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Anomalies génétiques de la spermatogenèse

Genetic disorders of spermatogenesis

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Le rôle important des anomalies génétiques responsables d’infertilité masculine est de plus en plus clairement reconnu. Des progrès considérables ont été réalisés aux cours des dernières années aussi bien dans la description clinique des formes génétiques d’infertilité masculine que dans la recherche des gènes responsables et de leurs mutations. Nous présentons une revue des connaissances actuelles concernant les anomalies génétiques régulièrement responsables d’infertilité masculine.


The important role of genetic abnormalities in the causation of human male infertility is increasingly recognized. Considerable progress has been achieved over the past years both in the clinical delineation of genetic forms of male infertility and in the characterization of the responsible genes and their mutations. We review the current state of knowledge on genetic disorders where male infertility is a major and regular feature.


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Meschede, D. Anomalies génétiques de la spermatogenèse. Androl. 10, 271–273 (2000).

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Mots clés

  • anomalies chromosomiques
  • infertilité familiale
  • génétique
  • maladies monogéniques
  • spermatogenèse

Key words

  • chromosomal anomalies
  • familial infertility
  • genetics
  • monogenic disorders
  • spermatogenesis