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Table 2 Characteristics (categorical parameters) of included subjects. Comparison between OrH, FuH, and EuG men

From: The role of male hypogonadism, aging, and chronic diseases in characterizing adult and elderly men with erectile dysfunction: a cross-sectional study

Parameter

Organic hypogonadism

n = 53

Functional hypogonadism

n = 165

Eugonadism

n = 182

p

(CSQ)

OrH

vs.

FuH

OrH

vs. EuG

FuH

vs. EuG

n (%)

ED (prevalence)

53 (100%)

165 (100%)

168 (92.3%)

0.0002

0.843

0.048

< 0.001

ED (severity)

       

Severe

7 (13.2%)

27 (16.4%)

1 (0.6%)

< 0.0001

0.722

< 0.001

< 0.001

Moderate

19 (35.8%)

64 (38.8%)

15 (8.2%)

Mild-to-moderate

25 (47.2%)

73 (44.2%)

123 (67.6%)

Mild

2 (3.8%)

1 (0.6%)

29 (15.9%)

Normal

0 (0%)

0 (0%)

14 (7.7%)

Age classes, years

       

< 50

36 (67.9%)

19 (11.9%)

32 (17.6%)

< 0.0001

< 0.001

< 0.001

< 0.001

50–59

11 (20.8%)

38 (23%)

49 (26.9%)

60–69

5 (9.4%)

47 (28.5%)

75 (41.2%)

70+

1 (1.9%)

61 (37%)

26 (14.3%)

Comorbidities included in the CCI

       

1 point

Cerebrovascular disease

0 (0%)

18 (10.9%)

11 (6%)

0.0200

-

-

-

Chronic lung disease

3 (5.7%)

43 (26.1%)

37 (20.3%)

0.0061

0.010

0.030

0.347

Congestive heart failure

2 (3.8%)

32 (19.4%)

12 (6.6%)

0.0002

0.010

0.703

< 0.001

Connective tissue disease

1 (1.9%)

8 (4.9%)

11 (6%)

0.4707

-

-

-

Dementia

0 (0%)

5 (3%)

5 (2.8%)

0.6143a

-

-

-

Diabetes without end-organ damage

10 (18.9%)

47 (28.5%)

80 (44%)

0.0004

0.327

< 0.001

< 0.001

Mild liver disease

21 (36.6%)

104 (63%)

72 (39.6%)

< 0.0001

< 0.001

0.990

< 0.001

Myocardial infarction

0 (0%)

38 (23%)

29 (15.9%)

0.0004

< 0.001

< 0.001

0.227

Peripheral vascular disease

0 (0%)

20 (12.1%)

16 (8.8%)

0.0271

0.020

0.040

0.594

Ulcer

0 (0%)

28 (17%)

12 (6.6%)

0.0002

< 0.001

0.139

< 0.001

2 points

Any tumor

3 (5.7%)

21 (12.7%)

27 (14.8%)

0.2116

-

-

-

Diabetes with end-organ damage

1 (1.9%)

91 (55.2%)

52 (28.6%)

< 0.0001

< 0.001

< 0.001

< 0.001

Hemiplegia

0 (0%)

1 (0.6%)

1 (0.6%)

1.0000a

-

-

-

Leukemia

0 (0%)

1 (0.6%)

3 (1.7%)

0.7879a

-

-

-

Lymphoma

0 (0%)

1 (0.6%)

2 (1.1%)

1.0000a

-

-

-

Moderate or severe kidney disease

0 (0%)

46 (27.9%)

20 (11.1%)

< 0.0001

< 0.001

0.010

< 0.001

3 points

Moderate or severe liver disease

2 (3.8%)

5 (3%)

6 (3.3%)

0.9643

-

-

-

6 points

AIDS

0

0

0

-

   

Metastatic solid tumor

1 (1.9%)

2 (1.2%)

5 (2.8%)

0.6200a

-

-

-

Other data

       
 

Arterial hypertension

22 (41.5%)

152 (92.1%)

145 (79.7%)

< 0.0001

< 0.001

< 0.001

< 0.001

 

Dyslipidemia

36 (67.9%)

155 (93.9%)

156 (85.7%)

< 0.0001

< 0.001

< 0.001

0.040

 

Current cigarette smokers

22 (41.5%)

72 (43.6%)

81 (44.5%)

0.9272

-

-

-

 

Obstructive sleep apnea Syndrome

5 (9.4%)

55 (33.3%)

22 (12.2%)

< 0.0001

< 0.001

0.990

< 0.001

  1. Abbreviations: OrH  organic hypogonadism, FuH  functional hypogonadism, EuG  eugonadism, ED  erectile dysfunction, CCI  Charlson Comorbidity Index, AIDS  acquired immunodeficiency syndrome, CSQ  Chi-Square Test,
  2. a = “Fisher Exact Test”