- Article Original
- Morphologie du Spermatozoïde et Fertilité
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Une forme de tératozoospermie monomorphe: Le syndrome des spermatozoïdes macrocéphales et ses variants
Macronuclear spermatozoa syndrome and its phenotypic variants: a form of teratozoospermia
Andrologie volume 18, pages 46–49 (2008)
Resume
Les tératozoospermies monomorphes reflètent une anomalie de structure des spermatozoïdes rare, mais sont souvent source de discussion lorsqu’il faut envisager une prise en charge thérapeutique. Nous proposons donc de faire le point des données actuelles de la littérature concernant le syndrome des spermatozoïdes macrocéphales et ses variants.
D’un point de vue pratique, en dehors de la forme homogène du syndrome, l’assistance médicale à la procréation (AMP) peut être proposée. Après évaluation des taux d’anomalies chromosomiques dans les spermatozoïdes de ces patients, une discussion multidisciplinaire et une information claire du couple sont nécessaires avant toute prise en charge en AMP.
Abstract
Macronuclear spermatozoa is a rare sperm defect, but always raises problems in the context of assisted reproductive technology (ART). The authors propose a review of the macronuclear spermatozoa syndrome and its phenotypic variants. In practice, ART can be proposed except in the homogeneous form of this sperm defect. Evaluation of chromosomal abnormality rates in the spermatozoa of these patients must be performed, followed by multidisciplinary discussion and clear information of the patients prior to ART.
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Metzler-Guillemain, C., Achard, V., Mercier, G. et al. Une forme de tératozoospermie monomorphe: Le syndrome des spermatozoïdes macrocéphales et ses variants. Androl. 18, 46–49 (2008). https://doi.org/10.1007/BF03040379
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DOI: https://doi.org/10.1007/BF03040379