Table 5 Comparison of allele and genotype frequencies of the tagSNPs between patients with OZ or AZ and controls with NZ
TagSNPs | Allele/Genotype | Patients | Controls | P-values | ||||
|---|---|---|---|---|---|---|---|---|
Total (n = 315) | OZ (n = 173) | AZ (n = 142) | NZ (n = 995) | [1] | [2] | [3] | ||
rs7196135 | G | 176 (27.9) | 98 (28.3) | 78 (27.5) | 578 (29.0) | 0.592 a | 0.785 a | 0.582 a |
A | 454 (72.1) | 248 (71.7) | 206 (72.5) | 1412 (71.0) | ||||
GG | 28 (8.9) | 15 (8.7) | 13 (9.2) | 79 (8.0) | 0.423 a | 0.766 a | 0.442 a | |
GA | 120 (38.2) | 68 (39.3) | 52 (36.6) | 420 (42.2) | ||||
AA | 167 (52.9) | 90 (52.0) | 77 (54.2) | 496 (49.8) | ||||
rs117164075 | T | 75 (11.9) | 40 (11.6) | 35 (12.3) | 268 (13.5) | 0.311 a | 0.333 a | 0.596 a |
C | 555 (88.1) | 306 (88.4) | 249 (87.7) | 1722 (86.5) | ||||
TT | 5 (1.6) | 2 (1.2) | 3 (2.1) | 15 (1.5) | 0.493 b | 0.655 b | 0.515 b | |
TC | 65 (20.6) | 36 (20.8) | 29 (20.4) | 238 (23.9) | ||||
CC | 245 (77.8) | 135 (78.0) | 110 (77.5) | 742 (74.6) | ||||
rs76946718 | T | 54 (8.6) | 32 (9.2) | 22 (7.7) | 180 (9.0) | 0.716 a | 0.903 a | 0.472 a |
C | 576 (91.4) | 314 (90.8) | 262 (92.3) | 1810 (91.0) | ||||
TT | 1 (0.3) | 0 (0.0) | 1 (0.7) | 7 (0.7) | 0.895 b | 0.619 b | 0.664 b | |
TC | 52 (16.5) | 32 (18.5) | 20 (14.1) | 166 (16.7) | ||||
CC | 262 (83.2) | 141 (81.5) | 121 (85.2) | 822 (82.6) | ||||
rs1062348 | A | 306 (48.6) | 172 (49.7) | 134 (47.2) | 993 (49.9) | 0.561 a | 0.948 a | 0.392 a |
G | 324 (51.4) | 174 (50.3) | 150 (52.8) | 997 (50.1) | ||||
AA | 72 (22.9) | 40 (23.1) | 32 (22.5) | 243 (24.4) | 0.832 a | 0.862 a | 0.646 a | |
AG | 162 (51.4) | 92 (53.2) | 70 (49.3) | 507 (51.0) | ||||
GG | 81 (25.7) | 41 (23.7) | 40 (28.2) | 245 (24.6) | ||||
rs79483509 | C | 134 (21.3) | 71 (20.5) | 63 (22.2) | 446 (22.4) | 0.547 a | 0.434 a | 0.931 a |
T | 496 (78.7) | 275 (79.5) | 221 (77.8) | 1544 (77.6) | ||||
CC | 16 (5.1) | 5 (2.9) | 11 (7.7) | 47 (4.7) | 0.619 a | 0.547 a | 0.136 a | |
CT | 102 (32.4) | 61 (35.3) | 41 (28.9) | 352 (35.4) | ||||
TT | 197 (62.5) | 107 (61.8) | 90 (63.4) | 596 (59.9) | ||||
rs62029995 | G | 130 (20.6) | 65 (18.8) | 65 (22.9) | 383 (19.2) | 0.444 a | 0.841 a | 0.149 a |
C | 500 (79.4) | 281 (81.2) | 219 (77.1) | 1607 (80.8) | ||||
GG | 15 (4.8) | 6 (3.5) | 9 (6.3) | 40 (4.0) | 0.742 a | 0.942 a | 0.316 a | |
GC | 100 (31.7) | 53 (30.6) | 47 (33.1) | 303 (30.5) | ||||
CC | 200 (63.5) | 114 (65.9) | 86 (60.6) | 652 (65.5) | ||||
rs11644238 | C | 140 (22.2) | 76 (22.0) | 64 (22.5) | 424 (21.3) | 0.626 a | 0.783 a | 0.637 a |
A | 490 (77.8) | 270 (78.0) | 220 (77.5) | 1566 (78.7) | ||||
CC | 15 (4.8) | 8 (4.6) | 7 (4.9) | 45 (4.5) | 0.879 a | 0.995 a | 0.892 a | |
CA | 110 (34.9) | 60 (34.7) | 50 (35.2) | 334 (33.6) | ||||
AA | 190 (60.3) | 105 (60.7) | 85 (59.9) | 616 (61.9) | ||||