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  • La Part du Mâle dans les Avortements Spontanés à Répétition
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Anomalies génétiques et avortements spontanés à répétition: la part de l’homme

Recurrent pregnancy losses and genetic abnormalities: paternal effect

Andrologie volume 6, pages 24–30 (1996)Cite this article

Resume

Sur le plan cytogénétique, la séléction embryonnaire des oeufs anormaux lors du développement in utero concerne aussi bien les aberrations formées lors des accidents meiotiques paternels que maternels. Ce phénomène est plus difficile à apprécier dans le cadre de la transmission d’une mutation génique délétère pour l’oeuf.

Abstract

Cytogeneticaly, in utero selection of chromosomaly abnormal embryos is well documented. There is no evidence of viability difference when the anomaly resulted from a paternal or maternal meiotic event, except for triploïdie.

There is no biological evidence of specific genomic mutation in spermatozoa responsible of early pregnancy wastage. However, this hypothesis can not be excluded

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  1. Laboratoire de Biologie de la Reproduction et de Cytogénétique CHU d’Amiens, 124 rue Camille Desmoulins, 80000, Amiens

    F. Thepot

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Thepot, F. Anomalies génétiques et avortements spontanés à répétition: la part de l’homme. Androl. 6, 24–30 (1996). https://doi.org/10.1007/BF03035065

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Basic and Clinical Andrology

ISSN: 2051-4190