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  1. Sperm cryopreservation is an effective method of fertility preservation for disease-related and social sperm freezing. In total, 662 subjects (range: 15–65 years-of-age; mean: 33.49 ± 8.79 years-of-age) were i...

    Authors: Wenhao Tang, Chenyao Deng, Jiangman Gao, Senlin Tian, Nan Wei, Bin Li, Jianfei Song, Liang Zhang, Han Wu and Hui Jiang
    Citation: Basic and Clinical Andrology 2022 32:18
  2. Vasitis is a rare condition that may be challenging for the clinical practitioner. Sometimes it is misdiagnosed as incarcerated inguinal hernia; thus, patients end up receiving unnecessary surgery. Compared wi...

    Authors: Yi Hong Li, Zhon min Huang, Ji kuen Yu, Yi Sheng Lin, Chao Yu Hsu and Min Che Tung
    Citation: Basic and Clinical Andrology 2022 32:19
  3. At present, L-carnitine (LC) and coenzyme Q10 (CoQ10), as used clinically to treat male infertility caused by asthenozoospermia (ASZ) is still mainly administered orally, but some patients with ASZ still show ...

    Authors: Chengren Gou, Zidong Zhou, Zongping Chen, Kun Wang, Congcong Chen, Bo Chen, Ningrui Pan and Xu He
    Citation: Basic and Clinical Andrology 2022 32:17
  4. The seminal virome and its implications for fertility remain poorly understood. To date, there are no defined panels for the detection of viruses of clinical interest in seminal samples.

    Authors: Beatriz Helena Dantas Rodrigues de Albuquerque, Maryana Thalyta Ferreira Camara de Oliveira, Janaína Ferreira Aderaldo, Mychelle de Medeiros Garcia Torres and Daniel Carlos Ferreira Lanza
    Citation: Basic and Clinical Andrology 2022 32:16
  5. Previous studies have reported that some patients with headless spermatozoa have poor semen quality, but there has been no published systematic analysis of semen quality in patients with different proportions ...

    Authors: Li-juan Ying, Lin Yu, Tingting Yang, Ying-bi Wu, Jin-yan Xu, Ye-lin Jia, Yan Zheng and Fuping Li
    Citation: Basic and Clinical Andrology 2022 32:20
  6. To evaluate the stiffness of the tunica albuginea (TA), we used a new noninvasive diagnostic technique called shear wave elastography (SWE). We determined whether SWE values are correlated with the degree of p...

    Authors: Francesco Trama, Ester Illiano, Fabrizio Iacono, Antonio Ruffo, Giovanni di Lauro, Achille Aveta, Felice Crocetto, Celeste Manfredi and Elisabetta Costantini
    Citation: Basic and Clinical Andrology 2022 32:15
  7. The possible effects of COVID-19 vaccines on reproductive health and male fertility in particular have been discussed intensely by the scientific community and the public since their introduction during the pa...

    Authors: Ziad H. Abd, Samir A. Muter, Ruya Abdulhadi M. Saeed and Omar Ammar
    Citation: Basic and Clinical Andrology 2022 32:13
  8. Fournier’s gangrene (FG) is a necrotizing fasciitis caused by aerobic and anaerobic bacterial infection that involves genitalia and perineum. Males, in their 60 s, are more affected with 1.6 new cases/100.000/...

    Authors: Alessio Paladini, Giovanni Cochetti, Angelica Tancredi, Matteo Mearini, Andrea Vitale, Francesca Pastore, Paolo Mangione and Ettore Mearini
    Citation: Basic and Clinical Andrology 2022 32:12
  9. Exposure of men and women to environmental reprotoxic agents is associated with impaired fertility and pregnancy rates after assisted reproductive treatment (ART). Nevertheless, such exposures are generally no...

    Authors: Nadia Nouiakh, Claire Sunyach, Sarah-Lyne Jos, Irène Sari-Minodier, Catherine Metzler-Guillemain, Blandine Courbiere, Florence Bretelle and Jeanne Perrin
    Citation: Basic and Clinical Andrology 2022 32:11
  10. Cryptorchidism occurs frequently in children with cystic fibrosis. Among boys with cryptorchidism and abrogated mini-puberty, the development of the epididymis and the vas deferens is frequently impaired. This...

    Authors: Faruk Hadziselimovic, Gilvydas Verkauskas and Michael Stadler
    Citation: Basic and Clinical Andrology 2022 32:10
  11. Excess weight and metabolic disorders have a negative impact on male reproductive functions. The mechanisms involved are numerous and complex and epigenetic mechanisms may also be involved, notably through the...

    Authors: Sarah Saget, Laurent Kappeler, Valérie Grandjean, Patricia Leneuve, Isabelle Berthaut, Céline Faure, Sébastien Czernichow, Chrystèle Racine, Rachel Lévy and Charlotte Dupont
    Citation: Basic and Clinical Andrology 2022 32:9
  12. Infertility related to varicocele, infections, metabolic dysfunctions, oxidative stress and environmental toxicants is also associated with inflammatory processes that ultimately lead to the activation of the ...

    Authors: Marziyeh Tavalaee, Mohsen Rahmani, Joël R. Drevet and Mohammad Hossein Nasr-Esfahani
    Citation: Basic and Clinical Andrology 2022 32:8
  13. Sarcoidosis is a multi-system disease characterized by the formation of non-caseating granulomas in various organs. The lungs remain the most frequently affected organ, whereas lesions in the genitourinary sys...

    Authors: Magdalena Ostrowska, Piotr Świniarski, Adam Ostrowski, Filip Ryszard Kowalski, Jan Adamowicz, Dariusz Grzanka, Tomasz Adam Drewa and Kajetan Juszczak
    Citation: Basic and Clinical Andrology 2022 32:7
  14. Severe or complete asthenozoospermia is a rare entity that can lead to male infertility. In this study, we explored whether different extents of severe or complete asthenozoospermia could affect intracytoplasm...

    Authors: Tong Chen, Demin Fan, Xianlong Wang, Changlin Mao, Yaru Chu, Haobo Zhang, Wen Liu, Sentai Ding, Qingyong Liu, Mingzhen Yuan and Jiaju Lu
    Citation: Basic and Clinical Andrology 2022 32:6
  15. Erectile dysfunction (ED) often occurs due to cavernous nerve injury (CNI) after colorectal surgery. Cell-based therapies have great potential for the treatment of CNI-related ED; however, it needs to be optim...

    Authors: Zhenbin Zhang, Pan Nie, Wende Yang, Xiaolei Ma, Zehong Chen and Hongbo Wei
    Citation: Basic and Clinical Andrology 2022 32:5
  16. Penile schwannoma is a rare tumor. They commonly present as an asymptomatic, painless and slow growing mass. Other presentations include sexual dysfunction, most commonly dyspareunia, followed by erectile dysf...

    Authors: Chan Ming Tow, Jonathan Tang, Chan Ming Chun and Joe Lee King Chien
    Citation: Basic and Clinical Andrology 2022 32:4
  17. A very small number of studies have indicated that azoospermia or negative testicular sperm extraction (TESE) outcomes are linked to depression or erectile dysfunction. However, the data are often weak, confli...

    Authors: Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN and Florence BOITRELLE
    Citation: Basic and Clinical Andrology 2022 32:3
  18. Spermatogenesis in mammals is a heat-sensitive developmental pathway incompatible with the typical mammalian body temperature of 37 °C. It is thought that this is the reason why the testicles of most mammalian...

    Authors: Faruk Hadziselimovic
    Citation: Basic and Clinical Andrology 2022 32:2
  19. The ischiocavernosus muscle (ICM) encompasses a pair of short pinnate muscles attached to the pelvic ring. The ICM begins at the ischial tuberosity and ends at the crus of the penis while covering the surface ...

    Authors: Chengren Gou, Tong Liu, Zongping Chen, Zidong Zhou, Tao Song, Kaiyi Mao, Congcong Chen and Bo Chen
    Citation: Basic and Clinical Andrology 2022 32:1
  20. Hormones like testosterone play a crucial role in performance enhancement and muscle growth. Therefore, various attempts to increase testosterone release and testosterone concentration have been made, especial...

    Authors: Eduard Isenmann, Moritz Schumann, Hannah L. Notbohm, Ulrich Flenker and Philipp Zimmer
    Citation: Basic and Clinical Andrology 2021 31:32
  21. Non-obstructive azoospermia (NOA) with history of cryptorchidism and idiopathic NOA are the most common forms of NOA without genetic aetiology. Of all patients with one of these two types of NOA, only a few wi...

    Authors: Jacques Singh Sangwan, Claire Petit, Romane Sainte Rose, Cynthia Frapsauce, Laura Dijols, Jean Marc Rigot and Fabrice Guérif
    Citation: Basic and Clinical Andrology 2021 31:30
  22. Recent studies suggest that serum vitamin D may be associated with semen parameters. In the present cross-sectional study, we attempted to investigate the association between serum vitamin D levels and semen p...

    Authors: Hossein Hajianfar, Elham Karimi, Negar Mollaghasemi, Sheyda Rezaei and Arman Arab
    Citation: Basic and Clinical Andrology 2021 31:29
  23. Several recent journal articles report that d-chiro-inositol (DCI), primarily known as insulin second messenger, influences steroidogenesis. In particular, new evidence is arising on DCI ability to regulate aroma...

    Authors: Maurizio Nordio, Philip Kumanov, Alfonsina Chiefari and Giulia Puliani
    Citation: Basic and Clinical Andrology 2021 31:28
  24. Although chromosome rearrangements are responsible for spermatogenesis failure, their impact depends greatly on the chromosomes involved. At present, karyotyping and Y chromosome microdeletion screening are th...

    Authors: Farah Ghieh, Anne-Laure Barbotin, Julie Prasivoravong, Sophie Ferlicot, Béatrice Mandon-Pepin, Joanne Fortemps, Henri-Jean Garchon, Valérie Serazin, Clara Leroy, François Marcelli and François Vialard
    Citation: Basic and Clinical Andrology 2021 31:27
  25. Although widely used, slow freezing considerably modifies the functions of human spermatozoa. Cryopreservation induces nuclear sperm alterations and cryo-capacitation, reducing the chances of pregnancy. Hypota...

    Authors: Hanae Pons-Rejraji, Solène Vorilhon, Asmaa Difrane, Sandra Dollet, Céline Bourgne, Marc Berger, Laure Chaput, Bruno Pereira, Cyril Bouche, Joël R. Drevet and Florence Brugnon
    Citation: Basic and Clinical Andrology 2021 31:26
  26. The use of flow cytometry (FC) to evaluate sperm DNA fragmentation via deoxynucleotidyl transferase terminal fluorescein dUTP nick-end labeling (TUNEL) has shown inconsistencies compared with conventional fluo...

    Authors: Niloofar Sadeghi, Marziyeh Tavalaee, Abbas Kiani-Esfahani, Aron Moazamian, Parviz Gharagozloo, Robert J. Aitken, Joël R. Drevet and Mohammad Hossein Nasr-Esfahani
    Citation: Basic and Clinical Andrology 2021 31:23
  27. Extracellular Vesicles (EVs) are membrane-limited particles containing proteins, lipids, metabolites and nucleic acids that are secreted by healthy and cancerous cells. These vesicles are very heterogeneous in...

    Authors: Anne-Sophie Neyroud, Régina Chiechio, Marina Yefimova, Maria Josè Lo Faro, Nathalie Dejucq-Rainsford, Sylvie Jaillard, Pascale Even-Hernandez, Valérie Marchi and Célia Ravel
    Citation: Basic and Clinical Andrology 2021 31:25
  28. A direct association between metabolic syndrome (MetS) and sperm production/function has been proposed. In this cross-sectional study, we aimed to determine the impact of MetS on sperm survival. Men from infer...

    Authors: Minh Tam Le, Hiep Tuyet Thi Nguyen, Hong Nhan Thi Dang, Thai Thanh Thi Nguyen, Trung Van Nguyen and Quoc Huy Vu Nguyen
    Citation: Basic and Clinical Andrology 2021 31:22
  29. Sperm cryopreservation, an effective method for preserving male fertility, is very advantageous for men suffering from cancer. Unfortunately, as both physicians and cancer patients are unaware of the possibili...

    Authors: Xiao Liu, Bo Liu, Shasha Liu, Yang Xian, Wenrui Zhao, Bin Zhou, Xiao Xiao, Li Wang, Xiaofang Zhu, Bizhen Shu, Min Jiang and Fuping Li
    Citation: Basic and Clinical Andrology 2021 31:24
  30. Bromodomain-containing protein 7 (BRD7), a member of the bromodomain-containing protein family, plays important roles in chromatin modification and transcriptional regulation. A recent model of Brd7-knockout mice...

    Authors: Tianrong He, Mohan Liu, Dachang Tao, Xiangyou Leng, Zhaokun Wang, Shengyu Xie, Yangwei Zhang, Xinyue Zhang, Xiaolan Tan, Yunqiang Liu and Yuan Yang
    Citation: Basic and Clinical Andrology 2021 31:19
  31. Whereas the initially strategy for the genetic analysis of male infertility was based on a candidate gene approach, the development of next-generation sequencing technologies (such as whole-exome sequencing (W...

    Authors: Farah Ghieh, Anne-Laure Barbotin, Clara Leroy, François Marcelli, Nelly Swierkowsky-Blanchard, Valérie Serazin, Béatrice Mandon-Pepin and François Vialard
    Citation: Basic and Clinical Andrology 2021 31:21
  32. Asthenozoospermia is a usual male infertility factor, characterized by decreased semen quality. It has been revealed that antioxidants improve sperm function, enhance endogenous antioxidant activities, and pro...

    Authors: Reza Asadpour, Morteza Taravat, Maryam Rahbar, Mohammadrasoul Khoshniyat and Gholamreza Hamidian
    Citation: Basic and Clinical Andrology 2021 31:20
  33. During the last decades, the abuse of anabolic androgenic steroids (AASs) has become popular among professional and recreational athletes. The abuse of AASs leads to decreased levels of sex hormones, but the a...

    Authors: Jasmina Sretenovic, Jovana Joksimovic Jovic, Ivan Srejovic, Vladimir Zivkovic, Katarina Mihajlovic, Milica Labudovic-Borovic, Svetlana Trifunovic, Verica Milosevic, Dejan Lazic, Sergey Bolevich, Vladimir Jakovljevic and Zoran Milosavljevic
    Citation: Basic and Clinical Andrology 2021 31:17
  34. Testicular sperm extraction (TESE) is the method of choice for recovering spermatozoa in patients with azoospermia. However, the lack of reliable biomarkers makes it impossible to predict sperm retrieval outco...

    Authors: Hamza Benderradji, Julie Prasivoravong, François Marcelli, Anne-Laure Barbotin, Sophie Catteau-Jonard, Carole Marchetti, Catherine Guittard, Philippe Puech, Valérie Mitchell, Jean-Marc Rigot, Arnauld Villers, Pascal Pigny and Clara Leroy
    Citation: Basic and Clinical Andrology 2021 31:15
  35. The testis represents one place where the progenitor of vitamin D is converted into its active form. Loss of one testis was suggested to result in reduced vitamin D serum levels. Vitamin D deficiency would rep...

    Authors: Klaus-Peter Dieckmann, Osama Andura, Uwe Pichlmeier, Klaus Martin Otte, Hendrik Isbarn and Christian Wülfing
    Citation: Basic and Clinical Andrology 2021 31:14

    The Correction to this article has been published in Basic and Clinical Andrology 2021 31:18

  36. Androgen deficiency affects men in the adulthood, causing several harmful effects at the reproductive and behavioural levels. Since aromatase is an enzyme that catalyses the conversion of androgens to estrogen...

    Authors: Giovanni Monastra, Mónica Vazquez-Levin, Maria Salome Bezerra Espinola, Gabriele Bilotta, Antonio Simone Laganà and Vittorio Unfer
    Citation: Basic and Clinical Andrology 2021 31:13
  37. Sperm growth and maturation are correlated with the expression levels of Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1), a widely expressed protein in the human testicles. The decrease in LRWD1...

    Authors: Jui-Hsiang Hung, Han-Yi Cheng, Yung-Chieh Tsai, Hsien-An Pan, Hany A. Omar, Chien-Chih Chiu, Yin-Mei Su, Yung-Ming Lin and Yen-Ni Teng
    Citation: Basic and Clinical Andrology 2021 31:12
  38. Diet, one of the components of lifestyle, has been believed to have associations with erectile dysfunction (ED). However, whether there is an association between plant-based diet and ED is remains to be explor...

    Authors: Yi Lu, Jiaqi Kang, Zhongjia Li, Xiao Wang, Kang Liu, Kechong Zhou, Wei Wang and Chen Shen
    Citation: Basic and Clinical Andrology 2021 31:11
  39. Over the last years, there has been an increasing concern about a global decline in men’s fertility. Specifically, some evidence indicates that sperm quality has decreased over the last years. However, reports...

    Authors: Lucía Rosa-Villagrán, Natalibeth Barrera, José Montes, Carlos Riso and Rossana Sapiro
    Citation: Basic and Clinical Andrology 2021 31:8
  40. Spermatogenesis is a complex process regulated by a multitude of genes. The identification and characterization of male-germ-cell-specific genes is crucial to understanding the mechanisms through which the cel...

    Authors: Hela Bellil, Farah Ghieh, Emeline Hermel, Béatrice Mandon-Pepin and François Vialard
    Citation: Basic and Clinical Andrology 2021 31:9
  41. Occludin protein is the primary assembling protein of TJs and the structural basis for tight junction formation between Sertoli cells in the spermatogenic epithelium. The expression of miR-122-5p and occludin ...

    Authors: Limin Liu, Maoying Zhu, Xiaoli Liu, Lumin Fei, Jianyun Shen and Deyu Chen
    Citation: Basic and Clinical Andrology 2021 31:7
  42. Ferroptosis is an iron-dependent cell death that is distinct from apoptosis. Based on excessive amounts of iron and reactive oxygen species in varicocele (VCL) rats, we hypothesize that ferroptosis might be in...

    Authors: Erfaneh Shaygannia, Mohammad H. Nasr-Esfahani, Fattah Sotoodehnejadnematalahi and Kazem Parivar
    Citation: Basic and Clinical Andrology 2021 31:10
  43. Gonadotropin releasing hormone agonist (GnRHa) treatment following surgery to correct cryptorchidism restores mini-puberty via endocrinological and transcriptional effects and prevents adult infertility in mos...

    Authors: Faruk Hadziselimovic, Gilvydas Verkauskas and Michael B. Stadler
    Citation: Basic and Clinical Andrology 2021 31:6
  44. Penile prothesis (PP) is the gold-standard treatment of drug-refractory erectile dysfunction (ED). While postoperative outcomes have been widely described in the literature, there are few data about patient sa...

    Authors: Valentine Frydman, Ugo Pinar, Maher Abdessater, William Akakpo, Pietro Grande, Marie Audouin, Pierre Mozer, Emmanuel Chartier-Kastler, Thomas Seisen and Morgan Roupret
    Citation: Basic and Clinical Andrology 2021 31:4
  45. Premature ejaculation (PE) is a multifactorial problem with a complicated aetiology that has detrimental effects on female partners’ sexual function. However, there is a lack of studies on the relationship bet...

    Authors: Hu Li, Pan Gao, Jingjing Gao, Xu Wu, Guodong Liu, Yutian Dai, Hui Jiang and Xiansheng Zhang
    Citation: Basic and Clinical Andrology 2021 31:5
  46. In a previous report, we investigated whether the size of male genitalia similarly exposed to serum testosterone during aging could change with age and found that penile length almost stopped increasing during...

    Authors: Hiroshi Ikegaya, Motofumi Suzuki, Hiroki Kondou, Taketo Kawai, Yusuke Sato, Tadaichi Kitamura and Haruki Kume
    Citation: Basic and Clinical Andrology 2021 31:3

Basic and Clinical Andrology is the official journal of the French Society of Andrology (SALF).

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