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Traitements anticancereux et spermatogenese. Moyens de protection

Antineoplasic treatments and spermatogenesis. Means of protection

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Abstract

A litterature review reports the spermatotoxicity of the different antineoplasic therapies. Recovery of spermatogenesis after completion of most toxic treatments and its delay are individually unforeseen. Pregnancies have occured after treatment with very low sperm counts. These pregnancies ask the question of mutagenicity of antineoplasic treatments. The means of protection seem presently very poor.

Resume

Une revue de la littérature fait le point de la spermatotoxicité des différentes thérapeutiques anticancéreuses. Après les traitements réputés stérilisants, la récupération de la fonction gamétogénétique et son délai s’avèrent imprévisibles au plan individuel. Des grossesses ont été obtenues après traitement anticancéreux avec des chiffres de numération spermatique très bas. Celles-ci posent le problème de la mutagénicité des thérapeutiques anticancéreuses. Les moyens de protection s’avèrent actuellement limités.

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Author information

Correspondence to Françoise Grob-Menendez.

Additional information

présenté aux 4èmes Journées d’Andrologie de l’Hôpital Saint-Antoine le 15 Juin 1992

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Grob-Menendez, F., Marmor, D. Traitements anticancereux et spermatogenese. Moyens de protection. Androl. 2, 97–99 (1992) doi:10.1007/BF03034683

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Key-words

  • spermatotoxicity
  • radiotherapy
  • chemotherapy

Mots clés

  • spermatotoxicité
  • radiothérapie
  • chimiothérapie