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Table 4 Multivariate analysis for predicting testosterone surge (LC-MS/MS)

From: Clinical endocrinological evaluation of the gonadal axis (testosterone, LH and FSH) in prostate cancer patients switched from a GnRH antagonist to a LHRH agonist

  Univariate analysis Multivariate analysis (linear analysis)
Variables P value Partial regression coefficient 95% CI lower 95% CI upper P value
Age 0.140     
Period of degarelix administration 0.004 −0.091 −0.150 −0.032 0.004
GS 0.354     
Stage 0.241     
D’Amico classification 0.149     
Serum T (before ADT) 0.688     
Serum T (after switching therapy) 0.948     
Serum LH (before ADT) 0.820     
Serum LH (after switching therapy) <0.001 0.445 0.339 0.551 <0.001
Serum FSH (before therapy) 0.747     
Serum FSH (after switching therapy) 0.406     
  1. GS Gleason score; ADT androgen deprivation therapy; T testosterone; LH luteinizing hormone; FSH follicle-stimulating hormone; CI confidence interval