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L’agenesie bilaterale congenitale des deferents a l’heure de I’ICSI

Congenital bilateral absence of the vas deferens at the present time of ICSI

Resume

L’agénésie bilatérale congénitale des déférents est l’anomalie la plus fréquente des voies génitales masculines. Le diagnostic est clinique, le bilan spermiologique associe azoospermie, hypospermie, pH acide, marqueurs épididymaires bas. Le bilan morphologique recherche une anomalie des vésicules séminales et une agénésie rénale. Une mutation du gène CFTR est retrouvée dans plus de 70% des cas. Un conseil génétique s’impose avant toute aide médicale à la procréation. Les résultats de l’ICSI avec sperme prélevé chirurgicalement sont les mêmes que dans les autres causes d’azoospermies excrétoires.

Abstract

Congenital bilateral absence of the vas deferens is the most frequent abnormality of the male genital tract Diagnosis is clinical. Seminal patterns associate azoospermia, hypospermia, low PH, low seminal markers. Transrectal and renal ultrasonography search for abnormalities of the seminal vesicles and renal agenesis. Mutations of CFTR gene are found in more than 70% of all cases. Genetic council is necessary before ICSI. Results of ICSI with micro-epididymal sperm aspiration are the same as in the other cases of azoospermia.

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Rigot, J.M., Gervais, R., Dumur, V. et al. L’agenesie bilaterale congenitale des deferents a l’heure de I’ICSI. Androl. 8, 57–60 (1998). https://doi.org/10.1007/BF03034762

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