Fig. 4
From: Efficacy of relaxin for cisplatin-induced testicular dysfunction and epididymal spermatotoxicity
Effects of RLN on sperm count, quality, motility and MDA levels in CP-treated rats. a Sperm count per mg cauda epididymis. CP treatment significantly reduced sperm concentration, which significantly increased after RLN treatment. b Sperm quality assessed based on morphology. CP treatment reduced the percentage of normal spermatozoa and substantially increased that of dead and abnormal spermatozoa. RLN administration significantly recovered sperm quality to control levels. c Sperm-movement characteristics. RLN administration to CP-treated rats significantly prevented CP-induced side effects in motility characteristics, including percent motile, velocity, ALH, and beat-cross frequency. d Sperm MDA levels. The sperm MDA levels significantly increased following CP treatment and significantly decreased after RLN administration. Values represent the means ± S.E.M.; values with different letters are significantly differences (P < 0.05)