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Infections génito-urinaires et infécondité masculine: conséquences, diagnostic et traitement

Genitourinary infections and male infertility: impact, diagnosis and treatment

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Plusieurs études expérimentales et cliniques ont tenté d’expliquer le rôle des infections du tractus uro-génital sur la fonction reproductrice du sperme, dont des études récentes qui ont essayé de mettre en évidence l’effet néfaste des infections sur la mobilité en particulier, et peut-être sur les paramètres morphologiques des spermatozoïdes humains.

Dans la présente revue, nous avons essayé d’expliquer les différents points de vue et théories des divers types d’infections génito-urinaires (épididymite, orchite, infection des glandes accessoires mâles (IGAM), prostatite et urétrite) qui ont une influence directe sur les valeurs reproductives normales du sperme humain à la fois à travers les bactéries et par les processus inflammatoires. En outre, les infections peuvent être à l’origine d’auto-anticorps contre les spermatozoïdes.

Abstract

Several experimental and clinical studies have tried to explain the role of genitourinary tract infections on the reproductive function of semen, including recent studies that tried to reveal the negative impact of infections on mobility, in particular, and possibly on the morphological parameters of human spermatozoa.

In this review, we attempt to explain the different viewpoints and theories of the various types of genitourinary infections (epididymitis, orchitis, MAGI, prostatitis and urethritis) with a direct impact on normal reproductive values of human semen via the bacteria themselves and via the inflammatory processes. Infections may also be the source of autoantibodies directed against spermatozoa.

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Correspondence to Wolfgang Weidner.

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Tajjour, M., Weidner, W. Infections génito-urinaires et infécondité masculine: conséquences, diagnostic et traitement. Androl. 16, 109–124 (2006) doi:10.1007/BF03034842

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Key words

  • male infertility
  • genitourinary infection
  • MAGI

Mots clés

  • infécondité masculine
  • infection génitourinaire
  • IGAM