From: Testosterone and gonadotropins but not SHBG vary with CKD stages in young and middle aged men
CKD 1 | CKD 2 | CKD 3 | CKD 4 | CKD 5 | p | |
---|---|---|---|---|---|---|
N = 101 | 23 | 20 | 27 | 13 | 18 | |
S- Testosterone (nmol/L) | 14.89 ± 3.91 | 14.10 ± 4.15 | 13.22 ± 3.81 | 10.81 ± 4.53 | 8.82 ± 3.81 | <0.01 |
S-SHBG (nmol/L) | 29.56 ± 12.73 | 35.50 ± 13.03 | 34.55 ± 13.51 | 33.07 ± 12.9 | 28.55 ± 13.47 | ns |
Free testosterone nmol/L | 0.33 ± 0.10 | 0.28 ± 0.06 | 0.25 ± 0.05 | 0.19 ± 0.07 | 0.19 ± 0.08 | <0.01 |
S-LH (U/L) | 4.16 ± 2.07 | 3.33 ± 1.40 | 6.77 ± 4.22 | 6.50 ± 2.71 | 9.43 ± 7.60 | <0.01 |
S-FSH (U/L) | 3.67 ± 2.65 | 3.67 ± 2.06 | 6.85 ± 4.04 | 5.21 ± 4.82 | 13.51 ± 6.98 | ns |
S-Prolactin (μg/L) | 7.76 ± 2.04 | 8.54 ± 3.36 | 9.24 ± 2.47 | 16.50 ± 12.54 | 17.41 ± 2.13 | <0.01 |
S-Cholesterol (mmol/L) | 5.04 ± 1.14 | 5.03 ± 1.65 | 4.85 ± 1.06 | 4.72 ± 0.72 | 5.20 ± 1.30 | n.s. |
S-HDL (mmol/L) | 1.20 ± 0.31 | 1.25 ± 0.24 | 1.2 ± 0.29 | 1.09 ± 0.24 | 1.24 ± 0.48 | n.s. |
S-LDL (mmol/L) | 2.98 ± 0.99 | 3.34 ± 1.08 | 3.02 ± 0.97 | 2.70 ± 0.71 | 3.03 ± 1.21 | n.s. |
S-Tg (mmol/L) | 1.65 ± 1.12 | 1.17 ± 0.66 | 1.33 ± 0.68 | 2.17 ± 1.43 | 2.61 ± 1.52 | <0.01 |
S-glucose (mmol/L) | 5.13 ± 0.59 | 5.07 ± 0.45 | 5.18 ± 0.67 | 4.80 ± 0.67 | 5.18 ± 0.62 | n.s. |