- Cancer du Testicule
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Augmentation de l’incidence du cancer du testicule: état de la question
Increase of incidence rates of testis cancer
Andrologie volume 10, pages 302–311 (2000)
Resume
Bien que le cancer du testicule fasse partie des tumeurs rares, il représente la tumeur la plus fréquente de l’homme jeune. Son incidence parait augmenter depuis le début du siècle dans les pays occidentaux, avec une accentuation de cette tendance depuis les années 50. L’augmentation de l’incidence affecte particulièrement la classe d’âge des adolescents et des hommes jeunes. Les données recueillies dans les pays en voie de développement sont encore très parcellaires, mais elles semblent confirmer que les hommes de race noire et asiatique aient une incidence du cancer du testicule plus faible que les hommes de race blanche. Les raisons de l’augmentation de l’incidence du cancer du testicule constatée dans de nombreux pays restent inconnues, bien que de forts soupçons pèsent sur des facteurs environnementaux, qui pourraient également retentir sur la fertilité masculine, et d’autre tumeurs de la sphère génitale (sein, endomètre, prostate).
Abstract
Although germ cell cancer is rare (about 1% of cancers in male), it is the commonest cancer in young man. Many studies in Europe, Northern America and Australia show that incidence rates of testis cancer are climbing. In Northern Europe and America, where cancer registration exist since the fifties, it is showed that overall age-adjusted incidence rate of testis cancer has increased more than 3 fold during the past 50 years. This increase affect particularly teenagers and young men. The increase of incidence rates is less documented in under developed countries but recent studies seem to confirm an increase of incidence rates in many parts of the world, even if testis cancer remain rarer in non Caucasian populations.
Etiologies of a such increase are still unknown, but arguments point in view a possible relation between environmental hormone disrupters and many hormonodependent cancers, such as testicular neoplasm, the cancer of the breast or even prostate cancer. Epidemiological studies with large sample size are needed to identify risk factors responsible for the increase of incidence rates of testis cancer.
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Huyghe, E., Thonneau, P.F. Augmentation de l’incidence du cancer du testicule: état de la question. Androl. 10, 302–311 (2000). https://doi.org/10.1007/BF03034754
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DOI: https://doi.org/10.1007/BF03034754