Fig. 3

Effect of D-chiro-inositol (DCI) treatment on testosterone/estradiol (T/E2) ratio. T/E2 ratio from 10 male volunteers at baseline (t0) and after 30 days of treatment (t1) with 1 g DCI per day are presented as: a median values of T/E2 ratio (box plots) (p = 0.0020; Wilcoxon signed rank sum test). Symbol explanation: see caption of Fig. 1a; b individual T/E2 ratio (before-after treatment). The graph reports the values for each volunteer participating in the study