Table 4 DFI Results of Infertility Cohort. Shows the DNA Fragmentation Index (DFI) results of cohort of 209 human male infertility subjects as compared to multiple different lifestyle variables. Logistics regression models were used to test the relationship between categorical variables and DFI, and linear regression models were used to find the relationship between continuous variables and DFI
From: Effects of alcohol use on sperm chromatin structure, a retrospective analysis
Outcome: DFI High | |||||
Variable | Value | Estimate | Standard error | t-value | p-value |
Age | age in years | 0.19 | 0.06 | 2.94 | *0.0037 |
Exposure to heat (yes/no) | yes | 0.42 | 0.91 | 0.46 | 0.6493 |
Outside/inside job | inside | 2.70 | 3.55 | 0.76 | 0.4482 |
Outside/inside job | outside | 1.18 | 3.62 | 0.33 | 0.7442 |
Exposure to radiation/chemicals (yes/no) | yes | 0.02 | 0.94 | 0.02 | 0.9868 |
Tobacco use (yes/no) | yes | 0.64 | 0.86 | 0.75 | 0.4559 |
Level of alcohol use | heavy | -0.26 | 1.22 | -0.21 | 0.8308 |
Level of alcohol use | moderate | 1.09 | 0.93 | 1.17 | 0.2428 |
Level of alcohol use | rare | -0.29 | 0.91 | -0.32 | 0.7510 |
Outcome: DFI Moderate | |||||
Variable | Value | Estimate | Standard error | t-value | p-value |
Age | age in years | 0.15 | 0.07 | 2.17 | *0.0309 |
Exposure to heat (yes/no) | yes | -0.09 | 0.98 | -0.09 | 0.9252 |
Outside/inside job | inside | 1.68 | 3.79 | 0.44 | 0.6577 |
Outside/inside job | outside | 0.09 | 3.86 | 0.02 | 0.9823 |
Exposure to radiation/chemical (yes/no) | yes | 0.16 | 1.01 | 0.16 | 0.8702 |
Tobacco use (yes/no) | yes | 0.54 | 0.92 | 0.59 | 0.5577 |
Level of alcohol use | heavy | -1.22 | 2.65 | -0.46 | 0.6460 |
Level of alcohol use | moderate | -1.31 | 1.25 | -1.05 | 0.2962 |
Level of alcohol use | rare | -1.49 | 0.98 | -1.51 | 0.1321 |
Outcome: Total DFI | |||||
Variable | Value | Estimate | Standard error | t-value | p-value |
Age | age in years | 0.34 | 0.12 | 2.80 | *0.0056 |
Exposure to heat (yes/no) | yes | 0.35 | 1.72 | 0.20 | 0.8394 |
Outside/inside job | inside | 4.37 | 6.67 | 0.66 | 0.5130 |
Outside/inside job | outside | 1.25 | 6.81 | 0.18 | 0.8544 |
Exposure to radiation/chemicals (yes/no) | yes | 0.19 | 1.77 | 0.11 | 0.9139 |
Tobacco use (yes/no) | yes | 1.19 | 1.61 | 0.74 | 0.4613 |
Level of alcohol use | heavy | -0.77 | 2.28 | -0.34 | 0.7370 |
Level of alcohol use | moderate | 0.02 | 1.75 | 0.01 | 0.9896 |