was noted in 20.5% of the cases. About two thirds of natural pregnancies (64%) were noted during the first 12 post-operative months.

Conclusion

The surgical treatment of varicocele allows improving the spermatic parameters. Not only do these improvements help obtain natural pregnancies but also simplify the techniques of ART planned with the preoperative spermatic parameters.

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Authors and Affiliations

  1. BP 35354, Dakar-Colobane, Dakar, Sénégal

    B. Fall

  2. Service d’urologie-andrologie, hôpital Aristide-Le-Dantec, Dakar, Sénégal

    B. Diao, Y. Sow, A. Sarr, S. Mohamed, B. Sine, P. A. Fall, A. K. Ndoye, M. Ba & B. A. Diagne

  3. Service de cytogénétique et de biologie de la reproduction, hôpital Aristide-Le-Dantec, Dakar, Sénégal

    M. R. Sy

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  1. B. Diao
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  5. A. Sarr
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  10. M. Ba
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Correspondence to B. Fall.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Diao, B., Sy, M.R., Fall, B. et al. Varicocèle et infertilité masculine. Basic Clin. Androl. 22, 29–35 (2012). https://doi.org/10.1007/s12610-012-0157-9

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Basic and Clinical Andrology

ISSN: 2051-4190