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Les tests d’exploration de la fecondance des spermatozoides en vue d’une fecondation assistee

Fertilizing ability testing in assisted fertilization

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Abstract

It is now possible to evaluate each specific function of the spermatozoon by diagnostic testing. These tests, which are correlated with the outcome of male factor IVF, are unnecessary in routine practice. However, they are highly relevant in cases of repeated fertilization failure at IVF, allowing the detection of a specific defect in one of the component processes of fertilization which facilitates the decision as to whether to either abandon further attempts or continue with assisted fertilization treatment. Such testing must allow selection of the appropriate sperm preparation and microinjection methods and also clarify the indications, contraindications and risks of these techniques which, for the present, remain in the research domain

Resume

Il est possible actuellement d’évaluer chaque fonction spécifique du spermatozoîde à l’aide de tests d’exploration. Ces tests, bien que corrélés aux résultats de la FIV d’indication masculine, ne sont pas nécessaires en pratique courante. Par contre ils prennent toute leur signification en cas d’échecs répétés en FIV afin de rechercher une anomalie spécifique d’une des étapes de la fécondation et pour décider l’arrêt définitif des tentatives ou le recours éventuel à une fécondation assistée. Ils devraient permettre de choisir la technique de préparation et de microinjection du ou des spermatozoïdes et de clarifier les indications, les contreindications et risques de ces techniques qui restent pour l’instant du domaine de l’expérimentation.

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Correspondence to Patrick Fénichel.

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Fénichel, P. Les tests d’exploration de la fecondance des spermatozoides en vue d’une fecondation assistee. Androl. 2, 58–60 (1992) doi:10.1007/BF03034220

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Key words

  • Assisted fertilization
  • gametic interaction
  • videomicrography
  • hemi
  • zona test
  • acrosome reaction
  • hamster test
  • nuclear decondensation

Mots clés

  • Fécondation assistée
  • interaction gamétique
  • videomicrographie assistée par ordinateur
  • hémizona test
  • réaction acrosomique
  • hamster test
  • décondensation nucléaire