Skip to main content

Profil épidémiologique et clinique de l’infertilité masculine à l’hôpital général de Grand-Yoff, Sénégal: à propos de 492 cas

Epidemiological and clinical profile of male infertility in the Senegal’s Grand-Yoff General Hospital in Senegal: a study of 492 cases

Résumé

Objectif

Décrire le profil général de l’infertilité masculine, au Sénégal, en milieu hospitalier.

Matériels et méthodes

Il s’agit d’une étude rétrospective, descriptive, portant sur 492 dossiers de patients vus en consultation pour infertilité conjugale du couple entre 2000 et 2004. L’ensemble des paramètres étudiés portait sur les éléments cliniques et les explorations paracliniques.

Résultats

L’âge moyen des patients était de 39 ans. La durée d’évolution de l’infertilité était en moyenne de six ans. L’infertilité était de type primaire dans 66,5 % des cas. Sur le plan clinique, la varicocèle était l’anomalie la plus souvent retrouvée, soit dans 64,6 % des cas. Le spermogramme était perturbé dans 84,3 % des cas. Les principales perturbations étaient une oligospermie inférieure à 5 millions de spermatozoïes/ml (35,6 %) et une azoospermie dans 28,6 % des cas.

Conclusion

Le profil général de l’infertilité est polymorphe. L’exploration est limitée par la non-disponibilité de la partenaire et l’absence de coordination entre gynécologues et andrologues. L’amélioration de la prise en charge de l’infertilité doit passer par de nouvelles voies de recherche, notamment génétiques et immunologiques, afin d’identifier les causes habituellement cachées de l’infertilité. Elle doit aussi reposer sur une bonne collaboration entre praticiens de santé de la reproduction et la mise en place d’unités d’assistance médicale à la procréation (AMP).

Abstract

Objectives

To describe the general profile of male infertility in Senegal in a hospital setting.

Materials and Methods

A retrospective and descriptive study was carried out concerning the medical records of 492 patients treated for infertility between 2000 and 2004. The data concerned included clinical, laboratory and radiological investigation results.

Results

Mean age of patients was 39 years. The mean duration of the infertility was 6 years. The infertility was primary in 66.5% of cases. Clinically, varicocele was the most common anomaly with 64.6% of cases. Seminal fluid analysis was abnormal in 84.3% of cases. The main anomalies were oligospermia with a count less than 5 million cells/ml in 35.6% of cases and azoospermia in 28.6% of cases.

Conclusion

The general profile of infertility is diverse. Exploration is limited by the non-availability of the sexual partner and the lack of coordination between gynaecologists and andrologists. New approaches, including genetic and immunologic research, could help improve management, by finding causes of infertility that are usually hidden. Collaboration between health professionals to create medically assisted conception units could also improve its management.

Références

  1. Berkowitz JM (1995) Mummy was a fetus: motherhood and fetal ovarian transplantation. J Med Ethics 21:298–304

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  2. Leridon H (1991) Stérilité et hypofertilité: du silence à l’impatience. Population 20:227–248

    Google Scholar 

  3. Barber HRK, Fields DH, Kaufman SA (1990) Quick Reference to OB-GYN Procedures. Lippincott, Philadelphia, pp. 494–496

    Google Scholar 

  4. WHO (2000) Manual for the standardised investigation and diagnostis of the infertile couple. Cambridge university press, Cambridge, pp. 60–61

    Google Scholar 

  5. Auger J, Kunstmann JM, Czyglik F, Jouannet P (1995) Decline in semen quality among fertile men in Paris during the past 20 years. N Engl J Med 332:281–285

    Article  PubMed  CAS  Google Scholar 

  6. Pasquet-Février M, Colligon I, Spentchian, et al (1995) Dosage des gonadotrophines FSH et LH par la méthode Access évaluation. Spectra biologie 2:3–10

    Google Scholar 

  7. Pedigo NG, Vernon MW, Curry TE Jr. (1989) Characterization of a computerized semen analysis system. Fertil Steril 52:659–666

    PubMed  CAS  Google Scholar 

  8. Kaufmann RB, Spitz AM, Strauss LT, et al (1998) The decline in US teen pregnancy rate, 1990–1995. Pediatrics 102:1141–1147

    Article  PubMed  CAS  Google Scholar 

  9. Pearce D, Cantisani G, Laihonen A (1999) Changes in fertility and family sizes in Europe. Popul Trends 95:33–40

    PubMed  Google Scholar 

  10. Ikechebelu JI, Adinma JI, Orie EF, Ikegwuonu SO (2003) High prevalence of male infertility in southeastern Nigeria. J Obstet Gynaecol 23:657–659

    Article  PubMed  CAS  Google Scholar 

  11. Ahmed J (1986) Polygyny and fertility differentials among the Yoruba of western Nigeria. J Biosoc Sci 18:63–73

    PubMed  CAS  Google Scholar 

  12. Thonneau P, Ducot B, Bujan L, et al (1997) Effect of male occupational heat exposure on time to pregnancy. Int J Androl 20:274–278

    Article  PubMed  CAS  Google Scholar 

  13. Schwartz D, Mayaux MJ, Spira A, et al (1983) Semen characteristics as a function of age in 833 fertile men. Fertil Steril 39:530–535

    PubMed  CAS  Google Scholar 

  14. Van Waeleghem K, De Clercq N, Vermeulen L, et al (1996) Deterioration of sperm quality in young healthy Belgian men. Hum Reprod 11:325–329

    Article  PubMed  Google Scholar 

  15. Aafjes JH, Van der Vijver JC (1985) Fertility of men with and without varicocele. Fertil Steril 43:901–904

    PubMed  CAS  Google Scholar 

  16. Dubin L, Amelar RD (1977) Varicocelectomy: 986 cases in a twelve-year study. Urology 10:446–449

    Article  PubMed  CAS  Google Scholar 

  17. Sigman M, Jarrow JP (1997) Ipsilateral testicular hypotrophy is associated with decreased sperm counts in infertile men with varicoceles. J Urol 158:605–607

    Article  PubMed  CAS  Google Scholar 

  18. Hendry WF, Polani PE, Pugh RC, et al (1975) Correlation of chromosome, histological endocrine and clinical studies. Br J Urol 47:899–908

    Article  PubMed  CAS  Google Scholar 

  19. Reteif AE, Van Zyl JA, Menkveld R, et al (1984) Chromosome studies in 496 infertile males with a sperm count below 10 million/ml. Hum Genet 66:162–164

    Article  Google Scholar 

  20. Vincent MC, Daudin M, De Mas MP, et al (2002) Cytogenetic investigations of infertile men with low sperm counts: a 25-year experience. J Androl 23:18–22

    PubMed  Google Scholar 

  21. Jarrow JP, Espeland MA, Lipshultz LI (1989) Evaluation of the azoospermic patient. J Urol 142:62–65

    Google Scholar 

  22. Belker AM, Steinbock GS (1990) Transrectal prostate ultrasonography as a diagnostic and therapeutic aid for ejaculatory duct obstruction. J Urol 144:356–358

    PubMed  CAS  Google Scholar 

  23. Gdoura R, Kchaou W, Ammar-Keskes L, et al (2008) Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, and Mycoplasma genitalium in semen and first void urine specimens of asymptomatic male partners of infertile couples. J Androl 29:198–206

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. Niang.

Rights and permissions

Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Reprints and permissions

About this article

Cite this article

Niang, L., Ndoye, M., Labou, I. et al. Profil épidémiologique et clinique de l’infertilité masculine à l’hôpital général de Grand-Yoff, Sénégal: à propos de 492 cas. Basic Clin. Androl. 19, 103–107 (2009). https://doi.org/10.1007/s12610-009-0019-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12610-009-0019-x

Mots clés

Keywords