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Table 2 Phenotypic characteristics of men with NOA related to Klinefelter syndrome (n = 19) according to the testicular sperm extraction outcomes

From: Contribution of serum anti-Müllerian hormone in the management of azoospermia and the prediction of testicular sperm retrieval outcomes: a study of 155 adult men

 

Overall

Klinefelter syndrome individuals

n = 19

Positive sperm retrieval

n = 6

Negative sperm retrieval

n = 13

P-value

Age at TESE (years) ¤

[median (IQR)]

30

(28–34)

29.5

(24-34.2)

30

(28–35)

0.63

Mean testicular volume (mL) ¤

[median (IQR)]

2.7

(2-3.5)

3.1

(1.9–4.3)

2.5

(2-3.3)

0.21

FSH (IU /L) ¤

[median (IQR)]

30.5

(18.9–36.7)

29.9

(18.3–34.8)

30.9

(21.8–36.9)

0.61

LH (IU /L) ¤

[median (IQR)]

12.4

(9.8–15.9)

11.7

(9.4–15.2)

12.4

(9.8–17)

0.75

Testosterone (ng/ml) ¤¤

[median (IQR)]

2.6

(1.7–3.6)

3

(2.8–4.5)

1.8

(1.2–3.6)

0.14

AMH (pmol/l) ¤¤

[median (IQR)]

2.3

(1.1-8.6)

8

(3–13)

1.7

(0.8–4.7)

0.01

AMH/Testosterone ¤¤ [median (IQR)]

0.14

(0.1–0.3)

0.3

(0.1–0.4)

0.1

(0.08–0.2)

0.06

Inhibin B (pg/ml) ¤¤

[median (IQR)]

8

(8–10)

8

(8–14)

8

(8–10)

0.60

  1. Statistical analysis was performed by the two-tailed Student’s t (¤) or Mann Whitney U (¤¤) tests
  2. IQR Interquartile range (first and third quartiles), NOA Nonobstructive azoospermia