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Table 2 Semen characteristics in the various pathological groups of men studied and comparisons with the two groups of healthy fertile men

From: Semen quality of 4480 young cancer and systemic disease patients: baseline data and clinical considerations

  CSD PPW TGCT HD NHL L S BT Behcet MS F p-value
n 1448 208 2315 1175 439 360 208 40 68 73 - -
Seminal volume (ml) 3.8 ± 1.8a 4.2 ± 2.0 3.7 ± 2.0 *** 3.2 ± 1.9**,**** 3.1 ± 1.8**,**** 2.9 ± 1.7**,**** 3.2 ± 1.8**,**** 3.5 ± 1.8 3.2 ± 1.9 **** 3.2 ± 1.9*,**** 19 <0.0001
3.5 (2.5–4.8)b 3.9 (2.7–5.2) 3.4 (2.3–4.8) 2.9 (1.9–4.1) 2.9 (1.9–4.1) 2.6 (1.7–3.9) 2.9 (2.0–4.3) 3.1 (2.1–4.4) 2.8 (1.5–4.6) 2.9 (1.7–4.5)
Sperm concentration (×106/ml) 99.1 ± 73.8 94.2 ± 71.8 36.1 ± 48.5**,**** 79.4 ± 103.1** 81.2 ± 91.7** 63.0 ± 96.3**,**** 72.8 ± 83.2** 86.7 ± 118.4 116.6 ± 125.8 98.3 ± 87.4 118 <0.0001
82.4 (48.4–133.0) 74.0 (40.6–125.0) 19.6 (5.4–48.8) 52.0 (18.1–104.0) 55.6 (18.0–115.2) 25.6 (1.6–88.0) 44.7 (15.9–96.5) 56.8 (9.8–94.6) 83.2 (27.6–167.7) 74.6 (30.6–131.7)
Total sperm count (×106) 362 ± 328 383 ± 350 127 ± 174**,**** 250 ± 388**,**** 245 ± 289**,**** 179 ± 293**,**** 233 ± 307**,**** 287 ± 394 357 ± 428 312 ± 439 89 <0.0001
281 (152–486) 291 (153–488) 64 (16–178) 147 (45–323) 160 (38–324) 71 (4–209) 124 (39–316) 140 (34–331) 221 (63–419) 159 (105–357)
Progressively motile sperm (%) 65 ± 12**** 50 ± 13** 43 ± 19**,**** 47 ± 20** 43 ± 21**,**** 33 ± 21**,**** 41 ± 19**,**** 27 ± 17**,**** 47 ± 18** 43 ± 19**,*** 300 <0.0001
65 (60–75) 48 (42–58) 45 (30–56) 50 (35–60) 45 (30–60) 35 (15–50) 40 (30–55) 30 (10–40) 50 (35–60) 45 (30–60)
Morphologically normal sperm (%) 61 ± 13 **** 49 ± 15** 34 ± 19**,**** 41 ± 21**,**** 37 ± 20**,**** 29 ± 18**,**** 31 ± 20**,**** 20 ± 15**,**** 36 ± 22**,**** 41 ± 16**,**** 313 <0.0001
62 (53–70) 52 (39–61) 33 (19–48) 42 (25–58) 37 (21–52) 29 (15–41) 28 (14–46) 17 (7–32) 33 (16–59) 40 (30–54)
  1. For all pathological conditions, differences between groups of men were investigated by one-way analysis of variance. For pair-wise comparisons, post hoc Tukey tests were carried out, with: * p < 0.05 and ** p < 0.01 in comparison to CSD and ***p < 0.05 and ****p <0.01 in comparison to PPW
  2. aMean ± SD; bMedian (IQ range)