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Table 4 Association of variables with abnormalities in semen analysis

From: Semen and male genital tract characteristics of patients with Fabry disease: the FERTIFABRY multicentre observational study

Variable n   Univariable analysis Final multivariable model (n = 17)
OR 95% CI p-value OR 95% CI p-value
Age of patient at inclusion 17 For the increase of one year 1.16 1.01–1.33 0.0403 1.19 0.98–1.45 0.0854
Severity of FD 17 1 - Severe vs 0 - Non severe 1.17 0.12–10.99 0.8927    
Kidney failure 17 1 - Yes vs 0 - No 1.33 0.19–9.31 0.7717    
Hypertrophic cardiomyopathy 17 1 - Yes vs 0 - No 0.48 0.07–3.35 0.4592    
Duration of replacement treatment 17 For the increase of 1 year 1.26 0.96–1.65 0.0965 1.28 0.93–1.74 0.1263
Professional or domestic exposure 17 1 - Yes vs 0 - No 0.87 0.05–16.74 0.9292    
Tobacco consumption 17 1 - Yes vs 0 - No 0.48 0.06–3.99 0.4939    
Alcohol consumption 17 1 - Yes vs 0 - No 0.30 0.04–2.2 0.2363    
Duration of FD from first symptoms 16 For the increase of 1 year 1.05 0.96–1.16 0.2866    
Age of patient at the beginning of replacement therapy 17 For the increase of 1 year 1.09 0.98–1.22 0.1222    
Active compound 17 1 - α-galactosidase vs 2 - ß-galactosidase 2.00 0.28–14.2 0.4882 3.77 0.21–66.8 0.3662
  1. Abbreviations: CI = confidence interval; OR = odds ratio; FD = Fabry disease
  2. The references for OR are in bold