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Incidence du cancer du testicule au niveau mondial

Worldwide incidence of testicular cancer

Résumé

Bien que le cancer du testicule fasse partie des tumeurs rares, il représente la tumeur la plus fréquente de l’homme jeune. Dans le monde, les pays européens, l’Amérique du Nord, l’Australie et la Nouvelle-Zélande montrent une forte incidence du cancer du testicule. Les données recueillies dans les pays en voie de développement sont encore très parcellaires, mais elles semblent confirmer que les hommes africains et asiatiques ont une incidence du cancer du testicule plus faible que les hommes caucasiens. Cette incidence paraît augmenter depuis le début du siècle dans les pays occidentaux avec une accentuation de cette tendance depuis les années 50. L’augmentation de l’incidence affecte particulièrement la classe d’âge des adolescents et des hommes jeunes. Les raisons de cette variation et de l’augmentation de l’incidence du cancer du testicule constatée dans de nombreux pays restent inconnues, bien que de forts soupçons pèsent sur des facteurs environnementaux, qui pourraient également retentir sur la fertilité masculine.

Abstract

Testicular cancer (TC) is the commonest malignancy in men aged 20 to 34 years. We reviewed the statistical sources of the IARC, and summarized the published studies on the increasing incidence rates of TC in the world.

We observed a variation of incidence rates according to the geographical situation. The majority of industrialized countries, North-America, Europe, and Oceania showed higher incidence rates than Asian or African countries. Nevertheless, surprising differences in TC incidence rates were observed between neighboring countries and also between different regions in the same country. Substantial differences in TC incidence were also observed between ethnic groups.

A clear trend towards an increase in TC incidence over the last decades was revealed. The increase in TC incidence was associated with a strong birth cohort effect in the USA, and also in European countries.

Previous studies have not been able to explain the variation of worldwide incidence rates and its increase. Although male reproductive abnormalities assumed to be related to exposure to high levels of endogenous oestrogens during pregnancy, further studies are required before any conclusions can be drawn.

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Correspondence to Tomohiro Matsuda.

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Matsuda, T., Huyghe, E. & Thonneau, P. Incidence du cancer du testicule au niveau mondial. Androl. 12, 149–155 (2002). https://doi.org/10.1007/BF03034961

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Mots clés

  • cancer du testicule
  • incidence
  • épidémiologie

Keywords

  • Testicular cancer
  • incidence
  • epidemiology
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