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Fécondation assistée par micro injection des spermatides: Etat des lieux et questions posées

ICSI with spermatid injection: a review and questions

Andrologie volume 8, pages 362–372 (1998)Cite this article

Resume

L'injection intracytoplasmique par ICSI d'un gamète immature (spermatide) a été réalisée dans plusieurs espèces animales (souris, hamster, lapin, et bovin), ainsi que chez l'homme. Le recours à des spermatides pour ICSI concerne des patients chez lesquels aucun spermatozoïde n'a été observé dans l'éjaculat ou dans le testicule. Vanderzwalmen et al (1995) rapportaient chez l'homme la fécondation d'ovocytes et le clivage embryonnaire par l'injection en ICSI de spermatides allongées. Cela a été confirmé par l'obtention de quelques naissances à la suite de l'injection ovocytaire de spermatides rondes ou allongées extraites de l'éjaculat ou du testicule. Mais, aujourd'hui, l'utilisation de spermatides en ICSI demeure très controversée. Le succès de I'ICSI avec une spermatide, son identification, ainsi que les problèmes posés, sont l'object de cette revue.

Abstract

In order to treat male infertility, since 5 years ago, intracytoplasmic sperm injection (ICSI) represents a new therapeutic approach of different forms of male sterility including obstructive and spermatogenic failure azoospermia. This paper reviews the use of ICSI with round or elongated spermatids.

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Authors and Affiliations

  1. Centre de Fécondation in Vitro, Service de Biologie et Génétique de la Reproduction, Hôpital A. Béclère, 157 rue de la Porte-de-Trivaux, 92141, Clamart

    S. Hamamah, C. Conord & N. Frydman

  2. Service de Gynécologie-Obstétrique et de Médecine de la Reproduction, CHU de Grenoble, Grenoble, France

    J -M Ayoubi

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  1. S. Hamamah
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  2. C. Conord
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  3. J -M Ayoubi
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  4. N. Frydman
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Hamamah, S., Conord, C., Ayoubi, J.M. et al. Fécondation assistée par micro injection des spermatides: Etat des lieux et questions posées. Androl. 8, 362–372 (1998). https://doi.org/10.1007/BF03034573

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Basic and Clinical Andrology

ISSN: 2051-4190