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Table 1 CREB-gene family expression in LIR and HIR boys with cryptorchidism, before and after GnRHa treatment [17, 21, 22]

From: A novel role for CFTR interaction with LH and FGF in azoospermia and epididymal maldevelopment caused by cryptorchidism

Gene

HIR/LIR (RPKM)

log2FC / FDR

−/+ GnRHa treatment (RPKM)

log2FC / FDR

CREB1

13.8/13.0

0.19/0.04

12.58/10.78

−0.68/0.004

ATF2(CREB2)

25.09/23.07

0.21/0.04

22.44/15.42

−0.9/0.0003

CREB3

11.8/13.2

n.s.

12.4/11.6

−0.60/0.008

CREB5

4.50/5.08

n.s.

5.40/5.16

−0.60/0.007

  1. LIR low infertility risk, HIR high infertility risk, FDR false discovery rate, RPKM median expression values expressed in reads per kilobase per million