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  • Le Laboratoire: Diagnostic, Explorations Fonctionnelles
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Mise en évidence des cellules inflammatoires dans le sperme

Inflammatory cells in semen

Andrologie volume 5, pages 548–554 (1995)Cite this article

Resume

Une concentration élevée de cellules rondes dans un sperme réduit la fécondance. Ces cellules peuvent être des cellules germinales immatures résultant d'une souffrance testiculaire accompagnée par la tératospermie, ou des polynucléaires s'ils sont peroxydases positifs. Il arrive que ni la tératospermie, ni la réaction à la peroxydase n'expliquent le nombre élevé de ces cellules. Pour ces spermes, nous avons utilisé la coloration de l'estérase non spécifique pour la recherche des macrophages, des plasmocytes et des lymphocytes. Ces trois types de cellules ont été retrouvés dans certains spermes non leucospermiques. Ce qui reflète une infection chronique en cours d'évolution. Les macrophages, les lymphocytes et les plasmocytes ont également été retrouvés dans certains spermes leucospermiques. La présence des macrophages est corrélée avec celle des plasmocytes (r=0,65 — p=0,01) et des lymphocytes (r=0,56 — p=0,05). Entre les plasmocytes et les lymphocytes la corrélation est plus importante (r=0,91 — p=0,001).

Abstract

A high level of round cells in semen decreases the fertility capacity. These cells can be either immature germinal cells from testicular disorders characterized by teratospermia, or polymorphonuclear cells if they are peroxidase positive. However it often happens that neither teratospermia nor peroxidase reaction can explain the high proportion of round cells. For these semen we have used the nonspecific esterase staining to search for macrophages, plasma-cells and lymphocytes. These three types of cells were detected in certain non-leucospermic semen which reflects a chronic infection in development. Also these cells, macrophages, plasma-cells and lymphocytes were found in some leucospermic semen samples. If we considere the populations leucospermic and non leucospermic together, macrophages are correlated — with plasma-cells (r=0,65 — p=0,01) and with lymphocytes (r=0,56 — p=0,05). The correlation between plasma-cells and lymphocytes was more important (r=0,91 — p=0,001).

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Authors and Affiliations

  1. Groupe de Recherche en Andrologie, 11, rue Humann Faculté de médecine, Strasbourg

    M. Belmekki, C. Cranz & A. Clavert

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  1. M. Belmekki
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  2. C. Cranz
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  3. A. Clavert
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Belmekki, M., Cranz, C. & Clavert, A. Mise en évidence des cellules inflammatoires dans le sperme. Androl. 5, 548–554 (1995). https://doi.org/10.1007/BF03034541

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Basic and Clinical Andrology

ISSN: 2051-4190