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Les proteines majeures de la secretion prostatique

Major prostatic secretory proteins


Human prostatic secretion contains only a few major proteins among which one finds albumin, acid phosphatase, prostate specific antigen (PSA), prostatic secretory protein of 94 amino acids (PSP94), Zn-α2-glycoprotein and α1-acid glycoprotein. The roles of most of these proteins are not entirely known. However, PSA has been shown to contribute to the hydrolysis of the seminal coagulum proteins. Probable roles for the other components include modifications of the properties of spermatozoa surface and control of inflammatory responses in male and female urogenital tracts.


La sécrétion prostatique humaine ne contient que quelques protéines majeures parmi lesquelles on retrouve l’albumine, la phosphatase acide, l’antigène spécifique à la prostate (PSA), la protéine de sécrétion de 94 acides aminés (PSP94), la Zn-α2-glycoprotéine et l’α1-glycoprotéine. Le rôle de la plupart de ces protéines n’est pas entièrement connu. On sait toutefois que le PSA contribue à l’hydrolyse des protéines du coagulum formé lors de l’éjaculation. Les rôles probables des autres constituants incluent l’altération des propriétés de surface du spermatozoïde et le contrôle des réponses inflammatoires dans les tractus urogénitaux de l’homme et de la femme.


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Dubé, J.Y. Les proteines majeures de la secretion prostatique. Androl. 1, 56–58 (1991).

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