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Table 4 Multivariate analysis for predicting testosterone surge (LC-MS/MS)

From: Clinical endocrinological evaluation of the gonadal axis (testosterone, LH and FSH) in prostate cancer patients switched from a GnRH antagonist to a LHRH agonist

 

Univariate analysis

Multivariate analysis (linear analysis)

Variables

P value

Partial regression coefficient

95% CI lower

95% CI upper

P value

Age

0.140

    

Period of degarelix administration

0.004

−0.091

−0.150

−0.032

0.004

GS

0.354

    

Stage

0.241

    

D’Amico classification

0.149

    

Serum T (before ADT)

0.688

    

Serum T (after switching therapy)

0.948

    

Serum LH (before ADT)

0.820

    

Serum LH (after switching therapy)

<0.001

0.445

0.339

0.551

<0.001

Serum FSH (before therapy)

0.747

    

Serum FSH (after switching therapy)

0.406

    
  1. GS Gleason score; ADT androgen deprivation therapy; T testosterone; LH luteinizing hormone; FSH follicle-stimulating hormone; CI confidence interval
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Basic and Clinical Andrology

ISSN: 2051-4190