Skip to main content

Advertisement

Table 1 Differential expression of Sertoli cell specific genes in Ad- versus Ad+ group (Ad-/Ad+) and in the GnRHa treated versus untreated group (GnRHa)

From: Curative GnRHa treatment has an unexpected repressive effect on Sertoli cell specific genes

Gene ID Name FC Ad-/Ad+ logFC Ad-/Ad+ FDR Ad-/Ad+ FC GnRHa logFC GnRHa FDR GnRHa
AMH Anti-Mullerian Hormone - n.s. n.s. - n.s. n.s.
AR Androgen Receptor - n.s. n.s. 1.5 -0.5821 0.0126
BMP4 Bone Morphogenetic Protein 4 - n.s. n.s. - n.s. n.s.
BMP6 Bone Morphogenetic Protein 6 1.7 -0.7612 0.0030 - n.s. n.s.
CALB2 Calbindin 2 - n.s. n.s. 2.2 -1.1556 0.0034
CDKN1B Cyclin-Dependent Kinase inhibitor 1B (p27, Kip1) - n.s. n.s. 1.7 -0.7845 0.0016
CLDN11 Claudin 11 - n.s. n.s. 1.8 -0.8315 0.0011
CLU Clusterin - n.s. n.s. 1.9 -0.9548 0.0006
CREB1 cAMP Responsive Element Binding protein 1 1.1 0.2000 0.0489 1.6 -0.6888 0.0041
CTSL Cathepsin L - n.s. n.s. 1.7 -0.7492 0.0020
DES Desmin 2.8 -1.4882 0.0014 - n.s. n.s.
DHH Desert Hedgehog - n.s. n.s. - n.s. n.s.
DMRT1 Doublesex and Mab-3 Related Transcription factor 1 - n.s. n.s. 1.7 -0.7838 0.0010
FAS Fas cell surface death receptor - n.s. n.s. - n.s. n.s.
FASLG Fas Ligand (TNF superfamily, member 6) - n.d. n.d. 5.0 2.3154 0.0031
FSHR Follicle stimulating hormone receptor 1.4 0.4915 0.0363 - n.s. n.s.
FGF2 Fibroblast Growth Factor 2 - n.s. n.s. - n.s. n.s.
FGF9 Fibroblast Growth Factor 9 2.1 -1.0605 0.0016 - n.s. n.s.
GATA1 GATA binding protein 1 (globin transcription factor 1) - n.d. n.d. - n.d. n.d.
GATA4 GATA binding protein 4 - n.s. n.s. - n.s. n.s.
GJA1/CX43 Gap Junction protein, Alpha 1/Connexin 43 1.3 0.4018 0.0324 1.9 -0.9516 0.0002
GDNF Glial cell Derived Neurotrophic Factor - n.s. n.s. 2.8 1.4687 0.0036
INHA Inhibin, alpha - n.s. n.s. 1.8 -0.8158 0.0023
INHBA Inhibin, Beta A - n.s. n.s. 1.6 -0.6363 0.0124
INHBB Inhibin, Beta B - n.s. n.s. 1.6 -0.6616 0.0058
KATNAL1 Katanin p60 subunit A-like 1 - n.s. n.s. 1.7 -0.7782 0.0012
KITLG KIT Ligand - n.s. n.s. 2.1 -1.0995 0.0001
KRT18 Keratin 18, type I - n.s. n.s. 1.5 -0.5730 0.0176
NR5A1/SF1 Nuclear Receptor subfamily 5, group A, member 1 - n.s. n.s. - n.s. n.s.
PTGDS Prostaglandin D2 Synthase - n.s. n.s. - n.s. n.s.
SERPINA5 Serpin Family A Member 5 - n.s. n.s. 1.7 -0.7511 0.0076
SOX8 SRY (sex determining region Y)-box 8 2.8 -1.4641 0.0003 - n.s. n.s.
SOX9 SRY (sex determining region Y)-box 9 1.4 0.4983 0.0300 - n.s. n.s.
SRY Sex determining Region Y - n.s. n.s. - n.s. n.s.
TF Transferrin - n.s. n.s. - n.s. n.s.
TJP1/ZO1 Tight Junction Protein 1/Zona Occludens 1 - n.s. n.s. 1.6 -0.6824 0.0102
VIM Vimentin - n.s. n.s. 1.5 -0.5901 0.0352
WT1 Wilms tumor 1 - n.s. n.s. 1.5 -0.5654 0.0180
ZFPM1/FOG1 Zinc Finger Protein, FOG family member 2 - n.s. n.s. - n.s. n.s.
ZFPM2/FOG2 Zinc Finger Protein, FOG family member 2 1.3 0.3695 0.0240 - n.s. n.s.
  1. Absolute fold change (FC), Log 2-fold change (logFC), false discovery rate (FDR), not significant (n.s.), not determined (n.d.)
  2. Absolute fold changes (FC) <2 are highlighted in italic