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  • La Fecondation par Micro-Injection des Spermatides: Problemes Resolus, Questions Posees
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La spermatide, cette méconnue

The spermatid, an unrecognized germ cell

Resume

L'usage de la micro-insémination ovocytaire de spermatides rondes ou allongées, dans certains cas d'infertilité masculine, nécessite de reconsidérer la séquence des modifications morphologiques et fonctionnelles qui surviennent durant la spermiogenèse. Cet article a pour objet de passer en revue les acquisitions essentielles sur la morphogenèse des spermatides, l'expression du génome au cours de la différenciation des spermatozoïdes et les interactions cellulaires entre les spermatides elles-mêmes et entre les spermatides et les cellules de Sertoli. Il apparaît que les spermatides rondes et les spermatides allongées représentent deux classes de cellules structuralement et fonctionnellement différentes. Une interrogation demeure: sur quels critères peut-on affirmer qu'une spermatide ronde est fonctionnellement normale quand il y a arrêt ou altération de la spermiogenèse?

Abstract

The use of microinsemination of round or elongated spermatids into ovocytes, in certain cases of male infertility, requires re-examination of the sequence of morphological and functional changes that occur throughout spermiogenesis. This paper reviews essential findings on morphogenesis of spermatids, genome expression during sperm differentiation and cellular interactions between spermatids themselves and between spermatids and Sertoli cells. Round and elongated spermatids appear to represent two classes of structuraly and functionnaly different cells. One question remains: on what criteria can one claim that a round spermatid functions normally when spermiogenesis is blocked or impaired?

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Dadoune, J.P. La spermatide, cette méconnue. Androl. 7, 22–33 (1997). https://doi.org/10.1007/BF03034517

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  • DOI: https://doi.org/10.1007/BF03034517

Mots clés

  • spermatides
  • micro-insémination ovocytaire

Key words

  • spermatids
  • ovocyte microinsemination