- Génétique et Infertilités
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Aspects génétiques de l'infertilité
Genetic aspects of infertility
Andrologie volume 9, pages 329–332 (1999)
Résumé
La fertilité d'un couple dépend pour partie de la qualité de la gamétogenèse qui comporte les divisions méiotiques et les phénomènes de différenciation aboutissant à la production de gamètes mûrs. Ces phénomènes sont placés sous le contrôle de nombreux gènes dont la plupart restent à identifier. La fertilité féminine est liée à la fécondabilité d'une unique cellule produite au cours du cycle, alors que la fertilité masculine dépend de la fonctionnalité d'une population hétérogène de spermatozoïdes. Il existe un faisceau d'arguments scientifiques en faveur de l'absence de corrélation entre la fonctionnalité d'un spermatozoïde et le génome haploïde qu'il v'hicule.
The fertility of a couple is partially related to the quality of gametogenesis, it includes meiotic divisions as well as differenciation processes leading to the formation of mature gametes. These phenomenona are under genomic control but most of their specific genes are still unknown. Female fertility depends on the fecundability of a unique cell produced during a cycle in contrast male fertility is conditionned by the fertilizing ability of a large population of highly heterogenous sperm. Several arguments are in favor of the absence of correlation between the fertilizing ability of a sperm and its genetic content.
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Sele, B. Aspects génétiques de l'infertilité. Androl. 9, 329–332 (1999). https://doi.org/10.1007/BF03034805
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DOI: https://doi.org/10.1007/BF03034805