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Table 1 Epidemiological, biological and histopathological data in Group 1 (idiopathic NOA) and Group 2 (NOA with a history of cryptorchidism) patients

From: Non-obstructive idiopathic azoospermia vs azoospermia with antecedents of cryptorchidism: ways and probabilities of becoming parents

All Patients

(n = 180)

Group 1

Idiopathic NOA

n = 125

Group 2

NOA with History of Cryptorchidism

n = 55

P

Male age (years)

33.3 ± 5.9

33.5 ± 5.3

NS

Female age (years)

29.7 ± 4.1

30.3 ± 3.9

NS

Length of infertility (years)

2.9 ± 1.9

3.4 ± 2.8

NS

TTV (mL)

19.0 ± 7.0

17.8 ± 7.1

NS

FSH (IU/L)

17.0 ± 9.3

17.2 ± 10.0

NS

Inhibin B (pg/mL)

53.3 ± 74.1

57.8 ± 67.6

NS

Testosterone (nmol/L)

13.6 ± 6.2

14.0 ± 5.7

NS

Fresh examination by IVF laboratory

 Positive extraction

34 (27%)

29 (53%)

0.01

 Positive extraction with freezing

32 (26%)

28 (51%)

0.01

Histological examination

 Hypospermatogenesis

49 (39%)

32 (58%)

0.028

 Spermatogenesis with maturation arrest

22 (18%)

1 (2%)

0.007

 Sertoli cell only

54 (43%)

22 (40%)

NS

  1. Data are presented as mean ± SD or as percentages
  2. NOA non-obstructive azoospermia, FSH follicle stimulating hormone, IVF In Vitro Fertilization, NS not-significant, TTV total testicular volume, SD standard deviation