Fig. 1
From: Cooperative cell–cell actin network remodeling to perform Gap junction endocytosis
Gap junctions examined in cultured Cx43-GFP transfected Sertoli cells by electron microscopy. A This electron micrograph shows the junction between two cells, separated by an electron dense line corresponding to a GJP (large open arrow). The Donor cell contains large mitochondria (M) and part of the nucleus (N) is visible. A large AGJ is present in the cytoplasm of the Acceptor cell. The curved GJP originating from the Donor cell, is indicated by an arrow. The inset (Bar 50 nm) shows the area outlined by the white rectangle at higher magnification, showing a small endocytic vesicle (white arrow). B A curved C-shaped plaque (open arrow) separates the two adjacent Donor and Acceptor cells. C A U-shaped plaque (open arrow) defines the Donor (D) and the Acceptor (A) cells. D An Instability-shaped plaque (open arrow) precedes the future AGJ (Donor cell: D; Acceptor cell: A)