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Table 1 Levels of hormonal steroids and some of their precursors and metabolites in human seminal plasma and blood serum of fertile men

From: Occurrence and reproductive roles of hormones in seminal plasma

Steroid

Seminal plasma concentration

Plasma/serum concentration

References

Androstanediol (5α-androstane-3α17β-diol)

0.21–1.25

 

[9]

Androstenedione (4-androstene-3,17-dione)

0.30–2.00

3.0–5.0

See Ref. [5]

 

1.20–2.96

 

[9]

 

0.056 (0.035–0.087)

2.036 (1.857–2.228)

[103]

 

3.65 ± 1.63

 

[128]

Cortisol

59–176

140–690

See Ref. [5]

 

13 (10–15)

292 (267–320)

[103]

Cortisone

20.6 (18.8–22.4)

71.6 (68.0–75.5)

[103]

Dehydroepiandrosterone (DHEA)

23.4 ± 10.9

24.3 ± 10.3

[14]

 

4.9 (3.9–6.1)

14.9 (13.2–16.8)

[103]

Dehydroepiandrosterone sulfate (DHEAS)

1400

6850a

See Ref. [35]

Dihydrotestosterone

1.1–1.9

0.87–2.6

See Ref. [5]

 

0.775 (0.634–0.933)

 

[103]

Estrone

0.016 (0.014–0.018)

0.085 (0.070–0.100)

[103]

Estradiol

0.2–0.6

below 0.18

See Ref. [5]

 

0.015–0.066

 

[9]

 

0.256 ± 0.073

 

[40]

 

0.242 ± 0.055

0.086 ± 0.023

[65]

 

0.070 ± 0.009

 

[101]

 

0.014 (0.012–0.017)

0.062 (0.051–0.077)

[103]

 

0.596 ± 0.193

0.095 ± 0.04

[116]

Estriol

0.149 (0.114–0.191)

0.031 (0.021–0.049)

[103]

7α-Hydroxy-DHEA

1.67 ± 0.66

1.41 ± 0.77

[14]

 

0.903 (0.782–1.045)

0.913 (0.801–1.041)

[103]

7β-Hydroxy-DHEA

1.45 ± 0.67

1.23 ± 0.60

[14]

 

0.210 (0.174–0.246)

0.489 (0.437–0.545)

[103]

16α-Hydroxy-DHEA

1.06 ± 0.15

0–1.86

[15]

17-Hydroxy pregnenolone

0.358 (0.271–0.463)

4.933 (4.241–5.715)

[103]

17α-Hydroxyprogesterone

1.62 ± 1.26

1.30–5.40b

[128]

7-oxo-DHEA

0.116 (0.089–0.145)

0.129 (0.106–0.159)

[103]

Pregnenolone

0.626 (0.537–0.730)

1.138 (0.916–1.390)

[103]

Progesterone

1.43 ± 0.56

0–3.20b

[128]

Testosterone

0.3–4.6

10–35

See Ref. [5]

 

1.18–8.32

10.0–32.2

[9]

 

0.07 (0.04–0.11)

11.5 (10.6–12.4)

[103]

  1. The concentration ranges or means ± S.D. or means with 95.0% confidence intervals in parenthesis in nmol/L are shown
  2. aStrongly dependent on age, bData from author’s laboratory