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Table 2 Comparison of biomarkers median values of seminal pools used in the EQA program with reference values reported in the literature [12,13,14,15,16]

From: External quality assessment program for biochemical assays of human seminal plasma: a French 6-years experience

  Results from surveys a
Median (Min-Max)
1991 [12]
Mean (Q1-Q3) b
2000 [13]
Median (Q1-Q3)
2002 [14]
Median (Q1-Q3)
2004 [15]
Mean (Q1-Q3)
2010 [16]
Mean (Q1-Q3)
Number of control patients c NA 25 19 230 71 100
Citrate (mmol/L) 27.6 27.8 28.6 NR NR NR
  (24.0–29.1) (18.7–36.9) (18.6–32.9)    
Zinc (mmol/L) 2.11 2.9 NR NR NR NR
  (1.7–2.3) (1.8–4.0)     
Fructose (mmol/L) 16 14.2 12.8 NR 13.9 14.6
  (14.4–17.8) (10.0–18.4) (10.0–18.2)   (9.4–17.6) (11.2–18.0)
Total α-1,4 Glucosidase (UI/L) 19.2 (17.6–21.9) 27.0 (18.2–35.8) NR 23.8 (15.3–32.4) NR NR
Neutral α-1,4 Glucosidase (UI/L) NR 19.5 (12.1–26.9) 24.3 (17.1–31.4) 20.2 (12.3–28.1) NR 14.1 (6.9–21.3)
  1. aExtracted from Table 1
  2. bOriginal data or derived from reported Mean and SD
  3. cFathers or normozoospermic patients
  4. NR Not reported