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Table 2 Semen characteristics in the various pathological groups of men studied and comparisons with the two groups of healthy fertile men

From: Semen quality of 4480 young cancer and systemic disease patients: baseline data and clinical considerations

 

CSD

PPW

TGCT

HD

NHL

L

S

BT

Behcet

MS

F

p-value

n

1448

208

2315

1175

439

360

208

40

68

73

-

-

Seminal volume (ml)

3.8 ± 1.8a

4.2 ± 2.0

3.7 ± 2.0 ***

3.2 ± 1.9**,****

3.1 ± 1.8**,****

2.9 ± 1.7**,****

3.2 ± 1.8**,****

3.5 ± 1.8

3.2 ± 1.9 ****

3.2 ± 1.9*,****

19

<0.0001

3.5 (2.5–4.8)b

3.9 (2.7–5.2)

3.4 (2.3–4.8)

2.9 (1.9–4.1)

2.9 (1.9–4.1)

2.6 (1.7–3.9)

2.9 (2.0–4.3)

3.1 (2.1–4.4)

2.8 (1.5–4.6)

2.9 (1.7–4.5)

Sperm concentration (×106/ml)

99.1 ± 73.8

94.2 ± 71.8

36.1 ± 48.5**,****

79.4 ± 103.1**

81.2 ± 91.7**

63.0 ± 96.3**,****

72.8 ± 83.2**

86.7 ± 118.4

116.6 ± 125.8

98.3 ± 87.4

118

<0.0001

82.4 (48.4–133.0)

74.0 (40.6–125.0)

19.6 (5.4–48.8)

52.0 (18.1–104.0)

55.6 (18.0–115.2)

25.6 (1.6–88.0)

44.7 (15.9–96.5)

56.8 (9.8–94.6)

83.2 (27.6–167.7)

74.6 (30.6–131.7)

Total sperm count (×106)

362 ± 328

383 ± 350

127 ± 174**,****

250 ± 388**,****

245 ± 289**,****

179 ± 293**,****

233 ± 307**,****

287 ± 394

357 ± 428

312 ± 439

89

<0.0001

281 (152–486)

291 (153–488)

64 (16–178)

147 (45–323)

160 (38–324)

71 (4–209)

124 (39–316)

140 (34–331)

221 (63–419)

159 (105–357)

Progressively motile sperm (%)

65 ± 12****

50 ± 13**

43 ± 19**,****

47 ± 20**

43 ± 21**,****

33 ± 21**,****

41 ± 19**,****

27 ± 17**,****

47 ± 18**

43 ± 19**,***

300

<0.0001

65 (60–75)

48 (42–58)

45 (30–56)

50 (35–60)

45 (30–60)

35 (15–50)

40 (30–55)

30 (10–40)

50 (35–60)

45 (30–60)

Morphologically normal sperm (%)

61 ± 13 ****

49 ± 15**

34 ± 19**,****

41 ± 21**,****

37 ± 20**,****

29 ± 18**,****

31 ± 20**,****

20 ± 15**,****

36 ± 22**,****

41 ± 16**,****

313

<0.0001

62 (53–70)

52 (39–61)

33 (19–48)

42 (25–58)

37 (21–52)

29 (15–41)

28 (14–46)

17 (7–32)

33 (16–59)

40 (30–54)

  1. For all pathological conditions, differences between groups of men were investigated by one-way analysis of variance. For pair-wise comparisons, post hoc Tukey tests were carried out, with: * p < 0.05 and ** p < 0.01 in comparison to CSD and ***p < 0.05 and ****p <0.01 in comparison to PPW
  2. aMean ± SD; bMedian (IQ range)