Table 2 Gene expression profiles in testicular cells before and after GnRHa treatment

Class 1

 KDM6A

19.9/11.3

-0.81/0.0009

Histone demethylase

Lc/Sc

 TET1

11.9/7.1

-0.73/0.002

Functional demethylation

Lc

Class 2

 ARID4A

12.5/9

-0.48/0.03

HDAC bridging molecule

Lc/Sc/Sptg/Sptc

 ARID5B

21.6/15.3

-0.49/0.03

Histone demethylase

Lc/Sc/Sptg

 ATRX

33.7/19.3

-0.79/0.002

Methyltransferase

Lc/Sc/Sptg

 DNMT3A

24.6/19.86

n.s

Methyltransferase

LC/Sc/Sptg

 EPC1

23.0/14.1

-0.7/0.002

Histone acetyltransferase

Lc/Sptg

 HDAC1

22.2/12.7

-0.80/0.0008

Deacetylase

Lc/Sc/Sptg/Sptc

 HDAC2

15.5/9.7

-0.67/0.004

Deacetylase

Lc/Sc/Sptg/Sptcs

 HDAC3

22.2/16.2

-0.45/0.045

Deacetylase

Lc/Sc/Sptg

 HDAC8

7.7/5.7

-0.48/0.052

Histone decrotonylase

Lc/Sc/Sptg

 INO80D

12.1/7.9

-0.60/0.01

Chromatin remodeling

Lc/Sc/Sptg

 KDM4A

27.6/20.3

-0.44/0.052

Histone demethylase

Lc/Sc/Sptg

 KMT2E

35.8/24.2

-0.56/0.02

Methyltransferase

Lc/Sc/Sptg

 PBRM1

27.2/16.6

-0.7/0.004

Chromatin remodeling

Lc/Sc/Sptg/Sptc

 PRMT2

27.5/16.9

-0.69/0.004

Arginine methyltransferase

Lc/Sc/Sptg

 SETD7

22.3/12.3

-0.85/0.0006

Methyl transferase

Lc/Sc/Sptg

 SMARCA1

96.2/52.6

-0.87/0.0004

Chromatin regulator

Lc/Sc/Sptg

 SMARCA2

37.3/24.0

-0.87/0.0009

Chromatin regulator

Lc/Sc/Sptg

 TSPYL4

12.4/9.2

-0.43/0.054

Chromatin and histone binding

Lc/Sc/Sptg/Sptc

Class 3

 ARID2

19.3/11.6

-0.72/0.003

Chromatin remodeling

Sptd/Sptc

 ASH1L

43.3/36.8

-0.62/0.01

Methyltransferase

Sptg/Sptc

 BAZ2B

47.0/27.6

-0.76/0.003

Chromatin remodeling

Sptc/Sptd

 SCML2

26.3/14.5

-0.85/0.0005

Histone transcriptional repressor

Sptg/Sptc

 SETD2

40.0/24.5

-0.7/0.005

Methyltransferase

Sptg/Sptc

 TRDMT1

4.89/3.5

-0.45/0.048

Methyltransferase

Sptc