Parameter | Organic hypogonadism n = 53 | Functional hypogonadism n = 165 | Eugonadism n = 182 | p (CSQ) | OrH vs. FuH | OrH vs. EuG | FuH vs. EuG | |
---|---|---|---|---|---|---|---|---|
n (%) | ||||||||
ED (prevalence) | 53 (100%) | 165 (100%) | 168 (92.3%) | 0.0002 | 0.843 | 0.048 | < 0.001 | |
ED (severity) | ||||||||
Severe | 7 (13.2%) | 27 (16.4%) | 1 (0.6%) | < 0.0001 | 0.722 | < 0.001 | < 0.001 | |
Moderate | 19 (35.8%) | 64 (38.8%) | 15 (8.2%) | |||||
Mild-to-moderate | 25 (47.2%) | 73 (44.2%) | 123 (67.6%) | |||||
Mild | 2 (3.8%) | 1 (0.6%) | 29 (15.9%) | |||||
Normal | 0 (0%) | 0 (0%) | 14 (7.7%) | |||||
Age classes, years | ||||||||
< 50 | 36 (67.9%) | 19 (11.9%) | 32 (17.6%) | < 0.0001 | < 0.001 | < 0.001 | < 0.001 | |
50–59 | 11 (20.8%) | 38 (23%) | 49 (26.9%) | |||||
60–69 | 5 (9.4%) | 47 (28.5%) | 75 (41.2%) | |||||
70+ | 1 (1.9%) | 61 (37%) | 26 (14.3%) | |||||
Comorbidities included in the CCI | ||||||||
1 point | Cerebrovascular disease | 0 (0%) | 18 (10.9%) | 11 (6%) | 0.0200 | - | - | - |
Chronic lung disease | 3 (5.7%) | 43 (26.1%) | 37 (20.3%) | 0.0061 | 0.010 | 0.030 | 0.347 | |
Congestive heart failure | 2 (3.8%) | 32 (19.4%) | 12 (6.6%) | 0.0002 | 0.010 | 0.703 | < 0.001 | |
Connective tissue disease | 1 (1.9%) | 8 (4.9%) | 11 (6%) | 0.4707 | - | - | - | |
Dementia | 0 (0%) | 5 (3%) | 5 (2.8%) | 0.6143a | - | - | - | |
Diabetes without end-organ damage | 10 (18.9%) | 47 (28.5%) | 80 (44%) | 0.0004 | 0.327 | < 0.001 | < 0.001 | |
Mild liver disease | 21 (36.6%) | 104 (63%) | 72 (39.6%) | < 0.0001 | < 0.001 | 0.990 | < 0.001 | |
Myocardial infarction | 0 (0%) | 38 (23%) | 29 (15.9%) | 0.0004 | < 0.001 | < 0.001 | 0.227 | |
Peripheral vascular disease | 0 (0%) | 20 (12.1%) | 16 (8.8%) | 0.0271 | 0.020 | 0.040 | 0.594 | |
Ulcer | 0 (0%) | 28 (17%) | 12 (6.6%) | 0.0002 | < 0.001 | 0.139 | < 0.001 | |
2 points | Any tumor | 3 (5.7%) | 21 (12.7%) | 27 (14.8%) | 0.2116 | - | - | - |
Diabetes with end-organ damage | 1 (1.9%) | 91 (55.2%) | 52 (28.6%) | < 0.0001 | < 0.001 | < 0.001 | < 0.001 | |
Hemiplegia | 0 (0%) | 1 (0.6%) | 1 (0.6%) | 1.0000a | - | - | - | |
Leukemia | 0 (0%) | 1 (0.6%) | 3 (1.7%) | 0.7879a | - | - | - | |
Lymphoma | 0 (0%) | 1 (0.6%) | 2 (1.1%) | 1.0000a | - | - | - | |
Moderate or severe kidney disease | 0 (0%) | 46 (27.9%) | 20 (11.1%) | < 0.0001 | < 0.001 | 0.010 | < 0.001 | |
3 points | Moderate or severe liver disease | 2 (3.8%) | 5 (3%) | 6 (3.3%) | 0.9643 | - | - | - |
6 points | AIDS | 0 | 0 | 0 | - | |||
Metastatic solid tumor | 1 (1.9%) | 2 (1.2%) | 5 (2.8%) | 0.6200a | - | - | - | |
Other data | ||||||||
Arterial hypertension | 22 (41.5%) | 152 (92.1%) | 145 (79.7%) | < 0.0001 | < 0.001 | < 0.001 | < 0.001 | |
Dyslipidemia | 36 (67.9%) | 155 (93.9%) | 156 (85.7%) | < 0.0001 | < 0.001 | < 0.001 | 0.040 | |
Current cigarette smokers | 22 (41.5%) | 72 (43.6%) | 81 (44.5%) | 0.9272 | - | - | - | |
Obstructive sleep apnea Syndrome | 5 (9.4%) | 55 (33.3%) | 22 (12.2%) | < 0.0001 | < 0.001 | 0.990 | < 0.001 |