Fe3+ distribution (%) |
|---|
Group | Control(2 M) | Sham (2 M) | V.I (2 M) | Control (4 M) | Sham (4 M) | V.I-ALA - | V.I-ALA+ |
|---|
Mean ± SEM | 9.72 ± 0.24a | 8.90 ± 0.12b | 37.15 ± 0.57ab | 9.56 ± 0.26c | 9.48 ± 0.28d | 52.65 ± 1.47 cd | 14.96 ± 0.24 cd |
- There is a significant increase in Fe3+ accumulation in the 2 M varicocele group compared to the 2 M control and sham groups. Fe3+ accumulation decreased significantly in the V.I-ALA+ group compared to the V.I-ALA−, 4 M control and sham groups. ALA Alpha lipoic acid, M: month post-surgery or varicocele induction (V.I), V.I-ALA+: varicocele rats treated with ALA+ for 2 to 4 months post induction of varicocele, V.I-ALA−: varicocele rats treated with water as solvent of ALA for 2 to 4 months post induction of varicocele. Statistical analysis (one way ANOVA) for 4 M and for each parameter was carried out between groups and the groups which showed significant different (p-Value < 0.05) were defined by common alphabetic letters
