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Epidémiologie de la dysfonction érectile (2ème partie). Facteurs de risque

Epidemiology of erectile dysfunction (part 2). Risk factors

Andrologie volume 12, pages 323–331 (2002)Cite this article

Resume

Les enquêtes épidémiologiques réalisées dans la population générale de nombreux pays et l’étude de populations ciblées (dont un exemple est l’enquête réalisée en France par Leriche et Jaudinot chez 7469 patients diabétiques, hypertendus ou les deux) ont mis en évidence de nombreux facteurs de risque de dysfonction érectile: diabète, hypertension artérielle, tabagisme, dyslipidémie, maladies cardio-vasculaires, troubles psychologiques, certains médicaments, insuffisance rénale chronique, facteurs liés au statut socio-économique et au mode de vie, obésité, symptômes du bas appareil urinaire, mauvais état général et cyclisme.

Les facteurs de risque cardio-vasculaires sont prédictifs de dysfonction érectile et actuellement la dysfonction érectile est souvent considérée comme une entité de lamaladie vasculaire ouendothéliale.

De nouvelles études sont nécessaires pour préciser les mécanismes physiopathologiques de certains facteurs de risque et l’intérêt éventuel de mesures de prévention.

Abstract

Epidemiological studies in the general population or target populations in several countries in the world have revealed a large number of risk factors for erectile dysfunction: diabetes mellitus, hypertension, smoking, dyslipidaemia, cardiovascular diseases, psychological disorders, certain medications, chronic renal failure, socioeconomic factors and lifestyle, obesity, lower urinary tract symptoms, poor health and bicycling.

Cardiovascular risk factors are predictors of erectile dysfunction and erectile dysfunction is now considered to be a manifestation of vascular disease.

Further studies are necessary to establish the pathophysiological mechanisms of certain risk factors and the possible value of preventive measures.

References

  1. ANSONG K.S., LEWIS C., JENKINS P., BELL J.: Epidemiology of erectile dysfunction: a community-based study in rural New York State. Ann. Epidemiol., 2000, 10: 293–296.

    Article  PubMed  CAS  Google Scholar 

  2. ARAUJO A.B., JOHANNES C.B., FELDMAN H.A., DERBY C.A., McKiNLAY J.B.: Relation between psychosocial risk factors and incident erectile dysfunction: prospective results from the Massachusetts Male Aging Study. Am. J. Epidemiol., 2000, 152: 533–541.

    Article  PubMed  CAS  Google Scholar 

  3. AYTAC I.A., ARAUJO A.B., JOHANNES C.B., KLEINMAN K.P., McKINLAY J.B.: Socioeconomic factors and incidence of erectile dysfunction: findings of the longitudinal Massachussetts Male Aging Study. Soc. Sci. Med., 2000, 51: 771–778.

    Article  PubMed  CAS  Google Scholar 

  4. BARKSDALE J.D., GARDNER S.F.: The impact of first-line antihypertensive drugs on erectile dysfunction. Pharmacotherapy, 1999, 19: 573–581.

    Article  PubMed  CAS  Google Scholar 

  5. BEHR-ROUSSEL D., CHAMIOT-CLERC P., BERNABE J. et al.: L’hypertension artérielle: facteur de risque de l’insuffisance érectile — 1ère démonstration expérimentale. Communication au 96e Congrès de l’Association Française d’Urologie, 20–23 novembre 2002, Paris.

  6. BORTOLOTTI A., FEDELE D., CHATENOUD L., et al.: Cigarette smoking: a risk factor for erectile dysfunction in diabetics. Eur. Urol., 2001, 40: 392–396.

    Article  PubMed  CAS  Google Scholar 

  7. BRAUN M., WASSMER G., KLOTZ T., REIFENRATH B., MATHERS M., ENGELMAN U.: Epidemiology of erectile dysfunction: results of the ‘Cologne Male Survey’. Int. J. Impot. Res., 2000, 12: 305–311.

    Article  PubMed  CAS  Google Scholar 

  8. BURCHARDT M., BURCHARDT T., BAER L. et al.: Hypertension is associated with severe erectile dysfunction. J. Urol., 2000, 164: 1188–1191.

    Article  PubMed  CAS  Google Scholar 

  9. CARSON C.C., PATEL M.P.: The epidemiology, anatomy, physiology, and treatment of erectile dysfunction in chronic renal failure patients. Adv. Ren. Replace. Ther., 1999, 6: 296–309.

    PubMed  CAS  Google Scholar 

  10. CERQUEIRA J., MORAES M., GLINA S.: Erectile dysfunction: prevalence and associated variables in patients with chronic renal failure. Int. J. Impot. Res., 2002, 14: 65–71.

    Article  PubMed  CAS  Google Scholar 

  11. CHEW K.K., EARLE C.M., STUCKEY B.G., JAMROZIK K., KEOGH E.J.: Erectile dysfunction in general medicine practice: prevalence and clinical correlates. Int. J. Impot. Res., 2000, 12: 41–45.

    Article  PubMed  CAS  Google Scholar 

  12. CHUNG W.S., SOHN J.H., PARK Y.Y.: Is obesity an underlying factor in erectile dysfunction? Eur. Urol., 1999, 36: 68–70.

    Article  PubMed  CAS  Google Scholar 

  13. DERBY C.A., BARBOUR M.M., HUME A.L., McKINLAY J.B.: Drug therapy and prevalence of erectile dysfunction in the Massachusetts Male Aging Study cohort. Pharmacotherapy, 2001, 21: 676–683.

    Article  PubMed  CAS  Google Scholar 

  14. DERBY C.A., MOHR B.A., GOLDSTEIN I., FELDMAN H.A. JOHANNES CB, McKINLAY JB: Modifiable risk factors and erectile dysfunction: can lifestyle changes modify risk. Urology, 2000, 56: 302–306.

    Article  PubMed  CAS  Google Scholar 

  15. FEDELE D., COSCELLI C., CUCINOTTA D. et al.: Incidence of erectile dysfunction in Italian men with diabetes. J. Urol., 2001, 166: 1368–1371.

    Article  PubMed  CAS  Google Scholar 

  16. FEDELE D., COSCELLI C., SANTEUSANIO F. et al.: Erectile dysfunction in diabetic subjects in Italy. Gruppo Italiano Studio Deficit Erettile nei Diabetici. Diabetes Care, 1998, 21: 1973–1977.

    Article  PubMed  CAS  Google Scholar 

  17. FELDMAN H.A., GOLDSTEIN L., HATZICHRISTOU D.G., KRANE R.J., McKINLAY J.B.: Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J. Urol., 1994, 151: 54–61.

    PubMed  CAS  Google Scholar 

  18. FELDMAN H.A., JOHANNES C.B., DERBY C.A. et al.: Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Prev. Med., 2000, 30: 328–338.

    Article  PubMed  CAS  Google Scholar 

  19. FRANKEL S.J., DONOVAN J.L., PETERS T.I. et al.: Sexual dysfunction in men with lower urinary tract symptoms. J. Clin. Epidemiol., 1998, 51: 677–685.

    Article  PubMed  CAS  Google Scholar 

  20. FRANZEN D., METHA A., SELFERT N., BRAUN M., HOPP H.W.: Effects of beta-blockers on sexual performance in men with coronary heart disease. A prospective, randomized and double blinded study. Int. J. Impot. Res., 2001, 13: 348–351.

    Article  PubMed  CAS  Google Scholar 

  21. GREENSTEIN A., CHEN J., MILLER H., MATZKIN H., VILLA Y., BRAF Z.: Does severity of ischemic coronary disease correlate with erectile function? Int. J. Impot. Res., 1997, 9: 123–126.

    Article  PubMed  CAS  Google Scholar 

  22. GRIMM R.H. Jr, GRANDITS G.A., PRINEAS R., et al.: Longterm effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS). Hypertension, 1997, 29: 8–14.

    PubMed  CAS  Google Scholar 

  23. GRUNBAUM A., KHALEEG-UR-REHMAN, CARRIER S.: Bicycling and erectile dysfunction: a review of the literature. J. Sex. Reprod. Med., 2002, 2: 75–79.

    Google Scholar 

  24. GUAY A.T., PEREZ J.B., HEAT G.J.: Cessation of smoking rapidly decreases erectile dysfunction. Endoc. Pract., 1998, 4, 23–26.

    CAS  Google Scholar 

  25. HAKIM L.S., GOLDSTEIN I.: Diabetic sexual dysfunction. Endocrinol. Metab. Clin. North Am., 1996, 25: 379–400.

    Article  PubMed  CAS  Google Scholar 

  26. JENSEN J., LENDORF A., STIMPEL H., FROST J., IBSEN H., ROSENKILDE P.: The prevalence and etiology of impotence in 101 male hypertensive outpatients. Am. J. Hypertens., 1999, 12: 271–275.

    Article  PubMed  CAS  Google Scholar 

  27. JOHANNES C., ARAUJO A.B., FELDMAN H.A., DERBY C.A., McKINLAY J.B.: Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts Male Aging Study. J. Urol., 2000, 163: 460–463.

    Article  PubMed  CAS  Google Scholar 

  28. KIM S.W., PAICK J., PARK D.W., CHAE I., OH B.: Potential predictors of asymptomatic ischemic heart disease in patients with vasculogenic erectile dysfunction. Urology, 2001, 58: 441–445.

    Article  PubMed  CAS  Google Scholar 

  29. KLEIN R., KLEIN B.E., LEE K.E., MOSS S.E., CRUICKS-HANKS K.J.: Prevalence of self-reproted erectile dysfunction in people with long-term IDDM. Diabetes Care, 1996, 19: 135–141.

    Article  PubMed  CAS  Google Scholar 

  30. LAUMANN E.O., PAIK A., ROSEN R.C.: Sexual dysfunction in the United States: prevalence and predictors. J.A.M.A., 1999, 281: 537–544.

    Article  PubMed  CAS  Google Scholar 

  31. LEE I.C., SURRIDGE D., MORALES A., HEATON J.P.: The prevalence and influence of significant psychiatric abnormalities in men undergoing comprehensive management of organic erectile dysfunction. Int. J. Impot. Res., 2000, 12: 47–51.

    Article  PubMed  CAS  Google Scholar 

  32. LERICHE A., JAUDINOT E.O., SOLESSE DE GENDRE A.: Enquête sur la prévalence des troubles de l’érection et leur prise en charge chez des patients à risque suivis en consultation de médecine générale. Communication au 94ème Congrès de l’Association française d’urologie, Paris, 15–19 Novembre 2000, Résumé 03.

  33. LEWIS R.W.: Epidemiology of erectile dysfunction. Urol. Clin. North Am., 2001, 28: 209–216.

    Article  PubMed  CAS  Google Scholar 

  34. McVAY K.T., CARRIER S., WESSELLS H.: Smoking and erectile dysfunction: evidence based analysis. J. Urol., 2001, 166: 1624–1632.

    Article  Google Scholar 

  35. MALAVAUD B., ROSTAING L., RISCHMANN P., SARRAMON J.P., DURAND D.: High prevalence of erectile dysfunction after renal transplantation. Transplantation, 2000, 69: 2121–2124.

    Article  PubMed  CAS  Google Scholar 

  36. MANNINO D.M., KLEVENS R.M., FLANDERS W.D.: Cigarette smoking: an independent risk factor for impotence? Am. J. Epidemiol., 1994, 140: 1003–1008.

    PubMed  CAS  Google Scholar 

  37. MARCEAU L., KLEINMAN K., GOLDSTEIN I., McKINLAY J.: Does bicycling contribute to the risk of erectile dysfunction? Results from the Massachusetts Male Aging Study (MMAS). Int. J. Impot. Res., 2001, 13: 298–302.

    Article  PubMed  CAS  Google Scholar 

  38. MARTIN-MORALES A., SANCHEZ-CRUZ J.J., SAENZ DE TEJADA I., RODRIGUEZ-VELA L., JIMENEZ-CRUZ J.F., BURGOS-RODRIGUEZ R.: Prevalence and independent risk factors for erectile dysfunction in Spain: results of the Epidemiologia de la Disfunction Erectil Masculina Study. J. Urol., 2001, 166: 569–574.

    Article  PubMed  CAS  Google Scholar 

  39. MEINHARDT W., KROPMAN R.F., VERMEIJ P., NIJEHOLT A.A., ZWARTENDIJK J.: The influence of medication on erectile function. Int. J. Impot. Res., 1997, 9: 17–26.

    Article  PubMed  CAS  Google Scholar 

  40. NETO A.F., DE FREITAS RODRIGUES M.A., SARAIVA FITTIPALDI J.A., MOREIRA E.D. Jr: The epidemiology of erectile dysfunction and its correlates in men with chronic renal failure on hemodialysis in Londrina, southern Brazil. Int. J. Impot. Res., 2002, 14 Suppl 2: 19–26.

    Article  Google Scholar 

  41. O’KANE P.D., JACKSON G.: Erectile dysfunction: is there silent obstructive coronary artery disease? Int. J. Clin. Pract., 2001, 55: 219–220.

    PubMed  CAS  Google Scholar 

  42. PARAZZINI F., MENCHINI FABRIS F., BORTOLLI A.: Frequency and determinants of erectile dysfunction in Italy. Eur. Urol., 2000, 37: 43–49.

    Article  PubMed  CAS  Google Scholar 

  43. PINNOCK C.B., STAPLETON A.M., MARSHALL V.R.: Erectile dysfunction in the community: a prevalence study. Med. J. Aust., 1999, 171: 353–357.

    PubMed  CAS  Google Scholar 

  44. ROSAS S.E., JOFFE M., FRANKLIN E. et al.: Prevalence and determinants of erectile dysfunction in hemodialysis patients. Kidney Int., 2001, 59: 2259–2266.

    PubMed  CAS  Google Scholar 

  45. SAIRAM K., KULINSKAYA E., BOUSTEAD G.B., HANBURY D.C., McNICHOLAS T.A.: Prevalence of undiagnosed diabetes mellitus in male erectile dysfunction. Brit. J. Urol. Int., 2001, 88: 68–71.

    CAS  Google Scholar 

  46. SCHACHTER M.: Erectile dysfunction and lipid disorders. Curr. Med. Res. Opin., 2000, 16 Suppl 1: 9–12.

    Article  Google Scholar 

  47. SIU S.C., LO S.K., WONG K.W., IP K.M., WONG Y.S.: Prevalence of and risk factors for erectile dysfunction in Hong Kong diabetic patients. Diabet. Med., 2001, 18: 732–738.

    Article  PubMed  CAS  Google Scholar 

  48. SULLIVAN M.E., MILLER M.A., BELL C.R. et al.: Fibrinogen, lipoprotein (a) and lipids in patients with erectile dysfunction. A preliminary study. Int. Angiol., 2001, 20: 195–199.

    PubMed  CAS  Google Scholar 

  49. SULLIVAN M.E., THOMPSON C.S., DASHWOOD M.R. et al.: Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease? Cardiovasc. Res., 1999, 43: 658–665.

    Article  PubMed  CAS  Google Scholar 

  50. TENGS T.O., OSGOOD N.D.: The link between smoking and impotence: two decades of evidence. Prev. Med., 2001, 32: 447–526.

    Article  PubMed  CAS  Google Scholar 

  51. WEI M., MACERA C.A., DAVIS D.R., HORNUNG C.A., NANKIN H.R., BLAIR S.N.: Total cholesterol and high density lipoprotein cholesterol as important predictors of erectile dysfunction. Am. J. Epidemiol., 1994, 140: 930–937.

    PubMed  CAS  Google Scholar 

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  1. Service d’Uro-Andrologie, CHR La Source, BP 6709, 45067, ORLEANS Cedex 2

    Dominique Delavierre

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Delavierre, D. Epidémiologie de la dysfonction érectile (2ème partie). Facteurs de risque. Androl. 12, 323–331 (2002). https://doi.org/10.1007/BF03034649

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