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Table 3 Effects of paternal age on IVF

From: Sperm quality and paternal age: effect on blastocyst formation and pregnancy rates

Paternal age (years) 20 < Age < 29 30 < Age < 39 40 < Age < 50 Age > 51 P value
Mean maternal age (years ± SD) 29.39 ± 5.11 34.22 ± 4.18 37.08 ± 3.43 37.00 ± 5.77 <0.0001
Number of IVF 114 524 211 10  
Mean number of inseminated oocytes ± SD 10.11 ± 5.72 9.99 ± 5.44 9.31 ± 5.26 7.30 ± 6.17 0.1024
Fertilization rate (%) 64.01 67.66 65.99 42.46 <0.0001
Mean number of embryos at day 2 ± SD 6.76 ± 4.29 7.01 ± 4.58 6.38 ± 4.12 3.40 ± 4.67 0.0104
Mean number of embryos at day 3 ± SD 6.13 ± 3.88 6.31 ± 4.17 5.72 ± 4.02 2.90 ± 4.15 0.0048
Mean number of embryos in prolonged culture ± SD 3.51 ± 3.68 4.09 ± 4.16 3.60 ± 3.86 1.60 ± 3.53 0.0408
Mean number of obtained blastocysts ± SD 1.74 ± 2.35 2.25 ± 2.73 1.78 ± 2.30 0.90 ± 2.02 0.0319
Rate of blastocyst formation (%) 49.50 54.97 49.41 56.25 0.0255
Mean number of transferred blastocysts ± SD 0.053 ± 0.224 0.113 ± 0.322 0.118 ± 0.324 0.000 ± 0.000 0,6987
Mean number of frozen blastocysts ± SD 0.667 ± 1.420 1.040 ± 1.830 1.070 ± 1.780 0.700 ± 1.640 0.3081
Rate of useful blastocysts (%) 41.41 51.10 66.93 77.78 <0.0001
Rate of clinical pregnancies (%) 28.60 38.90 39.70 14.30 0.1151
Rate of miscarriages (%) 17.90 18.60 34.40 NR 0.3504
  1. SD standard deviation, NR not reported (missing data)