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Table 2 Comparison of histological parameters and Johnson score between groups

From: Is ferroptosis involved in ROS-induced testicular lesions in a varicocele rat model?

Group

TD

(μm)

MI

(%)

SP

(%)

JS

Control

(2 M)

8.07 ± 0.02a

68.24 ± 0.39d

90.21 ± 0.52 h

9.41 ± 0.57 l

Sham

(2 M)

7.80 ± 0.26

67.52 ± 0.09e

89.21 ± 0.45i

8.16 ± 0.75 m

V.I (2 M)

7.38 ± 0.04a

31.92 ± 0.78de

30.27 ± 0.93hi

6.04 ± 0.45 lm

Control

(4 M)

7.97 ± 0.31b

67.35 ± 0.79f

90.04 ± 1.05j

9.84 ± 1.25n

Sham

(4 M)

7.68 ± 0.17

67.08 ± 0.47 g

88.00 ± 0.57 k

9.00 ± 0.30o

V.I-ALA

7.44 ± 0.16bc

29.88 ± 1.42 fg

32.27 ± 0.74jk

5.43 ± 0.58no

V.I-ALA+

8.10 ± 0.07c

57.92 ± 0.44 fg

67.56 ± 0.97jk

7.53 ± 0.15no

  1. In the 2 M VCL group, measures of MI, SP and JS showed a significant decrease compared to the control and sham groups. While TD showed a significant decrease compared to the control but not sham group. At 4 months, measures of TD, MI, SP and JS were significantly decreased in the V.I-ALA group compared to the control and treated group (V.I-ALA+). ALA Alpha lipoic acid, M Month post-surgery or varicocele induction (V.I), TD Tubular diameter, EH Epithelium height, MI Mitotic index, SP Spermatogenesis percentage and JS Johnson score. Statistical analysis (one way ANOVA) for each time point (2 or 4 M) and for each parameter was carried out between groups and the groups which showed significant different (p-value < 0.05) were defined by common alphabetic letters