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Table 5 Comparison of allele and genotype frequencies of the tagSNPs between patients with OZ or AZ and controls with NZ

From: Is BRD7 associated with spermatogenesis impairment and male infertility in humans? A case-control study in a Han Chinese population

TagSNPs Allele/Genotype Patients Controls P-values
Total (n = 315) OZ (n = 173) AZ (n = 142) NZ (n = 995) [1] [2] [3]
rs7196135 G 176 (27.9) 98 (28.3) 78 (27.5) 578 (29.0) 0.592 a 0.785 a 0.582 a
A 454 (72.1) 248 (71.7) 206 (72.5) 1412 (71.0)    
GG 28 (8.9) 15 (8.7) 13 (9.2) 79 (8.0) 0.423 a 0.766 a 0.442 a
GA 120 (38.2) 68 (39.3) 52 (36.6) 420 (42.2)    
AA 167 (52.9) 90 (52.0) 77 (54.2) 496 (49.8)    
rs117164075 T 75 (11.9) 40 (11.6) 35 (12.3) 268 (13.5) 0.311 a 0.333 a 0.596 a
C 555 (88.1) 306 (88.4) 249 (87.7) 1722 (86.5)    
TT 5 (1.6) 2 (1.2) 3 (2.1) 15 (1.5) 0.493 b 0.655 b 0.515 b
TC 65 (20.6) 36 (20.8) 29 (20.4) 238 (23.9)    
CC 245 (77.8) 135 (78.0) 110 (77.5) 742 (74.6)    
rs76946718 T 54 (8.6) 32 (9.2) 22 (7.7) 180 (9.0) 0.716 a 0.903 a 0.472 a
C 576 (91.4) 314 (90.8) 262 (92.3) 1810 (91.0)    
TT 1 (0.3) 0 (0.0) 1 (0.7) 7 (0.7) 0.895 b 0.619 b 0.664 b
TC 52 (16.5) 32 (18.5) 20 (14.1) 166 (16.7)    
CC 262 (83.2) 141 (81.5) 121 (85.2) 822 (82.6)    
rs1062348 A 306 (48.6) 172 (49.7) 134 (47.2) 993 (49.9) 0.561 a 0.948 a 0.392 a
G 324 (51.4) 174 (50.3) 150 (52.8) 997 (50.1)    
AA 72 (22.9) 40 (23.1) 32 (22.5) 243 (24.4) 0.832 a 0.862 a 0.646 a
AG 162 (51.4) 92 (53.2) 70 (49.3) 507 (51.0)    
GG 81 (25.7) 41 (23.7) 40 (28.2) 245 (24.6)    
rs79483509 C 134 (21.3) 71 (20.5) 63 (22.2) 446 (22.4) 0.547 a 0.434 a 0.931 a
T 496 (78.7) 275 (79.5) 221 (77.8) 1544 (77.6)    
CC 16 (5.1) 5 (2.9) 11 (7.7) 47 (4.7) 0.619 a 0.547 a 0.136 a
CT 102 (32.4) 61 (35.3) 41 (28.9) 352 (35.4)    
TT 197 (62.5) 107 (61.8) 90 (63.4) 596 (59.9)    
rs62029995 G 130 (20.6) 65 (18.8) 65 (22.9) 383 (19.2) 0.444 a 0.841 a 0.149 a
C 500 (79.4) 281 (81.2) 219 (77.1) 1607 (80.8)    
GG 15 (4.8) 6 (3.5) 9 (6.3) 40 (4.0) 0.742 a 0.942 a 0.316 a
GC 100 (31.7) 53 (30.6) 47 (33.1) 303 (30.5)    
CC 200 (63.5) 114 (65.9) 86 (60.6) 652 (65.5)    
rs11644238 C 140 (22.2) 76 (22.0) 64 (22.5) 424 (21.3) 0.626 a 0.783 a 0.637 a
A 490 (77.8) 270 (78.0) 220 (77.5) 1566 (78.7)    
CC 15 (4.8) 8 (4.6) 7 (4.9) 45 (4.5) 0.879 a 0.995 a 0.892 a
CA 110 (34.9) 60 (34.7) 50 (35.2) 334 (33.6)    
AA 190 (60.3) 105 (60.7) 85 (59.9) 616 (61.9)    
  1. P-values were calculated using Chi-squared testa or Fisher’s exact testb. OZ oligozoospermia, AZ azoospermia, NZ normozoospermia, SNP Single nucleotide polymorphism. Controls vs. [1] Total patients, [2] OZ, [3] AZ