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  • Cancer du Testicule
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Le carcinome in situ du testicule — un précurseur du cancer à cellule germinale. Revue de la pathogenèse et aspects cliniques

Carcinoma in situ of the testis — a precursor of germ cell cancer. A review of pathogenesis and clinical aspects

Andrologie volume 10, pages 181–193 (2000)Cite this article

Résumé

Les tumeurs à cellule germinale du testicule diffèrent des autres tumeurs solides en ce qui concerne leur épidémiologie et certains aspects biologiques. La pathogenèse de ces tumeurs malignes est encore inconnue à l’exception du fait que tous les types de tumeurs à cellule germinale des adultes jeunes proviennent d’un précurseur commun: la cellule ducarcinome in situ (CIS). Une très forte augmentation récente de l’incidence du cancer du testicule suggère que des facteurs environnementaux, plus particulièrement ceux qui agissent au cours du développement, pourraient jouer un rôle. Cette revue résume les caractéristiques biologiques les plus importantes du CIS du testicule et discute sa prise en charge clinique.

Abstract

Testicular germ cell tumors are different than other solid tumours with regard to their epidemiology and certain biological aspects. Pathogenesis of this malignancy remains unknown with the exception that all types of germ cell tumours in young adults originate from a common precursor:carcinoma in situ (CIS) cell. A recent dramatic increase in the incidence of testicular cancer suggests that environmental factors, especially those acting during development, may play a role. This review summarises the most important biological features of testicular CIS and discusses clinical management.

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  1. Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Section GR-5064, 9 Blegdamsvej, DK-2100, Copenhagen, Denmark

    E. Rapjert-De Meyts, A. Giwercman & N. E. Skakkebaek

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  1. E. Rapjert-De Meyts
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Rapjert-De Meyts, E., Giwercman, A. & Skakkebaek, N.E. Le carcinome in situ du testicule — un précurseur du cancer à cellule germinale. Revue de la pathogenèse et aspects cliniques. Androl. 10, 181–193 (2000). https://doi.org/10.1007/BF03034370

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ISSN: 2051-4190