Table 2 Analysis of characteristics of Klinefelter patients with ICPP
Characteristics during precocious puberty | Final puberty-adulthood | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Studies | Karyotype | Age at PP | LH | LH post LHRH | T | TV | Height (cm) | LH | FSH | T | TV |
Leon et al. [9] | Mosaic XY/ XXY/XXXY | 8 | – | – | – | – | 173 | – | – | – | – |
Mühlendahl et al. [10] | 47,XXY | 8.3 | 6.3 | 42 | 3 | 3.4 | 181 | – | – | – | 3 |
Mühlendahl et al. [10] | 47,XXY | 8 | – | – | 1.1 | 5 | 189 | 15 | 39 | 0.1 | 8 |
Bertelloni et al. [11] | 47,XXY | 5 | 4.2 | 37 | 2.8 | 4 | 176 | 16 | 13 | 2.9 | 4 |
Bertelloni et al. [12] | 48,XXYY | 7 | 31 | 130 | 4 | – | 176 | 45 | 130 | 4.2 | – |
Fryns et al. [13] | 47,XXY | – | – | – | – | – | – | – | – | – | – |
Gonzales-Ellis et al. [14] | 47,XXY | 8.5 | 1.9 | – | 0.86 | – | 164 | 3.5 | – | 2.7 | 4 |
Reported case | 47,XXY | 8 | 3.5 | 24 | 4.35 | 6 | 178 | 19 | 22 | 1.16 | 4 |
All (Mean ± SD) | 7.5 ± 1.3 | 9 ± 12 | 58.2 ± 48 | 2.7 ± 1 | 4.6 ± 1 | 177 ± 7 | 20 ± 17 | 51 ± 61 | 2.2 ± 1.4 | 4.6 ± 1.7 | |